L(+)-Gulonic acid gamma-lactone
- Product Name
- L(+)-Gulonic acid gamma-lactone
- CAS No.
- 1128-23-0
- Chemical Name
- L(+)-Gulonic acid gamma-lactone
- Synonyms
- L-GULONOLACTONE;L-GULONO-1,4-LACTONE;L-GULONIC GAMMA-LACTONE;Reduced ascorbate;L-GULONIC-G-LACTONE;GULONOLACTONE(RG) 1g;Reduced Ascorbic Acid;L-GULONO-GAMMA-LACTONE;L(+)-GULONO-1,4-LACTONE;L-GulonicAcid-y-Lactone
- CBNumber
- CB2341914
- Molecular Formula
- C6H10O6
- Formula Weight
- 178.14
- MOL File
- 1128-23-0.mol
L(+)-Gulonic acid gamma-lactone Property
- Melting point:
- 187-190 °C(lit.)
- alpha
- 54.5 º (c=2, water 57.5 ºC)
- Boiling point:
- 230.35°C (rough estimate)
- Density
- 1.3253 (rough estimate)
- refractive index
- 56 ° (C=2, H2O)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
- pka
- 12.06±0.60(Predicted)
- form
- Viscous Solution
- color
- White to Off-white
- optical activity
- [α]19/D +55°, c = 4 in H2O
- Water Solubility
- Soluble in water
- BRN
- 83002
- InChI
- InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3+,4-,5+/s3
- InChIKey
- SXZYCXMUPBBULW-QICJDPMJNA-N
- SMILES
- [C@H]1([C@@H](O)CO)OC(=O)[C@@H](O)[C@H]1O |&1:0,1,8,10,r|
- CAS DataBase Reference
- 1128-23-0(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29400090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 310301
- Product name
- L-Gulonic acid γ-lactone
- Purity
- 95%
- Packaging
- 5g
- Price
- $82.6
- Updated
- 2025/07/31
- Product number
- 310301
- Product name
- L-Gulonic acid γ-lactone
- Purity
- 95%
- Packaging
- 25g
- Price
- $254
- Updated
- 2025/07/31
- Product number
- G0235
- Product name
- L-(+)-Gulonic Acid gamma-Lactone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $77
- Updated
- 2025/07/31
- Product number
- G0235
- Product name
- L-(+)-Gulonic Acid gamma-Lactone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $235
- Updated
- 2025/07/31
- Product number
- G9845-01
- Product name
- L-Gulono-1,4-lactone
- Packaging
- 10g
- Price
- $355
- Updated
- 2021/12/16
L(+)-Gulonic acid gamma-lactone Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
L-Gulono-1,4-lactone is a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C.
Definition
ChEBI: L-gulono-1,4-lactone is the furanose form of gulonolactone having L-configuration. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a L-gulonic acid.
Synthesis
50-81-7
1128-23-0
The general procedure for the synthesis of L-gulosonic acid-γ-lactone from L-ascorbic acid was as follows: 10% Pd/C catalyst (8.3 g) was added to a solution of L-ascorbic acid (83.9 g, 0.477 mol) in water (600 mL). The reaction mixture was placed in a Parr hydrogenator and hydrogenated for 62 hours at 48 psi hydrogen pressure and 18°C. Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was concentrated under vacuum to afford L-gulosonic acid-γ-lactone (81.0 g, 96% yield) as an off-white solid. The resulting solid was dried in a vacuum oven at 50 °C for 18 h. The melting point was measured to be 182-184 °C.
References
[1] Journal of Organic Chemistry, 1981, vol. 46, # 14, p. 2976 - 2977
[2] Patent: US2004/54172, 2004, A1
[3] Patent: US2003/232889, 2003, A1. Location in patent: Page/Page column 12
[4] Synlett, 2017, vol. 28, # 8, p. 970 - 972
[5] Tetrahedron Asymmetry, 1996, vol. 7, # 9, p. 2711 - 2720
L(+)-Gulonic acid gamma-lactone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L(+)-Gulonic acid gamma-lactone manufacturers
- Product
- L(+)-Gulonic acid gamma-lactone 1128-23-0
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-13
- Product
- L-Gulono-1,4-lactone 1128-23-0
- Price
- US $1290.00/Kg
- Min. Order
- 0.100Kg
- Purity
- 99 %
- Supply Ability
- 5000 Kg
- Release date
- 2025-06-01
- Product
- L(+)-Gulonic acid gamma-lactone 1128-23-0
- Price
- US $0.00/G
- Min. Order
- 10G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-14