ChemicalBook > CAS DataBase List > 4-HYDROXYANTIPYRINE

4-HYDROXYANTIPYRINE

Product Name
4-HYDROXYANTIPYRINE
CAS No.
1672-63-5
Chemical Name
4-HYDROXYANTIPYRINE
Synonyms
NSC 174055;4-HYDROXYANTIPYRINE;Antipyrine Impurity 5;4-Hydroxyantipyrine, 10 mM in DMSO;4-hydroxy-1,5-dimethyl-2-phenylpyrazol-3-one;4-hydroxy-1,5-dimethyl-2-phenyl-pyrazol-3-one;4-HYDROXY-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE;1,5-Dimethyl-2-phenyl-4-hydroxy-4-pyrazoline-3-one;4-Hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one;2,3-Dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3-one
CBNumber
CB2415846
Molecular Formula
C11H12N2O2
Formula Weight
204.23
MOL File
1672-63-5.mol
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4-HYDROXYANTIPYRINE Property

Melting point:
184-186 °C (lit.)
Boiling point:
314.3±52.0 °C(Predicted)
Density 
1.294±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
11.99±0.20(Predicted)
color 
Off-White to Beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
109428
Product name
4-Hydroxyantipyrine
Purity
99%
Packaging
5g
Price
$153
Updated
2025/07/31
Sigma-Aldrich
Product number
76561
Product name
4-Hydroxyantipyrine
Purity
analytical standard
Packaging
100mg
Price
$99
Updated
2022/05/15
TRC
Product number
H801805
Product name
4-Hydroxyantipyrine
Packaging
100mg
Price
$215
Updated
2021/12/16
AK Scientific
Product number
1404AQ
Product name
4-Hydroxyantipyrine
Packaging
5g
Price
$176
Updated
2021/12/16
ChemScene
Product number
CS-0020302
Product name
4-Hydroxyantipyrine
Purity
98.59%
Packaging
250mg
Price
$700
Updated
2021/12/16
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4-HYDROXYANTIPYRINE Chemical Properties,Usage,Production

Uses

Antipyrine metabolite

Uses

4-Hydroxyantipyrine is a metabolite of antipyrine (A697500) which is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

Uses

4-Hydroxyantipyrine was used to study the relationships between the metabolism of antipyrine, hexobarbitone and theophylline in man. It was used in a study on flow injection analysis system for the characterisation of pharmaceutical compounds via combination of diode array UV, 1H NMR, FT-IR spectroscopy and time-of-flight mass spectrometry.

Definition

ChEBI: 4-hydroxy-1,5-dimethyl-2-phenyl-3-pyrazolone is a ring assembly and a member of pyrazoles.

General Description

4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine. It is a metabolite of antipyrine.

4-HYDROXYANTIPYRINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXYANTIPYRINE Suppliers

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1672-63-5, 4-HYDROXYANTIPYRINERelated Search:

Acethydrazide 1，2-Dimethyl hydrazine CROTONAMIDE N-methyl-N-formylhydrazine 1,3-Dimethyl-5-hydroxypyrazole N-METHYLACRYLAMIDE 2-Hydroxyethylhydrazine ETHYLHYDRAZINE FORMANILIDE TETRAMETHYLHYDRAZINE 3H-PYRAZOL-3-ONE, 1,2-DIHYDRO- Allylamine Phenylhydrazine N-PHENYLACRYLAMIDE 4-HYDROXYANTIPYRINE Acrylamide 2-HYDROXYACETAMIDE Crotylamine

  • 4-HYDROXYANTIPYRINE
  • 4-HYDROXY-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE
  • 1,5-Dimethyl-2-phenyl-4-hydroxy-4-pyrazoline-3-one
  • 2,3-Dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3-one
  • 4-hydroxy-1,5-dimethyl-2-phenyl-pyrazol-3-one
  • 4-hydroxy-1,5-dimethyl-2-phenylpyrazol-3-one
  • NSC 174055
  • 4-Hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
  • 3H-Pyrazol-3-one, 1,2-dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-
  • Antipyrine Impurity 5
  • 4-hydroxy AntipyrineQ: What is 4-hydroxy Antipyrine Q: What is the CAS Number of 4-hydroxy Antipyrine Q: What is the storage condition of 4-hydroxy Antipyrine Q: What are the applications of 4-hydroxy Antipyrine
  • Citicoline,inhibit,concentration ratio,4-Hydroxyantipyrine,NSC174055,4 Hydroxyantipyrine,BBB,NSC-174055,NSC 174055,Distribution,Antipyrine,4Hydroxyantipyrine,brain,Inhibitor,4-Hydroxyphenazone
  • 4-Hydroxyantipyrine, 10 mM in DMSO
  • 1672-63-5
  • Pyrazoles
  • Heterocyclic Compounds