RESCINNAMINE
- Product Name
- RESCINNAMINE
- CAS No.
- 24815-24-5
- Chemical Name
- RESCINNAMINE
- Synonyms
- Rozex;Apolon;Rescin;Tuareg;ANAPREL;Anapral;Cartric;Moderil;Resipal;Apoterin
- CBNumber
- CB2344278
- Molecular Formula
- C35H42N2O9
- Formula Weight
- 634.73
- MOL File
- 24815-24-5.mol
RESCINNAMINE Property
- Melting point:
- 238-239°C
- alpha
- D24 -97° (c = 1 in chloroform)
- Boiling point:
- 669.26°C (rough estimate)
- Density
- 1.2161 (rough estimate)
- refractive index
- 1.5300 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- pKa 6.4 (Uncertain)
- color
- Pale Beige to Pale Brown
- Stability:
- Stable, but darkens slowly in light. Incompatible with strong oxidizing agents.
- EPA Substance Registry System
- Rescinnamine (24815-24-5)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 25-20/21/22
- Safety Statements
- 22-45-36
- RIDADR
- 1544
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Hazardous Substances Data
- 24815-24-5(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- R144720
- Product name
- Rescinnamine
- Packaging
- 10mg
- Price
- $765
- Updated
- 2021/12/16
- Product number
- API0004052
- Product name
- RESCINNAMINE
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $3614
- Updated
- 2021/12/16
- Product number
- FC61500
- Product name
- Cartric
- Packaging
- 10mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FC61500
- Product name
- Cartric
- Packaging
- 25mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FC61500
- Product name
- Cartric
- Packaging
- 50mg
- Price
- $150
- Updated
- 2021/12/16
RESCINNAMINE Chemical Properties,Usage,Production
Description
This Rauwolfia alkaloid is found in the barks of R. serpentina and R. vomitora and was originally given the name Reserpinine, this being altered to avoid confusion with another alkaloid of the same name (q.v.). The base has [α]17D - 99.2° (c 1.3, CHCI3). From chemical degradation and spectroscopic analysis, the structure has been established as the 3:4: 5-trimethoxycinnamoyl ester of reserpic acid.
Chemical Properties
white to cream powder
Uses
Rescinnamine occurs in the roots of a num ber of Rauwolfia species. Therapeutically, itis used as an antihypertensive agent.
Uses
Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.
Definition
ChEBI: Rescinnamine is a methyl ester, an organic heteropentacyclic compound and an indole alkaloid. It has a role as an antihypertensive agent. It derives from a hydride of a yohimban.
brand name
Moderil (Pfizer).
General Description
Odorless white to cream colored crystalline powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
The neat material darkens slowly on exposure to light. In solution this occurs more rapidly. .
Health Hazard
The pharmacological properties of rescinnamine are similar to those of reserpine, butthe side effects are low. It acts as a sedativeand hypotensive. A dose of 0.25 mg/day mayproduce the effect of sleepiness in humans.Excessive doses may produce depression,nightmare, nausea, diarrhea, and hypotension.
LD50 value, oral (rats): 1000 mg/kg
The carcinogenicity of rescinnamine inanimals or humans is unknown.
Fire Hazard
Flash point data for RESCINNAMINE are not available. RESCINNAMINE is probably combustible.
Purification Methods
Crystallise it from *benzene, MeOH or aqueous Me2CO. The hydrochloride has m 232o(dec) (from MeOH) and [] D -74o (MeOH). It is an antihypertensive. [Klohs et al. J Am Chem Soc 77 2241 1955, Beilstein 25 III/IV 1323.]
References
Haack e tal., Naturwiss., 41, 214 (1954)
Klohs, Draper, Keller.,J. Amer. Chem. Soc., 77,2241 (1955)
Kidd., Chem. & Ind., 1481 (1955)
Popelak, Lettenbauer., Arch. Pharm., 296,261 (1963)
RESCINNAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from RESCINNAMINE manufacturers
- Product
- RESCINNAMINE 24815-24-5
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 20 tons
- Release date
- 2023-03-23