2-Hydroxy-4-(trifluoromethyl)quinoline

Product Name: 2-Hydroxy-4-(trifluoromethyl)quinoline
CAS No.: 25199-84-2
Chemical Name: 2-Hydroxy-4-(trifluoromethyl)quinoline
Synonyms: BUTTPARK 33\04-80;4-(Trifluoromethyl)quinolin-2-ol;4-Trifluoromethyl-1H-quinolin-2-one;4-trifluoroMethyl-2(1H)-quinolinone;4-(trifluoromethyl)quinolin-2(1H)-one;2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE;4--(TrifluoroMethyl)quinoline-2(H)-one;2-hydroxy-4-(trifluoroMethyl)quinqline;4-Trifluoromethyl-2(1H)-quinolinone,97%;2(1H)-Quinolinone, 4-(trifluoromethyl)-
CBNumber: CB0496696
Molecular Formula: C10H6F3NO
Formula Weight: 213.16
MOL File: 25199-84-2.mol

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2-Hydroxy-4-(trifluoromethyl)quinoline Property

Melting point:: >240°C
Boiling point:: 284 ºC
Density: 1.391
Flash point:: 126 ºC
storage temp.: Sealed in dry,Room Temperature
form: Solid
color: White
InChI: InChI=1S/C10H6F3NO/c11-10(12,13)7-5-9(15)14-8-4-2-1-3-6(7)8/h1-5H,(H,14,15)
InChIKey: UUROBWTVZZNDFD-UHFFFAOYSA-N
SMILES: N1C2=C(C=CC=C2)C(C(F)(F)F)=CC1=O
CAS DataBase Reference: 25199-84-2

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Safety

Safety Statements: 24/25
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: H61732
Product name: 4-Trifluoromethyl-2(1H)-quinolinone, 97%
Packaging: 1g
Price: $264
Updated: 2024/03/01

Alfa Aesar

Product number: H61732
Product name: 4-Trifluoromethyl-2(1H)-quinolinone, 97%
Packaging: 250mg
Price: $92.2
Updated: 2023/06/20

TRC

Product number: T900055
Product name: 4-(trifluoromethyl)quinolin-2(1H)-one
Packaging: 50mg
Price: $90
Updated: 2021/12/16

Matrix Scientific

Product number: 074152
Product name: 2-Hydroxy-4-(trifluoromethyl)quinoline
Purity: 95+%
Packaging: 1g
Price: $416
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 37718
Product name: 2-Hydroxy-4-(trifluoromethyl)quinoline
Purity: 95+%
Packaging: 1g
Price: $447
Updated: 2021/12/16

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2-Hydroxy-4-(trifluoromethyl)quinoline Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

4-Trifluoromethylquinolin-2(1H)-one was prepared by reacting aniline and ethyl-4,4,4-trifluoroacetoacetate stirred in toluene.
Experimental Procedure: In a 1 L round flask fitted with a reflux condenser a mixture of 25.60 g aniline, 50.0 g ethyl-4,4,4-trifluoroacetoacetate 300 ml toluene was heated to reflux in an oil bath at 130 °C. After 20 min 3 ml water was added and the mixture was heated at reflux for another 24 h. the reaction mixture was cooled to room temperature and concentrated under reduced pressure. A round flask with 200 mL H2SO4 was heated to 80°C and the crude oil from the step before was added in portions to the H2SO4 keeping the internal temperature below 90°C, total addition time was approximately 40 min. After addition was complete, the mixture was stirred at 80°C for 1 h, cooled and poured onto 400 g crushed ice. The resulting solids were filtered, washed with water, and dried under vacuum at 40°C to give 33.0 g (50%) product (2-Hydroxy-4-(trifluoromethyl)quinoline) as a colorless solid.

2-Hydroxy-4-(trifluoromethyl)quinoline Preparation Products And Raw materials

Raw materials

Ethyl 4,4,4-trifluoroacetoacetate 4-Fluoroaniline Sulfuric acid

Preparation Products

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2-Hydroxy-4-(trifluoromethyl)quinoline Suppliers

China 95 France 1 India 2 United Kingdom 7 United States 12 Global 117

Suzhouhongxiong

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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View Lastest Price from 2-Hydroxy-4-(trifluoromethyl)quinoline manufacturers

Career Henan Chemical Co

Product: 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE 25199-84-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200KG
Release date: 2018-12-23

25199-84-2, 2-Hydroxy-4-(trifluoromethyl)quinolineRelated Search:

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BUTTPARK 33\04-80

2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE

4-(Trifluoromethyl)quinolin-2-ol

4-Trifluoromethyl-1H-quinolin-2-one

2-Hydroxy-4-(trifluoromethyl)quinoline ,98%

4-(trifluoromethyl)quinolin-2(1H)-one

2-hydroxy-4-(trifluoroMethyl)quinqline

4--(TrifluoroMethyl)quinoline-2(H)-one

4-trifluoroMethyl-2(1H)-quinolinone

2(1H)-Quinolinone, 4-(trifluoromethyl)-

4-Trifluoromethyl-2(1H)-quinolinone,97%

2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE ISO 9001：2015 REACH

25199-84-2

C10H6F3NO