ChemicalBook > CAS DataBase List > (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE

Product Name
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
CAS No.
22677-21-0
Chemical Name
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
Synonyms
RHPD;In1122 Impurity 78;Oxiracetam Impurity P;(R)-4-hydoroxyoyrolidone;4-hydroxy-R-2-pyrrolidine;(R)-4-HYDROXY-2-PYRROLIDONE;(r)-β-hydroxy-γ-butyrolactam;（R)+4-hydroxy-2-prrolidinone;(R)-4-hydroxy-2-pyrrolidione;(4R)-4-hydroxy-2-pyrrolidone
CBNumber
CB2438434
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
22677-21-0.mol
More
Less

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Property

Melting point:
156-160 °C
Boiling point:
363.6±35.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka
13.62±0.20(Predicted)
form 
Powder
color 
White to pale yellow
optical activity
[α]23/D +43°, c = 1 in ethanol
Water Solubility 
Slightly soluble in water.
BRN 
1524193
InChIKey
IOGISYQVOGVIEU-GSVOUGTGSA-N
CAS DataBase Reference
22677-21-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-38-37-36
Safety Statements 
26
WGK Germany 
3
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
479160
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
1g
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
479160
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
5g
Price
$417
Updated
2023/06/20
Alfa Aesar
Product number
H66006
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
250mg
Price
$42.7
Updated
2023/06/20
Alfa Aesar
Product number
H66006
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
1g
Price
$113
Updated
2021/12/16
TRC
Product number
H953070
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Packaging
1g
Price
$1110
Updated
2021/12/16
More
Less

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

The (R)-enantiomer intermediate in the preparation of Oxiracetam

Uses

(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Suppliers

Canada 1 China 133 France 1 Germany 4 India 8 Japan 2 South Korea 3 Switzerland 1 United Kingdom 7 United States 20 Global 180
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
More
Less

View Lastest Price from (R)-(+)-4-HYDROXY-2-PYRROLIDINONE manufacturers

Career Henan Chemical Co
Product
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE 22677-21-0
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

22677-21-0, (R)-(+)-4-HYDROXY-2-PYRROLIDINONERelated Search:

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE (3R,4R)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione (S)-(+)-4-HYDROXY-2-PYRROLIDINONE,(S)-4-HYDROXY-2-PYRROLIDINONE,(S)-(-)-4-HYDROXY-2-PYRROLIDINONE 4-Hydroxy-2-pyrrolidinone (S)-(-)-3-hydroxy-2-pyrrolidinone (S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE 3-HYDROXY-2-PYRROLIDINONE (S)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE ALPHA-PYRIDOIN (R)-(+)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE,(R)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE 3-CYCLOPENTYL-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (3R,4S)-1-BENZYL-3,4-DIHYDROXY-2,5-PYRROLIDINEDIONE 4-OXO-3-PHENETHYL-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (+)-TARTRANIL 3-(2-DIETHYLAMINO-ETHYL)-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID 3-(3-METHOXY-PROPYL)-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (S)-4-HYDROXY-2-PYRROLIDINONE-1-N-ACETIC ACID R(+)-3-AMINO-1-HYDROXY-2-PYRROLIDINONE

  • (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
  • (R)-4-HYDROXY-2-PYRROLIDINONE
  • (R)-4-HYDROXY-2-PYRROLIDONE
  • (R)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
  • RHPD
  • 2-PYRROLIDINONE, 4-HYDROXY-, (R)
  • 4-hydroxy-R-2-pyrrolidine
  • (r)-(+)-β-hydroxy-γ-butyrolactam
  • (r)-β-hydroxy-γ-butyrolactam
  • 2-Pyrrolidinone, 4-hydroxy-, (4R)-
  • (R)-4-hydoroxyoyrolidone
  • （R)+4-hydroxy-2-prrolidinone
  • (R)-4-Hydroxy-pyrrolidin-2-one
  • (4R)-4-Hydroxypyrrolidine-2-one
  • (R)-4β-Hydroxypyrrolidine-2-one
  • [4R,(-)]-4-Hydroxypyrrolidin-2-one
  • (R)-4-hydroxy-2-pyrrolidione
  • (4R)-4-hydroxy-2-pyrrolidone
  • (4R)-4-Hydroxy-2-pyrrolidinone
  • In1122 Impurity 78
  • Oxiracetam Impurity P
  • (R)-(+)-4-Hydroxy-2-pyrrolidinone, 97%,
  • 22677-21-0
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Pyrrole&Pyrrolidine&Pyrroline
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Drug Intermediates