6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

ChemicalBook > CAS DataBase List > 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

Product Name: 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
CAS No.: 328956-08-7
Chemical Name: 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
Synonyms: 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol;6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone;6-fluoro-4-(trifluoromethyl)-1H-quinolin-2-one;6-Fluoro-4-(trifluoroMethyl)quinolin-2(1H)-one;6-Fluoro-4-(trifluoromethyl)quinolin-2-ol ,97%;2(1H)-Quinolinone, 6-fluoro-4-(trifluoromethyl)-;6-Fluoro-2-hydroxy-4-(trifluoroMethyl)quinoline, 97%
CBNumber: CB92128695
Molecular Formula: C10H5F4NO
Formula Weight: 231.15
MOL File: 328956-08-7.mol

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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Property

Melting point:: 252-253 °C (decomp)(Solv: ethanol (64-17-5))
Boiling point:: 282 ºC
Density: 1.468
Flash point:: 124 ºC
storage temp.: 2-8°C
pka: 9.33±0.70(Predicted)
InChI: InChI=1S/C10H5F4NO/c11-5-1-2-8-6(3-5)7(10(12,13)14)4-9(16)15-8/h1-4H,(H,15,16)
InChIKey: WUFRBOSKPZUGIS-UHFFFAOYSA-N
SMILES: N1C2=C(C=C(F)C=C2)C(C(F)(F)F)=CC1=O

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific

Product number: Z3039
Product name: 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol
Packaging: 1g
Price: $248
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0044205
Product name: 6-FLUORO-4-(TRIFLUOROMETHYL)QUINOLIN-2-OL
Purity: 95.00%
Packaging: 5MG
Price: $502.41
Updated: 2021/12/16

Chemenu

Product number: CM145793
Product name: 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol
Purity: 97%
Packaging: 5g
Price: $561
Updated: 2021/12/16

Alichem

Product number: 328956087
Product name: 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
Packaging: 5g
Price: $570.32
Updated: 2021/12/16

Crysdot

Product number: CD11144361
Product name: 6-Fluoro-4-(trifluoromethyl)quinolin-2(1H)-one
Purity: 97%
Packaging: 5g
Price: $594
Updated: 2021/12/16

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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Chemical Properties,Usage,Production

Chemical Properties

White solid

Description

As a quinoline derivative, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline is substituted with trifluoromethyl, hydroxyl, and fluoride groups. In particular, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline can exist in a tautomeric form, known as quinolone, where the hydroxy group becomes a ketone and the imine changes to an amine. This compound is a precursor for synthesizing thioquinolines, which are used to develop non-cytotoxic, potent and selective antitubercular agents. The thiolation reaction is carried out using phosphorus pentasulfide in pyridine.

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

Ethyl 4,4,4-trifluoroacetoacetate 4-Fluoroaniline Sulfuric acid

Preparation Products

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View Lastest Price from 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone manufacturers

Career Henan Chemical Co

Product: 6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone 328956-08-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200KG
Release date: 2018-12-23

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