3-AMINO-6-METHYLPYRIDAZINE

Uses

Product Name: 3-AMINO-6-METHYLPYRIDAZINE
CAS No.: 18591-82-7
Chemical Name: 3-AMINO-6-METHYLPYRIDAZINE
Synonyms: 6-Methylpyridazin-3-amin;3-Ami-6-methylpyridazine;6-Methyl-3-pyridazinamine;6-METHYLPYRIDAZIN-3-AMINE;3-AMINO-6-METHYLPYRIDAZINE;6-methyl-3-aminopyridazine;3-PyridazinaMine, 6-Methyl-;6-methylpyridazine-3-ylamine;3-Amino-6-methylpyridazin...;6-Methylpyridazin-3-amine, tech
CBNumber: CB8156118
Molecular Formula: C5H7N3
Formula Weight: 109.13
MOL File: 18591-82-7.mol

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3-AMINO-6-METHYLPYRIDAZINE Property

Melting point:: 222-223℃
Boiling point:: 319℃
Density: 1.155
Flash point:: 173℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 5.48±0.10(Predicted)
color: very dark red/brown
InChI: InChI=1S/C5H7N3/c1-4-2-3-5(6)8-7-4/h2-3H,1H3,(H2,6,8)
InChIKey: KAZMCIGKULUUMR-UHFFFAOYSA-N
SMILES: C1(N)=NN=C(C)C=C1

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Safety

Hazard Codes: Xn
Risk Statements: 22
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: A576713
Product name: 3-Amino-6-methylpyridazine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-1-V7
Product name: 3-Amino-6-methylpyridazine
Packaging: 1g
Price: $58
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-1-V7
Product name: 3-Amino-6-methylpyridazine
Packaging: 5G
Price: $208
Updated: 2021/12/16

Matrix Scientific

Product number: 068663
Product name: 3-Amino-6-methylpyridazine
Purity: >95%
Packaging: 5g
Price: $475
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-1-V7
Product name: 3-Amino-6-methylpyridazine
Packaging: 25g
Price: $576
Updated: 2021/12/16

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3-AMINO-6-METHYLPYRIDAZINE Chemical Properties,Usage,Production

Uses

Pyridazines are an important class of aromatic heterocyclic compounds with strong antiviral, hypotensive, cardiotonic, and anticancer physiological activities. 6-Methyl-3-aminopyridazine is a heterocyclic organic compound and can be used as a very important pharmaceutical and chemical intermediate.

Synthesis

1121-79-5

18591-87-2

Step A: A mixture of 3-chloro-6-methylpyridazine (516 mg, 4.0 mmol), NH4OH (30%, 3 mL), and copper(II) sulfate pentahydrate (26 mg, 0.2 mmol) was stirred for 40 hours at 120 °C. After completion of the reaction, the mixture was cooled to room temperature and partitioned between EtOAc and brine. The aqueous layer was extracted five times with EtOAc. The combined organic phases were dried with anhydrous Na2SO4, filtered and concentrated, and purified by silica gel column chromatography (elution gradient: 0-10% MeOH in CH2Cl2 solution) to afford 6-methylpyridazin-3-amine (160 mg, 37% yield) as a white solid. ms m/z 109.9 [M + H]+.

References

[1] Patent: US9617268, 2017, B2. Location in patent: Page/Page column 386; 387
[2] Patent: WO2006/102194, 2006, A1. Location in patent: Page/Page column 25
[3] Patent: WO2006/107784, 2006, A1. Location in patent: Page/Page column 33
[4] Chemische Berichte, 1948, vol. 81, p. 1,10
[5] Journal of the Chemical Society, 1947, p. 239,242

3-AMINO-6-METHYLPYRIDAZINE Preparation Products And Raw materials

Raw materials

Hexane Ammonium hydroxide Hydrazinium hydroxide solution Nitrogen Levulinic acid Toluene Phosphorus oxitrichloride Ethyl acetate Sodium bicarbonate Bromine Dichloromethane Acetic acid Methanol Sodium hydroxide Isopropyl alcohol

Preparation Products

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3-AMINO-6-METHYLPYRIDAZINE Suppliers

China 147 France 1 Germany 1 India 3 United Kingdom 2 United States 16 Global 170

Wuhan Luohua Medical Technology Co.,Ltd.

Tel: 13477084141; 13477084141
Fax: +86(27)65566697
Email: sales@luohuapharm.com
Country: China
ProdList: 468
Advantage: 60

Zhengzhou Ailfield Chemical Co., Ltd.

Tel: 0311-84468392; 15993358503
Email: 1013053532@qq.com
Country: China
ProdList: 254
Advantage: 58

Nanjing Jubai Biomedical Technology Co., Ltd.

Tel: 13585203734
Email: info@jbzml.com
Country: China
ProdList: 99
Advantage: 58

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 918
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279
Fax: QQ：14057904
Email: sales@shydchem.com.cn
Country: China
ProdList: 998
Advantage: 56

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

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View Lastest Price from 3-AMINO-6-METHYLPYRIDAZINE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 6-Methyl-3-pyridazinamine 18591-82-7
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-02

Shanghai Rlavie Technology Co ltd

Product: 6-methylpyridazin-3-amine 18591-82-7
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

Dideu Industries Group Limited

Product: 3-AMINO-6-METHYLPYRIDAZINE 18591-82-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-02

18591-82-7, 3-AMINO-6-METHYLPYRIDAZINERelated Search:

3-Amino-6-morpholin-4-ylpyridazine 3-Pyridazinecarbonitrile,6-amino-(9CI) 3-AMINO-6-PHENYLPYRIDAZINE 3-Amino-6-ethylpyridine-4-boronic acid pinacol ester 6-ETHYL-PYRIDAZIN-3-YLAMINE 3-Amino-6-bromopyridazine-4,5-d2 3-Amino-6-methylpyridine-4-boronic acid pinacol ester MINAPRINE DIHYDROCHLORIDE MY-5445 3-Methylpyridazin-6-ylhydrazine 3-METHYL-6-(1-METHYLHYDRAZINO)PYRIDAZINE SR-95531 3-(2-FLUOROBENZYL)-6-HYDRAZINOPYRIDAZINE 1-BENZYL-4-MORPHOLINOPHTHALAZINE 1-[6-(2,4-DICHLOROBENZYL)-3-PYRIDAZINYL]-4-PHENYL-1H-PYRAZOL-5-AMINE N-(4-BENZYL-1-PHTHALAZINYL)-N-[3-(DIMETHYLAMINO)PROPYL]AMINE 1-[6-(2,4-DICHLOROBENZYL)-3-PYRIDAZINYL]-4-(4-FLUOROPHENYL)-1H-PYRAZOL-5-AMINE 2-(6-ANILINO-3-PYRIDAZINYL)-2-(2,4-DICHLOROPHENYL)ACETONITRILE

6-METHYLPYRIDAZIN-3-AMINE

3-Ami-6-methylpyridazine

6-methylpyridazine-3-ylamine

3-AMINO-6-METHYLPYRIDAZINE

6-Methylpyridazin-3-amine, tech

6-methyl-3-aminopyridazine

6-Methyl-3-pyridazinamine

3-Amino-6-methylpyridazin...

3-PyridazinaMine, 6-Methyl-

6-Methylpyridazin-3-amine, 3-Amino-6-methyl-1,2-diazine

6-Methylpyridazin-3-amin

3-AMINO-6-METHYLPYRIDAZINE ISO 9001：2015 REACH

18591-82-7

Pyrazines, Pyrimidines & Pyridazines

Amines

Pyrazines, Pyrimidines & Pyridazines