ChemicalBook > CAS DataBase List > 1,8-Naphthyridine

1,8-Naphthyridine

Product Name
1,8-Naphthyridine
CAS No.
254-60-4
Chemical Name
1,8-Naphthyridine
Synonyms
1, 8 - nalidixic;1,8-NAPHTHYRIDINE;1,8-Pyridopyridine;1,8-Diazanapthalene;1,8-Naphthyridine>1,8-DIAZANAPHTHALENE;PYRIDO[2,3-B]PYRIDINE;1,8-NAPHTHYRIDINE 98+%;1,8-Diazanaphthalene 98%;1,8-Naphthyridine(6CI,7CI,8CI,9CI)
CBNumber
CB2352000
Molecular Formula
C8H6N2
Formula Weight
130.15
MOL File
254-60-4.mol
More
Less

1,8-Naphthyridine Property

Melting point:
99.8-99.9°C
Boiling point:
248.9±13.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.39
form 
powder to crystal
pka
3.55±0.10(Predicted)
color 
White to Light yellow to Light orange
InChIKey
FLBAYUMRQUHISI-UHFFFAOYSA-N
CAS DataBase Reference
254-60-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2902900000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
N0464
Product name
1,8-Naphthyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$146
Updated
2024/03/01
TCI Chemical
Product number
N0464
Product name
1,8-Naphthyridine
Purity
>98.0%(GC)
Packaging
100mg
Price
$25
Updated
2024/03/01
TRC
Product number
B504303
Product name
1,8-Naphthyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
018153
Product name
[1,8]Naphthyridine
Packaging
500mg
Price
$52
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-DP
Product name
1,8-Diazanaphthalene
Packaging
1g
Price
$150
Updated
2021/12/16
More
Less

1,8-Naphthyridine Chemical Properties,Usage,Production

Description

1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.

Uses

1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands.

Definition

ChEBI: 1,8-naphthyridine is a naphthyridine in which the nitrogens are situated at positions 1 and 8.

Purification Methods

Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.]

1,8-Naphthyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,8-Naphthyridine Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
More
Less

View Lastest Price from 1,8-Naphthyridine manufacturers

Dideu Industries Group Limited
Product
1,8-NAPHTHYRIDINE 254-60-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-26
Career Henan Chemical Co
Product
1,8-NAPHTHYRIDINE 254-60-4
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2020-01-14