MY-5445

ChemicalBook > CAS DataBase List > MY-5445

Product Name: MY-5445
CAS No.: 78351-75-4
Chemical Name: MY-5445
Synonyms: MY-5445;MY 5445;MY5445;MY-5445, 10 mM in DMSO;1-(3-CHLOROANILINO)-4-PHENYLPHTHALAZINE;1-(3-Chloroanilino)-4-phenylphthalazine >1-(3-CHLOROPHENYLAMINO)-4-PHENYLPHTHALAZINE;N-(3-chlorophenyl)-4-phenylphthalazin-1-amine;N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine;1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-;aggregation,platelet,Inhibitor,anticancer,inhibit,MY5445,neuropathic,MY 5445,Phosphodiesterase (PDE),neuropathic pain,allodynia,MY-5445
CBNumber: CB9739543
Molecular Formula: C20H14ClN3
Formula Weight: 331.8
MOL File: 78351-75-4.mol

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MY-5445 Property

Boiling point:: 539.7±50.0 °C(Predicted)
Density: 1.310±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: DMF: 2 mg/ml; DMSO: 2 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
pka: 4.91±0.30(Predicted)
form: Yellow solid.
color: White to Light yellow

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
HS Code: 2933.99.8290

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2884
Product name: 1-(3-Chloroanilino)-4-phenylphthalazine
Purity: >98.0%(GC)
Packaging: 20mg
Price: $105
Updated: 2024/03/01

TCI Chemical

Product number: C2884
Product name: 1-(3-Chloroanilino)-4-phenylphthalazine
Purity: >98.0%(GC)
Packaging: 100mg
Price: $358
Updated: 2024/03/01

Cayman Chemical

Product number: 20872
Product name: MY-5445
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20872
Product name: MY-5445
Purity: ≥98%
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 20872
Product name: MY-5445
Purity: ≥98%
Packaging: 10mg
Price: $153
Updated: 2024/03/01

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MY-5445 Chemical Properties,Usage,Production

Description

MY-5445 is a selective inhibitor of the cyclic GMP (cGMP) phosphodiesterase, PDE5, with a K_i value of 1.3 μM. It inhibits calcium- and cAMP-selective PDEs with K_i values of >1,000 and 915 μM, respectively. MY-5445 has been shown to relax intact strips of rat aorta with an EC₅₀ value of 4 μM.

Uses

MY-5445 is a selective cGMP phosphodiesterase inhibitor. Potent PDE5 inhibitor.

Definition

ChEBI: N-(3-chlorophenyl)-4-phenyl-1-phthalazinamine is a ring assembly and a member of pyridazines.

Biological Activity

Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC 50 = 0.5 μ M).

MY-5445 Preparation Products And Raw materials

Raw materials

Preparation Products

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MY-5445 Suppliers

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78351-75-4, MY-5445Related Search:

ZARDAVERINE RO 20-1724 BRL 50481 Vinpocetine ZAPRINAST ROLIPRAM Cilostazol (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE CILOSTAMIDE EHNA HYDROCHLORIDE 3-AMINO-6-METHYLPYRIDAZINE AKOS BB-5445 3-AMINO-6-PHENYLPYRIDAZINE MY-5445 1-AMINOPHTHALAZINE RARECHEM AK PP 5445 AURORA KA-5445 AURORA 5445

MY-5445

1-(3-CHLOROPHENYLAMINO)-4-PHENYLPHTHALAZINE

1-(3-CHLOROANILINO)-4-PHENYLPHTHALAZINE

N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine

N-(3-chlorophenyl)-4-phenylphthalazin-1-amine

MY 5445;MY5445

1-(3-Chloroanilino)-4-phenylphthalazine &gt

aggregation,platelet,Inhibitor,anticancer,inhibit,MY5445,neuropathic,MY 5445,Phosphodiesterase (PDE),neuropathic pain,allodynia,MY-5445

1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-

MY-5445, 10 mM in DMSO

78351-75-4

C20H14ClN3

Cyclic Nucleotide related