2-Hydroxy-4-(trifluoromethyl)quinoline
- Product Name
- 2-Hydroxy-4-(trifluoromethyl)quinoline
- CAS No.
- 25199-84-2
- Chemical Name
- 2-Hydroxy-4-(trifluoromethyl)quinoline
- Synonyms
- BUTTPARK 33\04-80;4-(Trifluoromethyl)quinolin-2-ol;4-Trifluoromethyl-1H-quinolin-2-one;4-trifluoroMethyl-2(1H)-quinolinone;4-(trifluoromethyl)quinolin-2(1H)-one;2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE;4--(TrifluoroMethyl)quinoline-2(H)-one;2-hydroxy-4-(trifluoroMethyl)quinqline;4-Trifluoromethyl-2(1H)-quinolinone,97%;2(1H)-Quinolinone, 4-(trifluoromethyl)-
- CBNumber
- CB0496696
- Molecular Formula
- C10H6F3NO
- Formula Weight
- 213.16
- MOL File
- 25199-84-2.mol
2-Hydroxy-4-(trifluoromethyl)quinoline Property
- Melting point:
- >240°C
- Boiling point:
- 284 ºC
- Density
- 1.391
- Flash point:
- 126 ºC
- storage temp.
- Sealed in dry,Room Temperature
- form
- Solid
- color
- White
- InChI
- InChI=1S/C10H6F3NO/c11-10(12,13)7-5-9(15)14-8-4-2-1-3-6(7)8/h1-5H,(H,14,15)
- InChIKey
- UUROBWTVZZNDFD-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)C(C(F)(F)F)=CC1=O
- CAS DataBase Reference
- 25199-84-2
Safety
- Safety Statements
- 24/25
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H61732
- Product name
- 4-Trifluoromethyl-2(1H)-quinolinone, 97%
- Packaging
- 1g
- Price
- $264
- Updated
- 2024/03/01
- Product number
- H61732
- Product name
- 4-Trifluoromethyl-2(1H)-quinolinone, 97%
- Packaging
- 250mg
- Price
- $92.2
- Updated
- 2023/06/20
- Product number
- T900055
- Product name
- 4-(trifluoromethyl)quinolin-2(1H)-one
- Packaging
- 50mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 074152
- Product name
- 2-Hydroxy-4-(trifluoromethyl)quinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $416
- Updated
- 2021/12/16
- Product number
- 37718
- Product name
- 2-Hydroxy-4-(trifluoromethyl)quinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $447
- Updated
- 2021/12/16
2-Hydroxy-4-(trifluoromethyl)quinoline Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
4-Trifluoromethylquinolin-2(1H)-one was prepared by reacting aniline and ethyl-4,4,4-trifluoroacetoacetate stirred in toluene.
Experimental Procedure: In a 1 L round flask fitted with a reflux condenser a mixture of 25.60 g aniline, 50.0 g ethyl-4,4,4-trifluoroacetoacetate 300 ml toluene was heated to reflux in an oil bath at 130 °C. After 20 min 3 ml water was added and the mixture was heated at reflux for another 24 h. the reaction mixture was cooled to room temperature and concentrated under reduced pressure. A round flask with 200 mL H2SO4 was heated to 80°C and the crude oil from the step before was added in portions to the H2SO4 keeping the internal temperature below 90°C, total addition time was approximately 40 min. After addition was complete, the mixture was stirred at 80°C for 1 h, cooled and poured onto 400 g crushed ice. The resulting solids were filtered, washed with water, and dried under vacuum at 40°C to give 33.0 g (50%) product (2-Hydroxy-4-(trifluoromethyl)quinoline) as a colorless solid.
2-Hydroxy-4-(trifluoromethyl)quinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Hydroxy-4-(trifluoromethyl)quinoline manufacturers
- Product
- 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE 25199-84-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-12-23