1,2,3,4-Tetrahydro-8-hydroxyquinoline
- Product Name
- 1,2,3,4-Tetrahydro-8-hydroxyquinoline
- CAS No.
- 6640-50-2
- Chemical Name
- 1,2,3,4-Tetrahydro-8-hydroxyquinoline
- Synonyms
- AKOS BB-8745;Ferroptosis-IN-21;AKOS BBS-00001526;1,2,3,4-TETRAHYDROQUINOLIN-8-OL;1,2,3,4-TETRAHYDRO-8-QUINOLINOL;8-Quinolinol, 1,2,3,4-tetrahydro-;1,2,3,4-TETRAHYDRO-8-HYDROXYQUINOLINE;8-hydroxy-1,2,3,4-Tetrahydro-quinolin;8-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE;1,2,3,4-Tetrahydro-8-hydroxyquinoline ISO 9001：2015 REACH
- CBNumber
- CB7345184
- Molecular Formula
- C9H11NO
- Formula Weight
- 149.19
- MOL File
- 6640-50-2.mol
1,2,3,4-Tetrahydro-8-hydroxyquinoline Property
- Melting point:
- 121-121.5 °C
- Boiling point:
- 300.9±31.0 °C(Predicted)
- Density
- 1.141±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- solid
- pka
- 11.17±0.20(Predicted)
- color
- Light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H320Causes eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- H999818
- Product name
- 8-Hydroxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W7741
- Product name
- 8-Hydroxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 1g
- Price
- $97
- Updated
- 2021/12/16
- Product number
- 010705
- Product name
- 1,2,3,4-Tetrahydro-quinolin-8-ol
- Packaging
- 500mg
- Price
- $30
- Updated
- 2021/12/16
- Product number
- P000055954
- Product name
- 1,2,3,4-Tetrahydro-8-hydroxyquinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $38
- Updated
- 2021/12/16
- Product number
- 010705
- Product name
- 1,2,3,4-Tetrahydro-quinolin-8-ol
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
1,2,3,4-Tetrahydro-8-hydroxyquinoline Chemical Properties,Usage,Production
Chemical Properties
Pink crystals
Synthesis
148-24-3
6640-50-2
The general procedure for the synthesis of 8-hydroxy-1,2,3,4-tetrahydroquinoline from 8-hydroxyquinoline was as follows: 100 mmol of 8-hydroxyquinoline and polymer microspheres Poly (DVB-co-NVP) loaded with 0.7 mmol of rhodium catalyst were added to 500 ml of water and the mixture was transferred to a reactor. The air in the reaction kettle was replaced five times with hydrogen and then filled with hydrogen to atmospheric pressure. The reaction was stirred at room temperature (25°C) and atmospheric pressure (1 atm) for 40 minutes. Upon completion of the reaction, aqueous phase extraction was performed three times, each time using ether as the extraction solvent. All ether extracts were combined and the ether was removed by rotary evaporator to give dry 8-hydroxy-1,2,3,4-tetrahydroquinoline in 95% yield.
References
[1] Chemical Communications, 2013, vol. 49, # 63, p. 7052 - 7054
[2] Patent: CN105884684, 2016, A. Location in patent: Paragraph 0018; 0019
[3] Journal of Organic Chemistry, 2008, vol. 73, # 21, p. 8639 - 8642
[4] Tetrahedron, 2009, vol. 65, # 47, p. 9737 - 9741
[5] Journal of Organometallic Chemistry, 2016, vol. 821, p. 197 - 205
1,2,3,4-Tetrahydro-8-hydroxyquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,2,3,4-Tetrahydro-8-hydroxyquinoline manufacturers
- Product
- 1,2,3,4-Tetrahydro-8-hydroxyquinoline 6640-50-2
- Price
- US $1190.00/g
- Min. Order
- 1g
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-02-19