ChemicalBook > CAS DataBase List > (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE

Product Name
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
CAS No.
22677-21-0
Chemical Name
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
Synonyms
RHPD;In1122 Impurity 78;Oxiracetam Impurity P;(R)-4-hydoroxyoyrolidone;4-hydroxy-R-2-pyrrolidine;(R)-4-HYDROXY-2-PYRROLIDONE;(r)-β-hydroxy-γ-butyrolactam;（R)+4-hydroxy-2-prrolidinone;(R)-4-hydroxy-2-pyrrolidione;(4R)-4-hydroxy-2-pyrrolidone
CBNumber
CB2438434
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
22677-21-0.mol
More
Less

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Property

Melting point:
156-160 °C
Boiling point:
363.6±35.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka
13.62±0.20(Predicted)
form 
Powder
color 
White to pale yellow
optical activity
[α]23/D +43°, c = 1 in ethanol
Water Solubility 
Slightly soluble in water.
BRN 
1524193
InChIKey
IOGISYQVOGVIEU-GSVOUGTGSA-N
CAS DataBase Reference
22677-21-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-38-37-36
Safety Statements 
26
WGK Germany 
3
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
479160
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
1g
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
479160
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Purity
97%
Packaging
5g
Price
$417
Updated
2023/06/20
Alfa Aesar
Product number
H66006
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
250mg
Price
$42.7
Updated
2023/06/20
Alfa Aesar
Product number
H66006
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%
Packaging
1g
Price
$113
Updated
2021/12/16
TRC
Product number
H953070
Product name
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Packaging
1g
Price
$1110
Updated
2021/12/16
More
Less

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

The (R)-enantiomer intermediate in the preparation of Oxiracetam

Uses

(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Suppliers

Canada 1 China 133 France 1 Germany 4 India 8 Japan 2 South Korea 3 Switzerland 1 United Kingdom 7 United States 20 Global 180
Shijiazhuang Lickon PharmaTech Co., Ltd.
Tel
031185291771 13832391721
Fax
0311-67305698
Email
yaofeng2005@163.com
Country
China
ProdList
975
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2963
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4000
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9459
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Sheepchem Co., Ltd.
Tel
+86 (21) 6715-7650
Fax
+86 (21) 6715-7651
Email
sheepchem@163.com
Country
China
ProdList
994
Advantage
60
Doly Chemical CO.,LTD.
Tel
021-34716221 15800796336
Fax
+86-21-31329566
Email
sales@dolypharm.com
Country
China
ProdList
292
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Chimica Laboratories Co., Ltd
Tel
0086-573-82585213
Fax
0086-573-82585233
Email
bai@chimicalabs.com
Country
China
ProdList
861
Advantage
64
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Jiaxing Novartis Chemical Co., Ltd.
Tel
18957373295
Fax
-
Country
China
ProdList
1580
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Tombiopharma Chemical Co. Ltd.
Tel
13391076197
Email
tombiopharma@163.com
Country
China
ProdList
4987
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Shanghai Mayzem Pharmtech Co., Ltd.
Tel
18501708306
Fax
021-68362870
Email
sales@mayzem.com
Country
China
ProdList
520
Advantage
56
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Jiangsu Mingchem Corporation
Tel
0519-85170101
Fax
0519-85170505
Email
sales@mingchem.com
Country
China
ProdList
606
Advantage
55
Struchem Co., Ltd.
Tel
0512-0512-63009836 15365350169
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3984
Advantage
60
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3795
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5902
Advantage
65
AgileBioChem Co., Ltd.
Tel
18055517827
Email
sales@agilebiochem.com
Country
China
ProdList
1008
Advantage
50
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shijiazhuang Yesheng Chemical Technology Co., Ltd
Tel
0311-68030586 18031147013
Fax
0311-68030586
Email
yeshengchemical@163.com
Country
China
ProdList
2686
Advantage
58
Changzhou Jiezhan Chemical Technology Co., Ltd
Tel
15861130028
Email
956912955@qq.com
Country
China
ProdList
288
Advantage
58
Shijiazhuang Moyi Chemical Technology Co., Ltd
Tel
0311-85511132 18031831025
Email
mingyu2011p@126.com
Country
China
ProdList
86
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
Nanijing m&m biotechnology Co. ,Ltd.
Tel
025-87782433 18021532344
Fax
025-87782433
Email
sales@marymebiotech.com
Country
China
ProdList
3980
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29791
Advantage
60
More
Less

View Lastest Price from (R)-(+)-4-HYDROXY-2-PYRROLIDINONE manufacturers

Career Henan Chemical Co
Product
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE 22677-21-0
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-24

22677-21-0, (R)-(+)-4-HYDROXY-2-PYRROLIDINONERelated Search:

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE (3R,4R)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione (S)-(+)-4-HYDROXY-2-PYRROLIDINONE,(S)-4-HYDROXY-2-PYRROLIDINONE,(S)-(-)-4-HYDROXY-2-PYRROLIDINONE 4-Hydroxy-2-pyrrolidinone (S)-(-)-3-hydroxy-2-pyrrolidinone (S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE 3-HYDROXY-2-PYRROLIDINONE (S)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE ALPHA-PYRIDOIN (R)-(+)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE,(R)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE 3-CYCLOPENTYL-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (3R,4S)-1-BENZYL-3,4-DIHYDROXY-2,5-PYRROLIDINEDIONE 4-OXO-3-PHENETHYL-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (+)-TARTRANIL 3-(2-DIETHYLAMINO-ETHYL)-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID 3-(3-METHOXY-PROPYL)-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (S)-4-HYDROXY-2-PYRROLIDINONE-1-N-ACETIC ACID R(+)-3-AMINO-1-HYDROXY-2-PYRROLIDINONE

  • (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
  • (R)-4-HYDROXY-2-PYRROLIDINONE
  • (R)-4-HYDROXY-2-PYRROLIDONE
  • (R)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
  • RHPD
  • 2-PYRROLIDINONE, 4-HYDROXY-, (R)
  • 4-hydroxy-R-2-pyrrolidine
  • (r)-(+)-β-hydroxy-γ-butyrolactam
  • (r)-β-hydroxy-γ-butyrolactam
  • 2-Pyrrolidinone, 4-hydroxy-, (4R)-
  • (R)-4-hydoroxyoyrolidone
  • （R)+4-hydroxy-2-prrolidinone
  • (R)-4-Hydroxy-pyrrolidin-2-one
  • (4R)-4-Hydroxypyrrolidine-2-one
  • (R)-4β-Hydroxypyrrolidine-2-one
  • [4R,(-)]-4-Hydroxypyrrolidin-2-one
  • (R)-4-hydroxy-2-pyrrolidione
  • (4R)-4-hydroxy-2-pyrrolidone
  • (4R)-4-Hydroxy-2-pyrrolidinone
  • In1122 Impurity 78
  • Oxiracetam Impurity P
  • (R)-(+)-4-Hydroxy-2-pyrrolidinone, 97%,
  • 22677-21-0
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Pyrrole&Pyrrolidine&Pyrroline
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Drug Intermediates