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Malonamide

Product Name
Malonamide
CAS No.
108-13-4
Chemical Name
Malonamide
Synonyms
PROPANEDIAMIDE;MALONDIAMIDE;NSC 2134;MALONAMIDE;MALONODIAMIDE;Malonamide>AURORA KA-4099;malonicdiamide;Malonyldiamide;Malonamide 98%
CBNumber
CB2418973
Molecular Formula
C3H6N2O2
Formula Weight
102.09
MOL File
108-13-4.mol
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Malonamide Property

Melting point:
172-175 °C (lit.)
Boiling point:
191.38°C (rough estimate)
Density 
1.3516 (rough estimate)
refractive index 
1.5110 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in HCl.
pka
7.00±0.70(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
180 g/L (20 ºC)
BRN 
1751401
InChI
InChI=1S/C3H6N2O2/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7)
InChIKey
WRIRWRKPLXCTFD-UHFFFAOYSA-N
SMILES
C(N)(=O)CC(N)=O
CAS DataBase Reference
108-13-4(CAS DataBase Reference)
NIST Chemistry Reference
Propanediamide(108-13-4)
EPA Substance Registry System
Propanediamide (108-13-4)
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Safety

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
ON9125000
TSCA 
Yes
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129593
Product name
Malonamide
Purity
97%
Packaging
100g
Price
$56.58
Updated
2024/03/01
TCI Chemical
Product number
M0027
Product name
Malonamide
Purity
>98.0%(N)
Packaging
25g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
M0027
Product name
Malonamide
Purity
>98.0%(N)
Packaging
500g
Price
$199
Updated
2024/03/01
Alfa Aesar
Product number
A17939
Product name
Malonamide, 98%
Packaging
100g
Price
$65.65
Updated
2024/03/01
Alfa Aesar
Product number
A17939
Product name
Malonamide, 98%
Packaging
500g
Price
$204.65
Updated
2024/03/01
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Malonamide Chemical Properties,Usage,Production

Description

Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.

Chemical Properties

White crystalline powder

Uses

Malonamide is a reagent for fluorimetric determination of reducing carbohydrates. The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare earth elements from nitric acid medium.

Uses

The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare-earth ions from nitric acid medium.

Uses

Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.

Definition

ChEBI: Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.

General Description

The malonamide derivatives are obtained by the one-pot, five-component condensation reaction of isocyanide, Meldrum′s acid, arylidene malononitrile, and two amine molecules in CH2Cl2.

Hazard

Mildly toxic by ingestion.

Synthesis

The synthesis of Malonamide is as follows:
A typical reaction was carried out in a 10 mL flask. Benzonitrile (2 mmol), CuII-4 ? (0.2 g), acetaldoxime (6 mmol) and MeOH (4 mL) were stirred at 65 °C for 4 h. The solid was filtered, washed with MeOH and the filtrate evaporated. The residue was subjected to GC-MS analysis and NMR spectroscopy. The filtered catalyst can be recycled after drying at about 150 °C for 1 h.

Purification Methods

Crystallise the amide from water. [Beilstein 2 IV 1887.]

Malonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Malonamide Suppliers

Aurora Fine Chemicals Ltd.
Tel
--
Fax
--
Email
aurora@aurorafinechemicals.com
Country
Austria
ProdList
6625
Advantage
72
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View Lastest Price from Malonamide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Malonamide 108-13-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-11
Hebei Chuanghai Biotechnology Co,.LTD
Product
Malonamide 108-13-4
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2024-08-23
Hebei Mojin Biotechnology Co., Ltd
Product
Malonamide 108-13-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-25

108-13-4, MalonamideRelated Search:


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  • Organic Building Blocks
  • Fluorescent Probes, Labels, Particles and Stains
  • Detection
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  • Biochemicals and Reagents
  • BioChemical
  • Amides
  • Carbonyl Compounds
  • Aliphatics
  • Miscellaneous Reagents
  • Amides
  • Biochemicals and Reagents
  • Building Blocks
  • C2 to C7
  • Carbonyl Compounds
  • Chemical Synthesis
  • Derivatization agents
  • Luminescent Compounds/Detection
  • Organic Building Blocks
  • Wavelength Index
  • API intermediates