ChemicalBook > CAS DataBase List > 2-Hydroxy-4-(trifluoromethyl)quinoline

2-Hydroxy-4-(trifluoromethyl)quinoline

Product Name
2-Hydroxy-4-(trifluoromethyl)quinoline
CAS No.
25199-84-2
Chemical Name
2-Hydroxy-4-(trifluoromethyl)quinoline
Synonyms
BUTTPARK 33\04-80;4-(Trifluoromethyl)quinolin-2-ol;4-Trifluoromethyl-1H-quinolin-2-one;4-trifluoroMethyl-2(1H)-quinolinone;4-(trifluoromethyl)quinolin-2(1H)-one;2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE;4--(TrifluoroMethyl)quinoline-2(H)-one;2-hydroxy-4-(trifluoroMethyl)quinqline;4-Trifluoromethyl-2(1H)-quinolinone,97%;2(1H)-Quinolinone, 4-(trifluoromethyl)-
CBNumber
CB0496696
Molecular Formula
C10H6F3NO
Formula Weight
213.16
MOL File
25199-84-2.mol
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2-Hydroxy-4-(trifluoromethyl)quinoline Property

Melting point:
>240°C
Boiling point:
284 ºC
Density 
1.391
Flash point:
126 ºC
storage temp. 
Sealed in dry,Room Temperature
form 
Solid
color 
White
InChI
InChI=1S/C10H6F3NO/c11-10(12,13)7-5-9(15)14-8-4-2-1-3-6(7)8/h1-5H,(H,14,15)
InChIKey
UUROBWTVZZNDFD-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2)C(C(F)(F)F)=CC1=O
CAS DataBase Reference
25199-84-2
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Safety

Safety Statements 
24/25
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H61732
Product name
4-Trifluoromethyl-2(1H)-quinolinone, 97%
Packaging
1g
Price
$264
Updated
2024/03/01
Alfa Aesar
Product number
H61732
Product name
4-Trifluoromethyl-2(1H)-quinolinone, 97%
Packaging
250mg
Price
$92.2
Updated
2023/06/20
TRC
Product number
T900055
Product name
4-(trifluoromethyl)quinolin-2(1H)-one
Packaging
50mg
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
074152
Product name
2-Hydroxy-4-(trifluoromethyl)quinoline
Purity
95+%
Packaging
1g
Price
$416
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
37718
Product name
2-Hydroxy-4-(trifluoromethyl)quinoline
Purity
95+%
Packaging
1g
Price
$447
Updated
2021/12/16
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2-Hydroxy-4-(trifluoromethyl)quinoline Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

4-Trifluoromethylquinolin-2(1H)-one was prepared by reacting aniline and ethyl-4,4,4-trifluoroacetoacetate stirred in toluene.
Experimental Procedure: In a 1 L round flask fitted with a reflux condenser a mixture of 25.60 g aniline, 50.0 g ethyl-4,4,4-trifluoroacetoacetate 300 ml toluene was heated to reflux in an oil bath at 130 °C. After 20 min 3 ml water was added and the mixture was heated at reflux for another 24 h. the reaction mixture was cooled to room temperature and concentrated under reduced pressure. A round flask with 200 mL H2SO4 was heated to 80°C and the crude oil from the step before was added in portions to the H2SO4 keeping the internal temperature below 90°C, total addition time was approximately 40 min. After addition was complete, the mixture was stirred at 80°C for 1 h, cooled and poured onto 400 g crushed ice. The resulting solids were filtered, washed with water, and dried under vacuum at 40°C to give 33.0 g (50%) product (2-Hydroxy-4-(trifluoromethyl)quinoline) as a colorless solid.

2-Hydroxy-4-(trifluoromethyl)quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Hydroxy-4-(trifluoromethyl)quinoline Suppliers

Suzhouhongxiong
Tel
18051745768 18051745768
Email
Suzhouhongxiong@163.com
Country
China
ProdList
70
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58
Jointpharma Technology Co.Ltd
Tel
021-61150629 +86-15921749159
Email
dongshengxie@aliyun.com
Country
China
ProdList
345
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58
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
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568470422@qq.com
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China
ProdList
10024
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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84
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
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Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.
Tel
21-54820552
Fax
086-21-64964478
Email
188738128@qq.com
Country
China
ProdList
309
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66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
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60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
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View Lastest Price from 2-Hydroxy-4-(trifluoromethyl)quinoline manufacturers

Career Henan Chemical Co
Product
2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE 25199-84-2
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200KG
Release date
2018-12-23

25199-84-2, 2-Hydroxy-4-(trifluoromethyl)quinolineRelated Search:


  • BUTTPARK 33\04-80
  • 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
  • 4-(Trifluoromethyl)quinolin-2-ol
  • 4-Trifluoromethyl-1H-quinolin-2-one
  • 2-Hydroxy-4-(trifluoromethyl)quinoline ,98%
  • 4-(trifluoromethyl)quinolin-2(1H)-one
  • 2-hydroxy-4-(trifluoroMethyl)quinqline
  • 4--(TrifluoroMethyl)quinoline-2(H)-one
  • 4-trifluoroMethyl-2(1H)-quinolinone
  • 2(1H)-Quinolinone, 4-(trifluoromethyl)-
  • 4-Trifluoromethyl-2(1H)-quinolinone,97%
  • 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE ISO 9001:2015 REACH
  • 25199-84-2
  • C10H6F3NO