ChemicalBook > CAS DataBase List > 2-Chloro-N,N-dimethylacetamide

2-Chloro-N,N-dimethylacetamide

Product Name
2-Chloro-N,N-dimethylacetamide
CAS No.
2675-89-0
Chemical Name
2-Chloro-N,N-dimethylacetamide
Synonyms
EOS-61825;AKOS BBS-00000943;2-Chloro-N,N-dimethy;CHLOROACETYLDIMETHYLAMINE;N,N-DIMETHYLCHOROACETAMIDE;N,N-DIMETHYLCHLOROACETAMIDE;N-DiMethyl-2-chloroacetaMide;N,N-DIMETHYL-2-CHLOROACETAMIDE;2-CHLORO-N,N-DIMETHYLACETAMIDE;2-CHLORO-N,N-DIMETHYL ACETAMINE
CBNumber
CB2343589
Molecular Formula
C4H8ClNO
Formula Weight
121.57
MOL File
2675-89-0.mol
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2-Chloro-N,N-dimethylacetamide Property

Melting point:
15-16 °C
Boiling point:
98-100°C/11mm
Density 
1.182 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.479
Flash point:
98-100°C/11mm
storage temp. 
Store below +30°C.
solubility 
Chloroform (Slightly), Hexane (Slightly), Methanol (Slightly)
pka
-0.95±0.70(Predicted)
form 
Liquid
color 
Clear colorless to pale yellow
BRN 
969568
InChIKey
XBPPLECAZBTMMK-UHFFFAOYSA-N
CAS DataBase Reference
2675-89-0(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 3
WGK Germany 
3
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
24350
Product name
2-Chloro-N,N-dimethylacetamide
Purity
≥97.0% (GC)
Packaging
25mL
Price
$138
Updated
2024/03/01
TCI Chemical
Product number
C3011
Product name
2-Chloro-N,N-dimethylacetamide
Packaging
5G
Price
$44
Updated
2024/03/01
TCI Chemical
Product number
C3011
Product name
2-Chloro-N,N-dimethylacetamide
Packaging
25G
Price
$150
Updated
2024/03/01
Alfa Aesar
Product number
H50229
Product name
2-Chloro-N,N-dimethylacetamide, 97%
Packaging
250mg
Price
$69.65
Updated
2024/03/01
Alfa Aesar
Product number
H50229
Product name
2-Chloro-N,N-dimethylacetamide, 97%
Packaging
1g
Price
$226.65
Updated
2024/03/01
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2-Chloro-N,N-dimethylacetamide Chemical Properties,Usage,Production

Uses

2-Chloro-N,N-dimethylacetamide is N,M-dialkyl amide used as an organic catalyst in the preparation of phosphorylated thiosemicarbazide.

Uses

2-Chloro-N,N-dimethylacetamide (N,N-dimethylchloroacetamide) was used in the synthesis of (S)-carbinoxamine.

Synthesis

In a 500 mL four-necked flask, sodium hydrogen carbonate 126.0 g (1.50 mol) and 146.8 g of toluene were added, and the mixture was stirred while cooling. The internal temperature was maintained below 5 ° C, 112.9 g (1.00 mol) of chloroacetyl chloride was added dropwise over 4 hours, and 49.6 g (1.10 mol) of dimethylamine gas was blown over 4 hours. After stirring at -2 to 1 ° C. for 1 hour, the reaction solution was filtrated under reduced pressure to remove inorganic salt crystals by filtration. The crystals were washed with 100 g of toluene, and the filtrate and washings were combined. After separating and removing the aqueous layer in the filtrate washings, the toluene layer was concentrated under reduced pressure to obtain 113.2 g (0.93 mol) of oily 2-chloro-N, N-dimethylacetamide. The yield was 93.1%.

2-Chloro-N,N-dimethylacetamide Preparation Products And Raw materials

Raw materials

Dimethylamine hydrochloride Chloroacetyl chloride Sodium bicarbonate Dichloromethane Sodium hydroxide Dimethylamine

Preparation Products

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2-Chloro-N,N-dimethylacetamide Suppliers

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View Lastest Price from 2-Chloro-N,N-dimethylacetamide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-Chloro-N,N-dimethylacetamide 2675-89-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-26
Henan Aochuang Chemical Co.,Ltd.
Product
2-Chloro-N,N-dimethylacetamide 2675-89-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
N,N-Dimethyl-2-chloroacetamide 2675-89-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

2675-89-0, 2-Chloro-N,N-dimethylacetamideRelated Search:

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  • 2-Chloro-N,N-dimethylacetamide, 97%,
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