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Aminoacetaldehyde dimethyl acetal

Product Name
Aminoacetaldehyde dimethyl acetal
CAS No.
22483-09-6
Chemical Name
Aminoacetaldehyde dimethyl acetal
Synonyms
AMINOACETALDEHYDE DIMETHYL ACETAL;2,2-Dimethoxyethanamine;AMINOACETOLDEHYDE DIMETHYL ACETOL;2,2-Dimethyethanamine;Aminoacetaldehyde dimethyl acetal ,98%;AMINOACETALDEHYDE DIMETHYL ACETAL (OR) 2,2- DIMETHOXYETHYLAMINE (ADMA);anjiahuanchun;DIMETHYLAMINOACETAL;Dimethoxyethylamine;Aminoacetaldehyde di
CBNumber
CB2394455
Molecular Formula
C4H11NO2
Formula Weight
105.14
MOL File
22483-09-6.mol
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Aminoacetaldehyde dimethyl acetal Property

Melting point:
-78°C
Boiling point:
135-139 °C/95 mmHg (lit.)
Density 
0.965 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.417(lit.)
Flash point:
128 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
soluble in Chloroform, Methanol
pka
6.95±0.10(Predicted)
form 
Liquid
color 
Clear colorless to pale yellow
Water Solubility 
miscible
BRN 
741868
InChIKey
QKWWDTYDYOFRJL-UHFFFAOYSA-N
CAS DataBase Reference
22483-09-6(CAS DataBase Reference)
NIST Chemistry Reference
Aminoacetaldehyde dimethyl acetal(22483-09-6)
EPA Substance Registry System
Ethanamine, 2,2-dimethoxy- (22483-09-6)
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Safety

Hazard Codes 
C,F,Xi
Risk Statements 
10-34-36/37/38
Safety Statements 
26-36/37/39-45-16-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
2
Hazard Note 
Flammable/Corrosive
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29225000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
121967
Product name
Aminoacetaldehyde dimethyl acetal
Purity
99%
Packaging
25ml
Price
$64.5
Updated
2024/03/01
Sigma-Aldrich
Product number
121967
Product name
Aminoacetaldehyde dimethyl acetal
Purity
99%
Packaging
100ml
Price
$171
Updated
2024/03/01
TCI Chemical
Product number
A0801
Product name
Aminoacetaldehyde Dimethyl Acetal
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
A0801
Product name
Aminoacetaldehyde Dimethyl Acetal
Purity
>98.0%(GC)(T)
Packaging
250mL
Price
$289
Updated
2024/03/01
Alfa Aesar
Product number
A15498
Product name
Aminoacetaldehyde dimethyl acetal, 99%
Packaging
25g
Price
$47.65
Updated
2024/03/01
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Aminoacetaldehyde dimethyl acetal Chemical Properties,Usage,Production

Description

Aminoacetaldehyde dimethyl acetal, also known as 2,2-dimethoxy-ethylamine, is a critical intermediate in the synthesis of ivabradine hydrochloride, proline analogs, praziquantel, and other raw materials. The existing process for producing aminoacetal dimethyl acetate uses vinyl acetate as the starting material, and the target product is synthesized through bromination, Gabriel synthesis, and hydrazinolysis.

Chemical Properties

clear colorless to pale yellow liquid

Uses

Amino acetaldehyde dimethyl was used in preparation of chitosan- dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO4 leading to α-aminophosphonates.

General Description

Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine.

Purification Methods

Dry the acetal over KOH pellets and distil it through a 30cm vacuum jacketed Vigreux column (p 11). [Lawson J Am Chem Soc 75 3398 1953, Erickson et al. J Am Chem Soc 77 6640 1955, Beilstein 4 IV 1918.]

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Aminoacetaldehyde dimethyl acetal Suppliers

Henan Chongyi Biopharmaceutical Co., Ltd
Tel
182-57818007 13566934155
Fax
QQ1571202295
Email
1571202295@qq.com
Country
China
ProdList
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58
Huzhou Chenxi Environmental Protection Technology Co., Ltd.
Tel
0572-0572-16762203950 16762203950
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3775386035@qq.com
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China
ProdList
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58
Shanghai zhiping biology science and technology co., ltd
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13621780388
Email
494972302@qq.com
Country
China
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58
Hangzhou Xingui Industrial Co., Ltd.
Tel
0571-86692169 15397065278
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476137679@qq.com
Country
China
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58
XIANJU DOEASTCHEM Co., Ltd.
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0576-87788985 13586230158
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504833149@qq.com
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China
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Fuxin Kaituo Fine Chemical Technology Co., Ltd
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15714082442
Email
15714082442@163.com
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China
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Hubei huizepu Pharmaceutical Technology Co., Ltd
Tel
027-19371-3712 19371278702
Fax
QQ:2462856504
Email
n17762444226@163.com
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China
ProdList
3002
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Jinan Dexinjia Bio&Tech Co., Ltd
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0531-82375886 13001715031
Fax
0531-82375893
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3517280075@qq.com
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China
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Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
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tongtf110@sina.com
Country
China
ProdList
972
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
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View Lastest Price from Aminoacetaldehyde dimethyl acetal manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Aminoacetaldehyde dimethyl acetal 22483-09-6
Price
US $70.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-05
Asia Chem I and E (Jiangsu) Co Ltd
Product
Aminoacetaldehyde dimethyl acetal 22483-09-6
Price
US $39.10/Kg/Drum
Min. Order
200Kg/Drum
Purity
99.00%HPLC
Supply Ability
10tons/month
Release date
2021-11-09
Jinan Finer Chemical Co., Ltd
Product
2,2-Dimethoxyethylamine 22483-09-6
Price
US $0.00/KG
Min. Order
1KG
Purity
≥99%
Supply Ability
1000mt/year
Release date
2023-05-18

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