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L(+)-Gulonic acid gamma-lactone

Product Name
L(+)-Gulonic acid gamma-lactone
CAS No.
1128-23-0
Chemical Name
L(+)-Gulonic acid gamma-lactone
Synonyms
L-GULONOLACTONE;L-GULONO-1,4-LACTONE;L-GULONIC GAMMA-LACTONE;Reduced ascorbate;L-GULONIC-G-LACTONE;GULONOLACTONE(RG) 1g;Reduced Ascorbic Acid;L-GULONO-GAMMA-LACTONE;L(+)-GULONO-1,4-LACTONE;L-GulonicAcid-y-Lactone
CBNumber
CB2341914
Molecular Formula
C6H10O6
Formula Weight
178.14
MOL File
1128-23-0.mol
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L(+)-Gulonic acid gamma-lactone Property

Melting point:
187-190 °C(lit.)
alpha 
54.5 º (c=2, water 57.5 ºC)
Boiling point:
230.35°C (rough estimate)
Density 
1.3253 (rough estimate)
refractive index 
56 ° (C=2, H2O)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pka
12.06±0.60(Predicted)
form 
Viscous Solution
color 
White to Off-white
optical activity
[α]19/D +55°, c = 4 in H2O
Water Solubility 
Soluble in water
BRN 
83002
InChI
InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3+,4-,5+/s3
InChIKey
SXZYCXMUPBBULW-QICJDPMJNA-N
SMILES
[C@H]1([C@@H](O)CO)OC(=O)[C@@H](O)[C@H]1O |&1:0,1,8,10,r|
CAS DataBase Reference
1128-23-0(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29400090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
310301
Product name
L-Gulonic acid γ-lactone
Purity
95%
Packaging
5g
Price
$82.6
Updated
2025/07/31
Sigma-Aldrich
Product number
310301
Product name
L-Gulonic acid γ-lactone
Purity
95%
Packaging
25g
Price
$254
Updated
2025/07/31
TCI Chemical
Product number
G0235
Product name
L-(+)-Gulonic Acid gamma-Lactone
Purity
>98.0%(GC)
Packaging
5g
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
G0235
Product name
L-(+)-Gulonic Acid gamma-Lactone
Purity
>98.0%(GC)
Packaging
25g
Price
$235
Updated
2025/07/31
Usbiological
Product number
G9845-01
Product name
L-Gulono-1,4-lactone
Packaging
10g
Price
$355
Updated
2021/12/16
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L(+)-Gulonic acid gamma-lactone Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

L-Gulono-1,4-lactone is a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C.

Definition

ChEBI: L-gulono-1,4-lactone is the furanose form of gulonolactone having L-configuration. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a L-gulonic acid.

Synthesis

50-81-7

1128-23-0

The general procedure for the synthesis of L-gulosonic acid-γ-lactone from L-ascorbic acid was as follows: 10% Pd/C catalyst (8.3 g) was added to a solution of L-ascorbic acid (83.9 g, 0.477 mol) in water (600 mL). The reaction mixture was placed in a Parr hydrogenator and hydrogenated for 62 hours at 48 psi hydrogen pressure and 18°C. Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was concentrated under vacuum to afford L-gulosonic acid-γ-lactone (81.0 g, 96% yield) as an off-white solid. The resulting solid was dried in a vacuum oven at 50 °C for 18 h. The melting point was measured to be 182-184 °C.

References

[1] Journal of Organic Chemistry, 1981, vol. 46, # 14, p. 2976 - 2977
[2] Patent: US2004/54172, 2004, A1
[3] Patent: US2003/232889, 2003, A1. Location in patent: Page/Page column 12
[4] Synlett, 2017, vol. 28, # 8, p. 970 - 972
[5] Tetrahedron Asymmetry, 1996, vol. 7, # 9, p. 2711 - 2720

L(+)-Gulonic acid gamma-lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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L(+)-Gulonic acid gamma-lactone Suppliers

Americas 1 Belgium 1 Canada 2 China 175 Europe 2 France 1 Germany 3 India 7 Ireland 1 Japan 4 Switzerland 4 United Kingdom 6 United States 28 Global 235
PARAGOS
Tel
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Email
info@paragos.com
Country
Germany
ProdList
6371
Advantage
39
Service Chemical Inc.
Tel
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Fax
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Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
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Fax
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Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from L(+)-Gulonic acid gamma-lactone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
L(+)-Gulonic acid gamma-lactone 1128-23-0
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-13
R&D Scientific Inc.
Product
L-Gulono-1,4-lactone 1128-23-0
Price
US $1290.00/Kg
Min. Order
0.100Kg
Purity
99 %
Supply Ability
5000 Kg
Release date
2025-06-01
WUHAN FORTUNA CHEMICAL CO., LTD
Product
L(+)-Gulonic acid gamma-lactone 1128-23-0
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-14

1128-23-0, L(+)-Gulonic acid gamma-lactoneRelated Search:

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