TRIMETHYLSILYL ISOTHIOCYANATE

Product Name: TRIMETHYLSILYL ISOTHIOCYANATE
CAS No.: 2290-65-5
Chemical Name: TRIMETHYLSILYL ISOTHIOCYANATE
Synonyms: ISOTHIOCYANATOTRIMETHYLSILANE;Trimethylsilyl Isothicyanate;TRIMETHYLSILYL ISOTHIOCYANATE;isothiocyanatotrimethyl-silan;Trimethylsilylisothiocyanate,94%;Silane, isothiocyanatotrimethyl-;Trimethylsilyl isothiocyanate,97%;(TriMethylsilyl)isothiocyanate 99%
CBNumber: CB2460765
Molecular Formula: C4H9NSSi
Formula Weight: 131.27
MOL File: 2290-65-5.mol

More

Less

TRIMETHYLSILYL ISOTHIOCYANATE Property

Melting point:: −32.8 °C(lit.)
Boiling point:: 143 °C(lit.)
Density: 0.931 g/mL at 25 °C(lit.)
vapor density: >1 (vs air)
refractive index: n20/D 1.482(lit.)
Flash point:: 95 °F
storage temp.: 2-8°C
form: liquid
Specific Gravity: 0.931
Water Solubility: Reacts with water.
Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
Sensitive: Moisture Sensitive
BRN: 1745262
InChIKey: XLTUPERVRFLGLJ-UHFFFAOYSA-N
CAS DataBase Reference: 2290-65-5(CAS DataBase Reference)
EPA Substance Registry System: Isothiocyanatotrimethylsilane (2290-65-5)

More

Less

Safety

Hazard Codes: T
Risk Statements: 10-23/24/25-36/37/38-42
Safety Statements: 23-26-36/37-45
RIDADR: UN 1992 3/PG 3
WGK Germany: 3
F: 10-19-21
TSCA: Yes
HazardClass: 3
PackingGroup: II
HS Code: 29319090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 230766
Product name: Trimethylsilyl isothiocyanate
Purity: 99%
Packaging: 50g
Price: $172.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 230766
Product name: Trimethylsilyl isothiocyanate
Purity: 99%
Packaging: 10g
Price: $257
Updated: 2024/03/01

Alfa Aesar

Product number: L03277
Product name: Trimethylsilyl isothiocyanate
Purity: 94%
Packaging: 5g
Price: $43.65
Updated: 2024/03/01

Alfa Aesar

Product number: L03277
Product name: Trimethylsilyl isothiocyanate
Purity: 94%
Packaging: 25g
Price: $194
Updated: 2024/03/01

Matrix Scientific

Product number: 153248
Product name: Trimethylsilyl isothiocyanate
Purity: 95%
Packaging: 10g
Price: $222
Updated: 2021/12/16

More

Less

TRIMETHYLSILYL ISOTHIOCYANATE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Trimethylsilyl isothiocyanate is used as derivatizing reagent during the synthesis of amino acid thiohydantoins. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

Uses

Trimethylsilyl isothiocyanate was used as derivatizing reagent during the synthesis of amino acid thiohydantoins.

General Description

Trimethylsilyl isothiocyanate (TMS-ITC) reacts with fullerene-mixed peroxide C₆₀(O)(OOtBu)₄ to yield isothiocyanate derivative C₆₀(NCS)(OH)(OOtBu)₄. TMS-ITC undergoes condensation with ethyl 2-benzylamino-5-methyl-3-phenylcyclopent-1-enecarboxylate to yield 1-benzyl-5-methyl-7-phenyl-2-thioxo-1,2,3,5,6,7-hexahydrocyclopentapyrimidin-4-one. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

Purification Methods

The 1H NMR spectrum should have only one peak; if not purify it by repeated fractionation in an all-glass system using a 50cm (4mm internal diameter) column without packing. [Anderson J Am Chem Soc 69 3049 1947, Fehér & Blümcke Chem Ber 90 1934 1957, Neidleim & Hege Synthesis 51 1975, Beilstein 4 III 1861, 4 IV 4011.]

TRIMETHYLSILYL ISOTHIOCYANATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

TRIMETHYLSILYL ISOTHIOCYANATE Suppliers

Belgium 1 China 38 Germany 2 India 1 Japan 1 Singapore 1 Switzerland 1 United Kingdom 5 United States 11 Global 61

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
ProdList: 5902
Advantage: 65

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Quzhou Rundong Chemical (Technology) Co.

Tel: 0570-8789886 18892685668
Fax: 0570-8789985
Email: info@rundongchemical.com
Country: China
ProdList: 3970
Advantage: 60

Shanghai Witofly Chemical Co. ,Ltd.

Tel: 021-5063062 15821189163
Email: sales@witofly.com
Country: China
ProdList: 1603
Advantage: 55

LinkChem Co.,Ltd.

Tel: 021-021-58950110 13124863828
Fax: 021-20922272
Email: sales@linkchem.cn
Country: China
ProdList: 2981
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd.

Tel: 0573-86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8025
Advantage: 58

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15494
Advantage: 58

Suzhou Siso new material Co.,Ltd.

Tel: 0512-65402974 18550909935;
Fax: 0512-67544899
Email: siso03@126.com
Country: China
ProdList: 1902
Advantage: 58

Shanghai Tube Pharmaceutical Co., Ltd.

Tel: 021-54338626 18017892860
Fax: 021-54338626
Email: sales@tubepharm.com
Country: China
ProdList: 2416
Advantage: 58

Chongqing Genco Pharmaceutical Co.,Ltd

Tel: 023-88654579 13637703915
Fax: 375097861
Email: 375097861@qq.com
Country: China
ProdList: 297
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

Shanghai Taijilin Industrial Co., Ltd.

Tel: 021-021-50630626 18964684208
Fax: 021-50563898
Email: kate@tajilin.com
Country: China
ProdList: 1231
Advantage: 58

Heze Lize Biotechnology Co., Ltd.

Tel: 10-15853052 15853052030
Email: ck@163.com15853052030
Country: China
ProdList: 298
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49374
Advantage: 58

Hubei xingongli Chemical Co., Ltd

Tel: 027-59106151 15172325309
Fax: 027-59503710
Email: 1400858877@qq.com
Country: China
ProdList: 9934
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 17691182729 18161915376
Email: 1046@dideu.com
Country: China
ProdList: 10001
Advantage: 58

Shandong Mingde Biotechnology Co., Ltd

Tel: 18560864701
Email: 1054234218@qq.com
Country: China
ProdList: 3581
Advantage: 58

Beijing Qinling Pharmaceutical Co., Ltd.

Tel: 010-61241352 18901327973
Email: 834537306@qq.com
Country: China
ProdList: 4680
Advantage: 58

Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd

Tel: 18072846723; 18072846723
Email: caigou1@witofly.com
Country: China
ProdList: 3071
Advantage: 58

Shanghai Yingxin laboratory equipment Co., Ltd

Tel: 021-021-59178156 15300768757
Email: 359382369@qq.com
Country: China
ProdList: 10674
Advantage: 58

Beijing FYF Chemicals Co., Ltd

Tel: 010-57903446 15869909019
Email: 168931144@qq.com
Country: China
ProdList: 4965
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48461
Advantage: 58

Shanghai Daken Advanced Materials Co.,Ltd

Tel: +86-371-66670886
Email: info@dakenam.com
Country: China
ProdList: 18751
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49978
Advantage: 58

Shaanxi Didu New Materials Co. Ltd

Tel: +86-89586680 +86-13289823923
Email: 1026@dideu.com
Country: China
ProdList: 8670
Advantage: 58

PT CHEM GROUP LIMITED

Tel: +86-85511178; +86-85511178;
Email: peter68@ptchemgroup.com
Country: China
ProdList: 35425
Advantage: 58

More

Less

View Lastest Price from TRIMETHYLSILYL ISOTHIOCYANATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: (Trimethylsilyl)isothiocyanate 99% 2290-65-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

2290-65-5, TRIMETHYLSILYL ISOTHIOCYANATERelated Search:

4-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER Ethyl isonicotinate Isothiazolinones Benzyl isocyanate Ethoxycarbonyl Isothiocyanate Benzyl thiocyanate Trimethoxy(pentamethylcyclopentadienyl) titanium(IV) 3-FLUOROPHENYL ISOCYANATE 4-Fluorophenyl isocyanate Ethyl isocyanoacetate Isopropyl isothiocyanate 2-ETHOXYPHENYL ISOCYANATE Isobutyl isocyanate TRIMETHYLSILYL ISOCYANATE triethyl(3-isocyanatopropyl)silane TRIMETHYLSILYL ISOTHIOCYANATE isothiocyanic acid

isothiocyanatotrimethyl-silan

Silane, isothiocyanatotrimethyl-

TRIMETHYLSILYL ISOTHIOCYANATE

ISOTHIOCYANATOTRIMETHYLSILANE

Trimethylsilylisothiocyanate,94%

Trimethylsilyl isothiocyanate,97%

(TriMethylsilyl)isothiocyanate 99%

Trimethylsilyl Isothicyanate

2290-65-5

C4H9NSSi

CH33SiNCS

Building Blocks

Sulfur Compounds

Thiocyanates/Isothiocyanates

Organic Building Blocks