4-Hydroxyquinoline

Product Name: 4-Hydroxyquinoline
CAS No.: 611-36-9
Chemical Name: 4-Hydroxyquinoline
Synonyms: KYNURINE;AKOS 222-32;4-QUINOLINOL;QUINOLIN-4-OL;4-HydroxyquinoL;4-Quinolinol 98%;4-Quinolinol >1H-Quinolin-4-one;4(1H)-QUINOLINONE;4-hydroxy-quinolin
CBNumber: CB2372460
Molecular Formula: C9H7NO
Formula Weight: 145.16
MOL File: 611-36-9.mol

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4-Hydroxyquinoline Property

Melting point:: 200-202 °C(lit.)
Boiling point:: 264.27°C (rough estimate)
Density: 1.1555 (rough estimate)
refractive index: 1.4500 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in methanol.
form: Crystalline Powder or Needles
pka: 2.23, 11.28(at 20℃)
color: Light beige to yellow
Water Solubility: 4.8g/L(15 ºC)
BRN: 1524969
InChI: 1S/C9H7NO/c11-9-5-6-10-8-4-2-1-3-7(8)9/h1-6H,(H,10,11)
InChIKey: PMZDQRJGMBOQBF-UHFFFAOYSA-N
SMILES: Oc1ccnc2ccccc12
LogP: 2.450 (est)
CAS DataBase Reference: 611-36-9(CAS DataBase Reference)
NIST Chemistry Reference: 4-Quinolinol(611-36-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: VC4070000
HS Code: 29334900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H58005
Product name: 4-Quinolinol
Purity: 98%
Packaging: 1g
Price: $26.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: H58005
Product name: 4-Quinolinol
Purity: 98%
Packaging: 5g
Price: $123
Updated: 2025/07/31

TCI Chemical

Product number: Q0029
Product name: 4-Quinolinol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $63
Updated: 2025/07/31

TCI Chemical

Product number: Q0029
Product name: 4-Quinolinol
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $249
Updated: 2025/07/31

Sigma-Aldrich

Product number: H58005
Product name: 4-Quinolinol
Purity: 98%
Packaging: 10g
Price: $192
Updated: 2025/07/31

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4-Hydroxyquinoline Chemical Properties,Usage,Production

Description

4-Hydroxyquinoline is a quinoline alkaloid that has been found in Z. lotus honeys. It is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules such as 2-heptyl-3-hydroxy-4(1H)-quinolone and 2-nonyl-3-hydroxy-4-quinolone. 4-Hydroxyquinoline has been used as a precursor in the synthesis of compounds with antibacterial activity. It has also been used as a fluorescent detection reagent for iron(III) in bovine liver samples.

Chemical Properties

LIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES

Uses

4-Hydroxyquinolineis is a raw material in medical research, a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.

Definition

ChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1264, 1946 DOI: 10.1021/ja01211a038

General Description

4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.

Biological Activity

4-hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity. it shows growth-inhibitory effects against intestinal bacteria. it also can be used as sacrificial scavengers of the photogenerated oxygen species.

References

[1] F. KHALLOUKI. HPLC-ESI-MS and GC-EI-MS Identification and Quantitation of Polyphenolics and Alkaloids in Moroccan Jujube Honeys[J]. Journal of Apicultural Science, 2020, 64 1: 287-299. DOI: 10.2478/jas-2020-0029
[2] STEPHAN HEEB. Quinolones: from antibiotics to autoinducers[J]. FEMS microbiology reviews, 2011, 35 2: 247-274. DOI: 10.1111/j.1574-6976.2010.00247.x
[3] MARIE-GRATIA KAYIRERE . Synthesis and antibacterial activity of new 4-alkoxy, 4-aminoalkyl and 4-alkylthioquinoline derivatives[J]. European Journal of Medicinal Chemistry, 1998, 33 1: Pages 55-63. DOI: 10.1016/s0223-5234(99)80076-2
[4] GEORGE C. RAGOS Prodromos B I Mavroudis A Demertzis. A high-sensitive spectrofluorimetric method for the determination of micromolar concentrations of iron(III) in bovine liver with 4-hydroxyquinoline[J]. Farmaco (Societa chimica italiana?: 1989), 1998, 53 8: Pages 611-616. DOI: 10.1016/s0014-827x(98)00070-6

4-Hydroxyquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

4-Chloroquinoline Disperse Yellow HG Imiquimod 4-AMINO-3-NITROQUINOLINE 3,4-DIAMINOQUINOLINE DECAHYDRO-QUINOLIN-4-OL HYDROCHLORIDE 3-NITRO-4-QUINOLINOL 4-Chloro-3-nitroquinoline

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4-Hydroxyquinoline Suppliers

Austria 1 Belgium 3 Canada 1 China 359 Europe 2 France 3 Germany 9 India 27 Japan 4 Switzerland 2 Ukraine 1 United Kingdom 16 United States 55 USA 1 Global 484

Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd.

Tel: 18606289633 15862625988
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Changzhou Anchor Biological Technology Co., Ltd

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Shanghai yongzeng technology co., LTD

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Jinan Chengquan Chemical Co., Ltd

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Anhui Shuangmai Intelligent Technology Co., LTD

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CHANGZHOU GARDE PHARMTECH CO.,LTD

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Yantai Xianhua Chemical Technology Co., Ltd (HSBC Shandong Yantai Fine Chemical Co., Ltd.)

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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INTATRADE GmbH

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Email: sales@intatrade.de
Country: Germany
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View Lastest Price from 4-Hydroxyquinoline manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 4-Hydroxyquinoline 611-36-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2026-01-17

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Hydroxyquinoline 611-36-9
Price: US $10.00-8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-05

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Hydroxyquinoline 611-36-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-28

611-36-9, 4-HydroxyquinolineRelated Search:

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QUINOLIN-4-OL

QUINOLIN-4(1H)-ONE

KYNURINE

4-hydroxy-quinolin

1H-Quinolin-4-one

Quinoline, 4-hydroxy-

4-Hydroxyquinoline98%

4-Quinolinol,4-Hydroxyquinoline

4-Hydroxyquinoline, 98% 10GR

4-hydroxyquatolate

4-Quinolinol 98%

4(1H)-QUINOLINONE

4-QUINOLINOL

4-HYDROXYQUINOLINE

4-HYDROXY-1-AZANAPHTHALENE

HYDROXYQUINOLINE,4-

4-Hydroxyquinoline, >=98.5%

AKOS 222-32

4-Quinolinol &gt

4-HydroxyquinoL

4-Hydroxyquinoline ISO 9001：2015 REACH

Bedaquiline Impurity 15

4-Hydroxyquinoline, 10 mM in DMSO

4-Hydroxyquinoline, 95%

4-Hydroxyquinoline-d6

2-(3-((1R,2S)-4-(dimethylamino)-2-hydroxy-2-(naphthalen-1-yl)-1-phenylbutyl)-2-methoxyquinolin-6-yl)fumaric acid

611-36-9

C9H8NO

ALCOHOL

Hydroxyquinolines

Quinolines

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C8 to C10

Chemical Synthesis

Heterocyclic Building Blocks

Quinoline&Isoquinoline

Quinolines

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quinoline

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