ChemicalBook > CAS DataBase List > BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE

Product Name: BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE
CAS No.: 121505-93-9
Chemical Name: BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE
Synonyms: Boc-Gly-N(OMe);BOC-GLY-N(OME)ME;BOC-GLY-NME(OME);(Tert-Butoxy)Carbonyl Gly-N(OMe)Me;BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE;N-Boc-glycine N'-methoxy-N'-methylamide;2-(Boc-amino)-N-methoxy-N-methylacetamide;N-alpha-Boc-glycine-N-methyl-N-methoxy amide;BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE USP/EP/BP;Boc-glycineN,O-dimethylhydroxamide≥ 99% (HPLC)
CBNumber: CB2391904
Molecular Formula: C9H18N2O4
Formula Weight: 218.25
MOL File: 121505-93-9.mol

Less

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE Property

Melting point:: 100-104 °C(lit.)
Density: 1.090±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 11.03±0.46(Predicted)
color: White to Off-White
InChI: InChI=1S/C9H18N2O4/c1-9(2,3)15-8(13)10-6-7(12)11(4)14-5/h6H2,1-5H3,(H,10,13)
InChIKey: XJVZHKXGDQXSNT-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NCC(N(OC)C)=O

Less

Safety

WGK Germany: 3
HS Code: 2924190090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 465127
Product name: N-(tert-Butoxycarbonyl)glycine N′-methoxy-N′-methylamide
Purity: 98%
Packaging: 5g
Price: $178
Updated: 2025/07/31

TRC

Product number: B692970
Product name: tert-Butyl(2-(Methoxy(methyl)amino)-2-oxoethyl)carbamate
Packaging: 10g
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB35864
Product name: N-(tert-Butoxycarbonyl)glycine N'-methoxy-N'-methylamide
Packaging: 5G
Price: $90
Updated: 2021/12/16

ChemPep

Product number: 110803
Product name: Boc-Gly-N(OMe)Me
Purity: ≥98%
Packaging: 5g
Price: $100
Updated: 2021/12/16

Chem-Impex

Product number: 05079
Product name: Boc-glycineN,O-dimethylhydroxamide,99%(HPLC)
Purity: 99%(HPLC)
Packaging: 25G
Price: $106.4
Updated: 2021/12/16

Less

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

α-Amino Weinreb amide.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

4530-20-5

1117-97-1

121505-93-9

To a stirred solution of (tert-butoxycarbonyl)glycine (5.0 g, 28.57 mmol) and triethylamine (4.1 mL, 31.42 mmol) in dichloromethane (80 mL) was added N,O-dimethylhydroxylamine hydrochloride (3.0 g, 31.42 mmol). Subsequently, the reaction mixture was stirred at room temperature for 12 hours by dropwise addition of a solution of N,N'-dicyclohexylcarbodiimide (6.5 g, 31.42 mmol) in dichloromethane (20 mL). The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth and washed with dichloromethane. The filtrate was concentrated under reduced pressure to give the crude product, which was purified by silica gel column chromatography using 10% ethyl acetate/hexane as eluent to give the final N-BOC-glycine-N'-methoxy-N'-methylamide (6.0 g, 97.0%) as an off-white solid.1H NMR (400 MHz, CDCl3): δ 5.27 (broad single peak, 1H), δ 4.08 (broad single peak, 2H), 3.72 (single peak, 3H), 3.21 (single peak, 3H), 1.46 (single peak, 9H).

References

[1] Patent: WO2018/165520, 2018, A1. Location in patent: Page/Page column 226-227
[2] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 12, p. 2180 - 2183
[3] Journal of Organic Chemistry, 2006, vol. 71, # 17, p. 6678 - 6681
[4] Nucleosides, Nucleotides and Nucleic Acids, 2001, vol. 20, # 4-7, p. 1393 - 1397
[5] Arzneimittel-Forschung/Drug Research, 1989, vol. 39, # 4, p. 432 - 437

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE Suppliers

China 133 Germany 1 India 1 Switzerland 1 United Kingdom 2 United States 16 Global 154

Sci General Material & Chemical Ltd

Tel: 021-58388037;21-58388037 13472507714
Email: 35177634@qq.com;1589045147@qq.com
Country: China
ProdList: 803
Advantage: 55

Chengdu Forest Science and Technology Development Co., Ltd.

Tel: 18030648795
Fax: 028-61777050
Email: sales@cdforestchem.com
Country: China
ProdList: 2000
Advantage: 58

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Sichuan Ampebiochem Co., Ltd.

Tel: 028-65294243 13981822079;18682730901
Email: sales@ampebiochem.com
Country: China
ProdList: 1000
Advantage: 58

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai Mayzem Pharmtech Co., Ltd.

Tel: 18501708306; 18501708306
Fax: 021-68362870
Email: sales@mayzem.com
Country: China
ProdList: 518
Advantage: 56

Shanghai YuanQi Biotechnology Co., Ltd.

Tel: +86-2332782371 +86-18120098618
Email: sales@adobechem.com
Country: China
ProdList: 1250
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Shanghai Carlow Chemicals Co., Ltd.

Tel: 21-33526724 18930996265
Fax: +86 21 37023730
Email: info@carlowchem.com
Country: China
ProdList: 1969
Advantage: 50

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1853
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8258
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29759
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Adobe Chem Co., Ltd.

Tel: 2332782371
Fax: QQ: 2332782371
Email: adobechem@qq.com
Country: China
ProdList: 7980
Advantage: 58

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9976
Advantage: 55

Sichuan jiayinglai technology CO.,LTD

Tel: 028-028-88457210 18190964009
Fax: QQ3213375147
Email: 3054240163@qq.com
Country: China
ProdList: 2293
Advantage: 55

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Runnuo Biotechnology Co., Ltd.

Tel: 010-80768286
Country: CHINA
ProdList: 90
Advantage: 58

Kanghua (Shanghai) New Drug Development Co., Ltd.

Tel: 021-61263370 18901917034
Email: xingli@glbiochem.com
Country: China
ProdList: 5637
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Shanghai Jifeng Biotechnology Co., Ltd.

Tel: 021-61263377 15023907684
Fax: 021-61263399
Email: 15800684150@163.com
Country: China
ProdList: 8131
Advantage: 58

Finetech Industry Limited

Tel: +86-27-8746-5837 +8619945049750
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9629
Advantage: 58

Less

View Lastest Price from BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE manufacturers

Career Henan Chemical Co

Product: BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE 121505-93-9
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-09

121505-93-9, BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDERelated Search:

BOC-Glycine BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE BOC-TRP-N(OCH3)CH3 BOC-PHE-N(OCH3)CH3 BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE 1-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE BOC-ILE-N(OCH3)CH3 BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE N-BOC-S-TRITYLCYSTEIN-N-METHOXY-N-METHYLAMIDE BOC-ALA-N(OCH3)CH3 BOC-O-BENZYL-L-SERINE N,O-DIMETHYLHYDROXAMIDE N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE CIVENTICHEM CV-4039 tert-butyl 3-[methoxy(methyl)carbamoyl]morpholine-4-carboxylate tert-butyl 3-(S)-[methoxy(methyl)carbamoyl]morpholine-4-carboxylate 1-BOC-2-(METHOXY-METHYL-CARBAMOYL)AZEPANE 3-TERT-BUTOXYCARBONYLAMINO-N-METHOXY-N-METHYL-SUCCINAMIC ACID BENZYL ESTER

N-alpha-Boc-glycine-N-methyl-N-methoxy amide

Carbamic acid, N-[2-(methoxymethylamino)-2-oxoethyl]-, 1,1-dimethylethyl ester

2-(Boc-amino)-N-methoxy-N-methylacetamide

Boc-Gly-N(OMe)

Boc-glycineN,O-dimethylhydroxamide≥ 99% (HPLC)

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE

BOC-GLY-NME(OME)

BOC-GLY-N(OME)ME

N-(TERT-BUTOXYCARBONYL)GLYCINE N'-METHOXY-N'-METHYLAMIDE

N-(tert-butoxycarbonyl)glycine N'-methoxy-N'-meth

tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate

N-[2-[methoxy(methyl)amino]-2-oxoethyl]carbamic acid tert-butyl ester

2-Amino-N-methoxy-N-methylacetamide, 2-BOC protected

tert-Butyl {2-[methoxy(methyl)amino]-2-oxoethyl}carbamate, N-(tert-Butoxycarbonyl)glycine N'-methoxy-N'-methylamide

[(N-Methoxy-N-methylcarbamoyl)methyl]carbamic acid tert-butyl ester

N-(tert-Butoxycarbonyl)glycine Nμ-Methoxy-Nμ-MethylaMide

N-(tert-Butoxycarbonyl)glycine N'-Methoxy-N'-MethylaMide 98%

(Tert-Butoxy)Carbonyl Gly-N(OMe)Me

ert-butylN-[2-[methoxy(methyl)amino]-2-oxoethyl]carbamate

BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE USP/EP/BP

tert-butyl N-[2-[methoxy(methyl)amino]-2-oxoethyl]carbamate

N-Boc-glycine N'-methoxy-N'-methylamide

N-(tert-Butoxycarbonyl)glycine N′-methoxy-N′-methylamide

N-(tert-Butoxycarbonyl)glycine N′-methoxy-N′-methylamide, CAS 121505-93-9

121505-93-9

CH33COCONHCH2CONOCH3CH3

Amino Acid Derivatives

Peptide Synthesis

Specialty Synthesis

Amino Acid Derivatives

Amino Acids

Glycine

Peptide Synthesis