ChemicalBook > CAS DataBase List > 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

Product Name
6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
CAS No.
328956-08-7
Chemical Name
6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
Synonyms
6-Fluoro-4-(trifluoromethyl)quinolin-2-ol;6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone;6-fluoro-4-(trifluoromethyl)-1H-quinolin-2-one;6-Fluoro-4-(trifluoroMethyl)quinolin-2(1H)-one;6-Fluoro-4-(trifluoromethyl)quinolin-2-ol ,97%;2(1H)-Quinolinone, 6-fluoro-4-(trifluoromethyl)-;6-Fluoro-2-hydroxy-4-(trifluoroMethyl)quinoline, 97%
CBNumber
CB92128695
Molecular Formula
C10H5F4NO
Formula Weight
231.15
MOL File
328956-08-7.mol
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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Property

Melting point:
252-253 °C (decomp)(Solv: ethanol (64-17-5))
Boiling point:
282 ºC
Density 
1.468
Flash point:
124 ºC
storage temp. 
2-8°C
pka
9.33±0.70(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C10H5F4NO/c11-5-1-2-8-6(3-5)7(10(12,13)14)4-9(16)15-8/h1-4H,(H,15,16)
InChIKey
WUFRBOSKPZUGIS-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(F)C=C2)C(C(F)(F)F)=CC1=O
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
Z3039
Product name
6-Fluoro-4-(trifluoromethyl)quinolin-2-ol
Packaging
1g
Price
$248
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0044205
Product name
6-FLUORO-4-(TRIFLUOROMETHYL)QUINOLIN-2-OL
Purity
95.00%
Packaging
5MG
Price
$502.41
Updated
2021/12/16
Chemenu
Product number
CM145793
Product name
6-Fluoro-4-(trifluoromethyl)quinolin-2-ol
Purity
97%
Packaging
5g
Price
$561
Updated
2021/12/16
Alichem
Product number
328956087
Product name
6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
Packaging
5g
Price
$570.32
Updated
2021/12/16
Crysdot
Product number
CD11144361
Product name
6-Fluoro-4-(trifluoromethyl)quinolin-2(1H)-one
Purity
97%
Packaging
5g
Price
$594
Updated
2021/12/16
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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Chemical Properties,Usage,Production

Chemical Properties

White solid

Description

As a quinoline derivative, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline is substituted with trifluoromethyl, hydroxyl, and fluoride groups. In particular, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline can exist in a tautomeric form, known as quinolone, where the hydroxy group becomes a ketone and the imine changes to an amine. This compound is a precursor for synthesizing thioquinolines, which are used to develop non-cytotoxic, potent and selective antitubercular agents. The thiolation reaction is carried out using phosphorus pentasulfide in pyridine.

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

Ethyl 4,4,4-trifluoroacetoacetate 4-Fluoroaniline Sulfuric acid

Preparation Products

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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Suppliers

China 54 India 1 United States 8 Global 63
Suzhouhongxiong
Tel
18051745768 18051745768;
Email
Suzhouhongxiong@163.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
ProdList
30123
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
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Nanjing Habo Medical Technology Co., Ltd.
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13376080562 13376090521
Fax
025-85766769
Email
sales@habotech.com
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China
ProdList
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Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
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China
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Chiba Pharmaceutical Science and technology Co, Ltd.
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0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
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China
ProdList
3989
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Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
ProdList
3997
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Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
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55
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View Lastest Price from 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone manufacturers

Career Henan Chemical Co
Product
6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone 328956-08-7
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200KG
Release date
2018-12-23

328956-08-7, 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinoneRelated Search:

Trifluoromethanesulfonic acid 3-Aminobenzotrifluoride 3-(Trifluoromethyl)benzaldehyde (Trifluoromethyl)trimethylsilane 2-(Trifluoromethyl)benzoic acid 2-Methylbenzotrifluoride 2-(Trifluoromethyl)benzyl chloride 6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97% 2-Hydroxy-4-(trifluoromethyl)quinoline Fluorine 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

  • 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
  • 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol
  • 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol ,97%
  • 6-Fluoro-2-hydroxy-4-(trifluoroMethyl)quinoline, 97%
  • 6-Fluoro-4-(trifluoroMethyl)quinolin-2(1H)-one
  • 6-fluoro-4-(trifluoromethyl)-1H-quinolin-2-one
  • 2(1H)-Quinolinone, 6-fluoro-4-(trifluoromethyl)-
  • 328956-08-7