ChemicalBook > CAS DataBase List > 4-AMINOPYRIDAZINE

4-AMINOPYRIDAZINE

Uses

Product Name: 4-AMINOPYRIDAZINE
CAS No.: 20744-39-2
Chemical Name: 4-AMINOPYRIDAZINE
Synonyms: PYRIDAZIN-4-AMINE;4-Pyridazinamine;4-Aminopyridazin;4-AMINOPYRIDAZINE;PYRIDAZIN-4-YLAMINE;4-Pyridazinamine (9CI, ACI);4-aminopyridazine (MFCD00233975);4-AMinopyridazine pyridazin-4-amine;4-AMINOPYRIDAZINE ISO 9001：2015 REACH;Pyridazin-4-amine, 4-Amino-1,2-diazine
CBNumber: CB2361738
Molecular Formula: C4H5N3
Formula Weight: 95.1
MOL File: 20744-39-2.mol

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4-AMINOPYRIDAZINE Property

Melting point:: 127-133°C
Boiling point:: 326.2±15.0 °C(Predicted)
Density: 1.216±0.06 g/cm3(Predicted)
storage temp.: -20°C
form: solid
pka: 6.38±0.10(Predicted)
color: Light yellow to yellow
InChI: InChI=1S/C4H5N3/c5-4-1-2-6-7-3-4/h1-3H,(H2,5,6)
InChIKey: LUCGBEPEAUHERV-UHFFFAOYSA-N
SMILES: C1=NN=CC=C1N

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 777633
Product name: 4-Aminopyridazine
Purity: 97%
Packaging: 500mg
Price: $50.37
Updated: 2025/07/31

Sigma-Aldrich

Product number: CDS006078
Product name: 4-Aminopyridazine
Purity: AldrichCPR
Packaging: 50mg
Price: $68.1
Updated: 2023/06/20

TRC

Product number: P991295
Product name: 4-Pyridazinamine
Packaging: 1g
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 069821
Product name: 4-Aminopyridazine
Purity: 95%
Packaging: 1g
Price: $39
Updated: 2021/12/16

AK Scientific

Product number: X0249
Product name: 4-Aminopyridazine
Packaging: 1g
Price: $90
Updated: 2021/12/16

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4-AMINOPYRIDAZINE Chemical Properties,Usage,Production

Uses

4-Pyridazinamine is used to prepare phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition. It is also used to synthesize ATP competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors.

Chemical Properties

yellow powder

Uses

Synthesis

823-58-5

20744-39-2

General procedure for the synthesis of 4-aminopyridazine from 3,6-dichloropyridazin-4-amine: 1. 3,6-dichloropyridazin-4-amine (5.00 g, 18.2 mmol) was dissolved in tetrahydrofuran (100 ml), sodium hydroxide (8.00 g, 200 mmol) and water (32 ml) were added. 2. 10% palladium-carbon catalyst (500 mg) was added to the above mixture and the reaction was stirred for 2 days at room temperature under hydrogen atmosphere. 3. After completion of the reaction, the insoluble material was removed by filtration and the filtrate was concentrated. 4. 4. The concentrated residue was dissolved in methanol (100 ml), filtered again to remove the insoluble material, and the filtrate was concentrated to obtain the target product 4-aminopyridazine as a solid. Product characterization: 1H-NMR (DMSO-d6) δ; 2.51 (2H, br s), 6.00 (1H, br s), 7.81-7.85 (1H, m), 7.98-8.00 (1H, m).

References

[1] Patent: EP1813606, 2007, A1. Location in patent: Page/Page column 83-84
[2] Pharmaceutical Bulletin, 1956, vol. 4, p. 137,498
[3] Pharmaceutical Bulletin, 1956, vol. 4, p. 137,498

4-AMINOPYRIDAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-AMINOPYRIDAZINE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Aminopyridazine 20744-39-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10000KG
Release date: 2024-11-09

Shanghai Rlavie Technology Co ltd

Product: 4-AMinopyridazine pyridazin-4-amine 20744-39-2
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 50kgs/month
Release date: 2021-11-13

Dideu Industries Group Limited

Product: 4-AMINOPYRIDAZINE 20744-39-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-01

20744-39-2, 4-AMINOPYRIDAZINERelated Search:

3,6-dichloropyridazin-4-amine 2-Chloro-10-methyl-3,4-diazaphenoxazine Amezinium methylsulfate 3,4-Diaminopyridazine 4-AMINOPYRIDAZINE Azaphen hydrochloride 5-AMINO-3-CHLOROPYRIDAZINE 3-AMINO-6-PHENYLPYRIDAZINE 3,6-Pyridazinediamine(9CI) 6-Chloro-N-cyclopropylpyridazin-3-amine 6-methyl-3-aminopyridazine 3-aminopyridazine-6-carboxylic acid 3-AMINOPYRIDAZINE HYDROCHLORIDE,3-AMINOPYRIDAZINE HYDROCHLORIDE, 97+% 3-AMINOPYRIDAZINE,98.0+%(GC)(T),3-Aminopyridazine 97%,2-AMINOPYRIDAZINE,3-AMINOPYRIDAZINE 6-Chloro-N-methylpyridazin-3-amine 6-chloro-N-pentylpyridazin-3-amine 6-Chloro-N-ethylpyridazin-3-amine PYRIDAZINE-3,4-DIAMINE

4-AMINOPYRIDAZINE

4-Pyridazinamine

PYRIDAZIN-4-AMINE

PYRIDAZIN-4-YLAMINE

4-Aminopyridazin

4-aminopyridazine (MFCD00233975)

Pyridazin-4-amine, 4-Amino-1,2-diazine

4-AMinopyridazine pyridazin-4-amine

4-AMINOPYRIDAZINE ISO 9001：2015 REACH

4-Pyridazinamine (9CI, ACI)

20744-39-2

20744-39-5

Amines

Pyrazines, Pyrimidines & Pyridazines