ChemicalBook > CAS DataBase List > 1,8-Naphthyridine

1,8-Naphthyridine

Product Name
1,8-Naphthyridine
CAS No.
254-60-4
Chemical Name
1,8-Naphthyridine
Synonyms
1, 8 - nalidixic;1,8-NAPHTHYRIDINE;1,8-Pyridopyridine;1,8-Diazanapthalene;1,8-Naphthyridine>1,8-DIAZANAPHTHALENE;PYRIDO[2,3-B]PYRIDINE;1,8-NAPHTHYRIDINE 98+%;1,8-Diazanaphthalene 98%;1,8-Naphthyridine(6CI,7CI,8CI,9CI)
CBNumber
CB2352000
Molecular Formula
C8H6N2
Formula Weight
130.15
MOL File
254-60-4.mol
More
Less

1,8-Naphthyridine Property

Melting point:
99.8-99.9°C
Boiling point:
248.9±13.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.39
form 
powder to crystal
pka
3.55±0.10(Predicted)
color 
White to Light yellow to Light orange
InChIKey
FLBAYUMRQUHISI-UHFFFAOYSA-N
CAS DataBase Reference
254-60-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2902900000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
N0464
Product name
1,8-Naphthyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$146
Updated
2024/03/01
TCI Chemical
Product number
N0464
Product name
1,8-Naphthyridine
Purity
>98.0%(GC)
Packaging
100mg
Price
$25
Updated
2024/03/01
TRC
Product number
B504303
Product name
1,8-Naphthyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
018153
Product name
[1,8]Naphthyridine
Packaging
500mg
Price
$52
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-DP
Product name
1,8-Diazanaphthalene
Packaging
1g
Price
$150
Updated
2021/12/16
More
Less

1,8-Naphthyridine Chemical Properties,Usage,Production

Description

1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.

Uses

1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands.

Definition

ChEBI: 1,8-naphthyridine is a naphthyridine in which the nitrogens are situated at positions 1 and 8.

Purification Methods

Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.]

1,8-Naphthyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Nalidixic acid
More
Less

1,8-Naphthyridine Suppliers

Americas 1 China 105 Europe 2 France 1 Germany 2 India 3 Japan 1 South Korea 1 Ukraine 1 United Kingdom 7 United States 19 Global 143
Weifang Yuda Pharmaceutical Technology Co., Ltd.
Tel
17663603912
Fax
+86-536- 8637276
Email
2710256076@qq.com
Country
China
ProdList
193
Advantage
56
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Carbott PharmTech Inc.
Tel
0535-6385396
Fax
+86 (535) 638-9971
Email
info@carbottpharm.com
Country
China
ProdList
875
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
shanghai science Bio-Pharmceutical.co,ltd.
Tel
021-021-57872719 13761402923
Fax
02157872719
Email
245662540@qq.com
Country
China
ProdList
308
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18086
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8618575662672 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9742
Advantage
57
Wuhan Taiyicheng Biopharmaceutical Co., Ltd.
Tel
027-88320699
Fax
027-88320962
Email
tycshyy@126.com
Country
China
ProdList
297
Advantage
66
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2867
Advantage
52
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15885
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4901
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7978
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Henan Jiuhua Biological Technology Co., Ltd.
Tel
15738884691 153248764872949584887 237654463
Fax
0371-55320919
Email
jiuhuabiochem@163.com
Country
China
ProdList
2755
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Yantai ShengKailun Chemical Technology Co., Ltd.
Tel
13356901049
Fax
QQ：1025383091
Email
3119594100@qq.com
Country
China
ProdList
8377
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7580
Advantage
55
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9190
Advantage
65
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9970
Advantage
58
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10335
Advantage
58
Wuxi AppTec
Tel
022-59987777 13552403979
Email
jia_guoqiang@wuxiapptec.com
Country
China
ProdList
22346
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 18521078705
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
19983
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15503
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24971
Advantage
58
Zhengzhou Ruke Biological Co., Ltd.
Tel
15981811963
Fax
QQ：1410472904
Email
1410472904@qq.com
Country
China
ProdList
5831
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920564737
Email
sales@heowns.com
Country
China
ProdList
20632
Advantage
60
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20569
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
Advantage
58
More
Less

View Lastest Price from 1,8-Naphthyridine manufacturers

Dideu Industries Group Limited
Product
1,8-NAPHTHYRIDINE 254-60-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-26
Career Henan Chemical Co
Product
1,8-NAPHTHYRIDINE 254-60-4
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2020-01-14

254-60-4, 1,8-NaphthyridineRelated Search:

1,8-Naphthyridine 7,10-dichloro-2-methoxybenzo[b]-1,5-naphthyridine 5,6,7,8-TETRAHYDRO-6-(PHEHYLMETHYL)-1,6-NAPHTHYRIDIN-3-AMINE 3-(CHLOROMETHYL)-6-(TRIFLUOROMETHYL)PYRIDINE 3-ACETYL-2-METHYL-1,6-NAPHTHYRIDINE 3-BROMO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE 2-CHLORO-1,8-NAPHTHYRIDINE 5-Bromo-1,2,3,4-tetrahydro-[1,7]naphthyridine 5-CHLORO-1,6-NAPHTHYRIDINE 5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine 5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDIN-3-OL 4-HYDROXY-1,5-NAPHTHYRIDINE 4-HYDROXY-1,5-NAPHTHYRIDINE-3-CARBOXYLIC ACID 1,6-Naphthyridine, 2-chloro-5,6,7,8-tetrahydro- 2,7-NAPHTHYRIDINE, 1-CHLORO- 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethyl Ester Nalidixic acid sodium salt 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid

  • 1,8-DIAZANAPHTHALENE
  • 1,8-NAPHTHYRIDINE
  • PYRIDO[2,3-B]PYRIDINE
  • 1,8-Pyridopyridine
  • 1,8-Naphthyridine(6CI,7CI,8CI,9CI)
  • 1,8-NAPHTHYRIDINE 98+%
  • 1,8-Diazanapthalene
  • 1,8-Diazanaphthalene Pyrido[2,3-b]pyridine
  • 1,8-Diazanaphthalene 98%
  • 1,8-Naphthyridine&gt
  • 1, 8 - nalidixic
  • 1,8-NAPHTHYRIDINE ISO 9001：2015 REACH
  • 1,8-Naphthyridine (6CI, 7CI, 8CI, 9CI, ACI)
  • 254-60-4
  • PYRIDINE