ChemicalBook > CAS DataBase List > PHENOL, 5-BROMO-2-NITRO-

PHENOL, 5-BROMO-2-NITRO-

Product Name
PHENOL, 5-BROMO-2-NITRO-
CAS No.
27684-84-0
Chemical Name
PHENOL, 5-BROMO-2-NITRO-
Synonyms
5-bromo-2-ntrophenol;5-Bromo-2-nitrophenol;3-Bromo-6-nitrophenol;2-Nitro-5-bromophenol;PHENOL, 5-BROMO-2-NITRO-;5-Bromo-2-nitrophenol 98%;5-Bromo-2-nitrophenol, 96%,;5-BroMo-2-nitrophenol, 97+%;4-Bromo-2-hydroxynitrobenzene
CBNumber
CB2464293
Molecular Formula
C6H4BrNO3
Formula Weight
218
MOL File
27684-84-0.mol
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PHENOL, 5-BROMO-2-NITRO- Property

Melting point:
40-420C
Boiling point:
264.6±20.0 °C(Predicted)
Density 
1.881±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in ethyl acetate and methanol.
pka
6.08±0.13(Predicted)
form 
Crystalline Solid
color 
Pale yellow
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37-60
RIDADR 
2811
HS Code 
29089990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5788
Product name
5-Bromo-2-nitrophenol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$71
Updated
2025/07/31
TCI Chemical
Product number
B5788
Product name
5-Bromo-2-nitrophenol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$284
Updated
2025/07/31
TRC
Product number
B686258
Product name
5-Bromo-2-nitrophenol
Packaging
5g
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR30929
Product name
5-Bromo-2-nitrophenol
Purity
97%
Packaging
1g
Price
$18
Updated
2021/12/16
SynQuest Laboratories
Product number
4654-9-X8
Product name
5-Bromo-2-nitrophenol
Purity
97%
Packaging
1g
Price
$20
Updated
2021/12/16
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PHENOL, 5-BROMO-2-NITRO- Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

It is used as pharmaceutical intermediate.

Synthesis

591-20-8

27684-84-0

Potassium nitrate (51.5 g, 509 mmol) was slowly added to a mixed solution of concentrated sulfuric acid (32.6 mL) and water (105 mL) at 10 °C. The reaction mixture was stirred for 5 min and then 3-bromophenol (49.35 g, 285 mmol) was added dropwise while the reaction temperature was controlled to be maintained at about 10 °C. After addition, the reaction mixture was continued to be stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction solution was diluted with water (350 mL) and subsequently extracted with ether. The organic layers were combined, washed with saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography (silica gel, 19:1 hexane/ethyl acetate) to afford 5-bromo-2-nitrophenol (11.3 g, 18% yield) as a yellow-green solid. Its 1H NMR (DMSO-d6, 300 MHz) data were as follows: δ 11.44 (s, 1H), 7.84 (d, J = 8.7 Hz, 1H), 7.33 (d, J = 2.1 Hz, 1H), 7.18 (dd, J = 8.7, 2.1 Hz, 1H).

References

[1] Chemistry - A European Journal, 2011, vol. 17, # 33, p. 9076 - 9082
[2] European Journal of Medicinal Chemistry, 2012, vol. 56, p. 108 - 119
[3] Journal of Organic Chemistry, 1990, vol. 55, # 9, p. 2736 - 2742
[4] Patent: WO2011/44134, 2011, A1. Location in patent: Page/Page column 107
[5] Patent: EP1956013, 2008, A1. Location in patent: Page/Page column 37

PHENOL, 5-BROMO-2-NITRO- Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PHENOL, 5-BROMO-2-NITRO- manufacturers

Career Henan Chemical Co
Product
PHENOL, 5-BROMO-2-NITRO- 27684-84-0
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

27684-84-0, PHENOL, 5-BROMO-2-NITRO-Related Search:

2-NITRO 5-BROMO-BENZALDEHYDE 5-METHYL-2-NITROANILINE 2-nitro-6-chloroaniline 4,5-DICHLORO-2-NITROTOLUENE Benzene, 1-chloro-2-fluoro-4-methyl-5-nitro- 3-BROMO-5-HYDROXY-2,6-DINITRO-BENZOIC ACID 1-bromo-2,5-dimethoxy-4-nitrobenzene 4-bromo-2-methoxy-1-nitrobenzene 3-BROMO-5-METHOXY-2,6-DINITRO-BENZOIC ACID METHYL ESTER PHENOL, 5-BROMO-2-NITRO- 3-BROMO-5-BENZYLOXY-2,6-DINITROBENZOIC ACID BENZYL ESTER

  • PHENOL, 5-BROMO-2-NITRO-
  • 2-Nitro-5-bromophenol
  • 3-Bromo-6-nitrophenol
  • 5-Bromo-2-nitrophenol
  • 5-BroMo-2-nitrophenol, 97+%
  • 4-Bromo-2-hydroxynitrobenzene
  • 5-bromo-2-ntrophenol
  • 5-Bromo-2-nitrophenol 98%
  • 5-Bromo-2-nitrophenol, 96%,
  • 27684-84-0
  • Aromatics Compounds
  • Aromatics