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MY-5445

Product Name
MY-5445
CAS No.
78351-75-4
Chemical Name
MY-5445
Synonyms
MY-5445;MY 5445;MY5445;1-(3-CHLOROANILINO)-4-PHENYLPHTHALAZINE;1-(3-Chloroanilino)-4-phenylphthalazine >1-(3-CHLOROPHENYLAMINO)-4-PHENYLPHTHALAZINE;N-(3-chlorophenyl)-4-phenylphthalazin-1-amine;N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine;1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-;aggregation,platelet,Inhibitor,anticancer,inhibit,MY5445,neuropathic,MY 5445,Phosphodiesterase (PDE),neuropathic pain,allodynia,MY-5445
CBNumber
CB9739543
Molecular Formula
C20H14ClN3
Formula Weight
331.8
MOL File
78351-75-4.mol
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MY-5445 Property

Boiling point:
539.7±50.0 °C(Predicted)
Density 
1.310±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
DMF: 2 mg/ml; DMSO: 2 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
pka
4.91±0.30(Predicted)
form 
Yellow solid.
color 
White to Light yellow
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
HS Code 
2933.99.8290
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2884
Product name
1-(3-Chloroanilino)-4-phenylphthalazine
Purity
>98.0%(GC)
Packaging
20mg
Price
$105
Updated
2024/03/01
TCI Chemical
Product number
C2884
Product name
1-(3-Chloroanilino)-4-phenylphthalazine
Purity
>98.0%(GC)
Packaging
100mg
Price
$358
Updated
2024/03/01
Cayman Chemical
Product number
20872
Product name
MY-5445
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20872
Product name
MY-5445
Purity
≥98%
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
20872
Product name
MY-5445
Purity
≥98%
Packaging
10mg
Price
$153
Updated
2024/03/01
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MY-5445 Chemical Properties,Usage,Production

Description

MY-5445 is a selective inhibitor of the cyclic GMP (cGMP) phosphodiesterase, PDE5, with a Ki value of 1.3 μM. It inhibits calcium- and cAMP-selective PDEs with Ki values of >1,000 and 915 μM, respectively. MY-5445 has been shown to relax intact strips of rat aorta with an EC50 value of 4 μM.

Uses

MY-5445 is a selective cGMP phosphodiesterase inhibitor. Potent PDE5 inhibitor.

Definition

ChEBI: N-(3-chlorophenyl)-4-phenyl-1-phthalazinamine is a ring assembly and a member of pyridazines.

Biological Activity

Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC 50 = 0.5 μ M).

MY-5445 Preparation Products And Raw materials

Raw materials

Preparation Products

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MY-5445 Suppliers

Americas 1 China 56 Europe 1 Germany 2 India 1 Italy 1 Japan 3 Switzerland 2 United Kingdom 3 United States 19 Global 89
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
sales@zhiwe.net
Country
China
ProdList
607
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60

78351-75-4, MY-5445Related Search:

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  • MY-5445
  • 1-(3-CHLOROPHENYLAMINO)-4-PHENYLPHTHALAZINE
  • 1-(3-CHLOROANILINO)-4-PHENYLPHTHALAZINE
  • N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine
  • N-(3-chlorophenyl)-4-phenylphthalazin-1-amine
  • MY 5445;MY5445
  • 1-(3-Chloroanilino)-4-phenylphthalazine &gt
  • aggregation,platelet,Inhibitor,anticancer,inhibit,MY5445,neuropathic,MY 5445,Phosphodiesterase (PDE),neuropathic pain,allodynia,MY-5445
  • 1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-
  • 78351-75-4
  • C20H14ClN3
  • Cyclic Nucleotide related