ChemicalBook > CAS DataBase List > 1,8-Naphthyridine

1,8-Naphthyridine

Product Name
1,8-Naphthyridine
CAS No.
254-60-4
Chemical Name
1,8-Naphthyridine
Synonyms
1, 8 - nalidixic;1,8-NAPHTHYRIDINE;1,8-Pyridopyridine;1,8-Diazanapthalene;1,8-Naphthyridine>1,8-DIAZANAPHTHALENE;PYRIDO[2,3-B]PYRIDINE;1,8-NAPHTHYRIDINE 98+%;1,8-Diazanaphthalene 98%;1,8-Naphthyridine(6CI,7CI,8CI,9CI)
CBNumber
CB2352000
Molecular Formula
C8H6N2
Formula Weight
130.15
MOL File
254-60-4.mol
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1,8-Naphthyridine Property

Melting point:
99.8-99.9°C
Boiling point:
248.9±13.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.39
form 
powder to crystal
pka
3.55±0.10(Predicted)
color 
White to Light yellow to Light orange
InChIKey
FLBAYUMRQUHISI-UHFFFAOYSA-N
CAS DataBase Reference
254-60-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2902900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
N0464
Product name
1,8-Naphthyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$146
Updated
2024/03/01
TCI Chemical
Product number
N0464
Product name
1,8-Naphthyridine
Purity
>98.0%(GC)
Packaging
100mg
Price
$25
Updated
2024/03/01
TRC
Product number
B504303
Product name
1,8-Naphthyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
018153
Product name
[1,8]Naphthyridine
Packaging
500mg
Price
$52
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-DP
Product name
1,8-Diazanaphthalene
Packaging
1g
Price
$150
Updated
2021/12/16
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1,8-Naphthyridine Chemical Properties,Usage,Production

Description

1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.

Uses

1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands.

Definition

ChEBI: 1,8-naphthyridine is a naphthyridine in which the nitrogens are situated at positions 1 and 8.

Purification Methods

Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.]

1,8-Naphthyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Nalidixic acid
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1,8-Naphthyridine Suppliers

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View Lastest Price from 1,8-Naphthyridine manufacturers

Dideu Industries Group Limited
Product
1,8-NAPHTHYRIDINE 254-60-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-26
Career Henan Chemical Co
Product
1,8-NAPHTHYRIDINE 254-60-4
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2020-01-14

254-60-4, 1,8-NaphthyridineRelated Search:

1,8-Naphthyridine 7,10-dichloro-2-methoxybenzo[b]-1,5-naphthyridine 5,6,7,8-TETRAHYDRO-6-(PHEHYLMETHYL)-1,6-NAPHTHYRIDIN-3-AMINE 3-(CHLOROMETHYL)-6-(TRIFLUOROMETHYL)PYRIDINE 3-ACETYL-2-METHYL-1,6-NAPHTHYRIDINE 3-BROMO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE 2-CHLORO-1,8-NAPHTHYRIDINE 5-Bromo-1,2,3,4-tetrahydro-[1,7]naphthyridine 5-CHLORO-1,6-NAPHTHYRIDINE 5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine 5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDIN-3-OL 4-HYDROXY-1,5-NAPHTHYRIDINE 4-HYDROXY-1,5-NAPHTHYRIDINE-3-CARBOXYLIC ACID 1,6-Naphthyridine, 2-chloro-5,6,7,8-tetrahydro- 2,7-NAPHTHYRIDINE, 1-CHLORO- 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethyl Ester Nalidixic acid sodium salt 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid

  • 1,8-DIAZANAPHTHALENE
  • 1,8-NAPHTHYRIDINE
  • PYRIDO[2,3-B]PYRIDINE
  • 1,8-Pyridopyridine
  • 1,8-Naphthyridine(6CI,7CI,8CI,9CI)
  • 1,8-NAPHTHYRIDINE 98+%
  • 1,8-Diazanapthalene
  • 1,8-Diazanaphthalene Pyrido[2,3-b]pyridine
  • 1,8-Diazanaphthalene 98%
  • 1,8-Naphthyridine&gt
  • 1, 8 - nalidixic
  • 1,8-NAPHTHYRIDINE ISO 9001：2015 REACH
  • 1,8-Naphthyridine (6CI, 7CI, 8CI, 9CI, ACI)
  • 254-60-4
  • PYRIDINE