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O-PHOSPHORYLETHANOLAMINE

Product Name
O-PHOSPHORYLETHANOLAMINE
CAS No.
1071-23-4
Chemical Name
O-PHOSPHORYLETHANOLAMINE
Synonyms
Pe 104;NSC 254167;NSC 25416);PHOSPHOCOLAMINE;Fosforilcolamine;O-PHOSPHOCOLAMINE;Colamine phosphate;Phsophorilcolamine;O-PHOSPHOCHOLAMINE;PHOSPHORYL COLAMINE
CBNumber
CB2478380
Molecular Formula
C2H8NO4P
Formula Weight
141.06
MOL File
1071-23-4.mol
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O-PHOSPHORYLETHANOLAMINE Property

Melting point:
241-243 °C(lit.)
Boiling point:
335.8±44.0 °C(Predicted)
Density 
1.554±0.06 g/cm3(Predicted)
storage temp. 
Store below +30°C.
Water Solubility 
Soluble in water
solubility 
PBS (pH 7.2): 10 mg/ml
pka
pK1:5.838(+1);pK2:10.638(0) (25°C)
form 
powder to crystal
color 
White to Light yellow
BRN 
1758916
InChIKey
SUHOOTKUPISOBE-UHFFFAOYSA-N
CAS DataBase Reference
1071-23-4(CAS DataBase Reference)
EPA Substance Registry System
Ethanol, 2-amino-, dihydrogen phosphate (ester) (1071-23-4)
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Safety

Hazard Codes 
T,C
Risk Statements 
25-34
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
KJ5830000
HazardClass 
8
PackingGroup 
III
HS Code 
29221990
Toxicity
LD50 orally in Rabbit: 5820 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P0503
Product name
O-Phosphorylethanolamine
Packaging
1g
Price
$22.7
Updated
2024/03/01
Sigma-Aldrich
Product number
P0503
Product name
O-Phosphorylethanolamine
Packaging
5g
Price
$34.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20061
Product name
2-Aminoethyl dihydrogen phosphate
Purity
for synthesis
Packaging
10g
Price
$53.9
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20061
Product name
2-Aminoethyl dihydrogen phosphate
Purity
for synthesis
Packaging
50g
Price
$168
Updated
2024/03/01
Sigma-Aldrich
Product number
73104
Product name
O-Phosphorylethanolamine
Purity
certified reference material, TraceCERT?
Packaging
100MG
Price
$101
Updated
2022/05/15
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O-PHOSPHORYLETHANOLAMINE Chemical Properties,Usage,Production

Chemical Properties

O-PHOSPHORYLETHANOLAMINE is white powder

Uses

O-PHOSPHORYLETHANOLAMINEe is used in the synthesis of Sphingomyelin, a type of sphingolipid found in animal cell membrane.

Uses

O-Phosphorylethanolamine has been used:

  • in LHC-8 medium as a supplement in culturing the transformed human liver epithelial (THLE)-2 and THLE-3 cells
  • in C-reactive protein (CRP) binding sucrose flotation experiment
  • to incubate phosphomonoesters with anion-exchange chromatography (AEC) fractions for the detection of phosphatase activity
  • to add in the washed beads for the preparation of phosphorylethanolamine (Pet) -conjugated sepharose column for chromatographic purification of mutant CRP

Definition

ChEBI: The ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain.

Biochem/physiol Actions

Phosphorylethanolamine participates in phospholipid metabolism. Its release can be stimulated occasionally by depolarizing stimuli. Reduction of phosphorylethanolamine levels has been observed in Alzheimer′s and Huntington′s disease.

Purification Methods

Purification by recrystallisation from aqueous EtOH gives a hydrate (m 140-141o). Its solubility in H2O is 17% and 0.003% in MeOH or EtOH at 22o. [F.lisch & .sterberg J Biol Chem 234 2298 1959, Baer & Staucer Can J Chem 34 434 1956, Christensen J Biol Chem 135 399 1940.] It is a potent inhibitor of ornithine decarboxylase [Gilad & Gilad Biochem Biophys Res Commun 122 277 1984]. [Beilstein 4 IV 1415.]

O-PHOSPHORYLETHANOLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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O-PHOSPHORYLETHANOLAMINE Suppliers

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View Lastest Price from O-PHOSPHORYLETHANOLAMINE manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
O-PHOSPHORYLETHANOLAMINE 1071-23-4
Price
US $36.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-16
Hebei Weibang Biotechnology Co., Ltd
Product
O-PHOSPHORYLETHANOLAMINE 1071-23-4
Price
US $1.00/PCS
Min. Order
1PCS
Purity
99%
Supply Ability
100mt
Release date
2024-11-01
airuikechemical co., ltd.
Product
O-phosphorylethanolamine 1071-23-4
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09

1071-23-4, O-PHOSPHORYLETHANOLAMINERelated Search:

ETHANOLAMINE HYDROCHLORIDE 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine Nadph tetrasodium salt 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHORYLETHANOLAMINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE NADP sodium salt ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 1,2-Distearoyl-sn-glycero-3-phosphocholine ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHORYLETHANOLAMINE 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Calcium phosphorylcholine chloride 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE O-PHOSPHORYLETHANOLAMINE Citicoline sodium CYTIDINE 2'-MONOPHOSPHATE 1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOETHANOLAMINE ETHYLPHOSPHONIC ACID

  • ETHANOLAMINE PHOSPHATE
  • 2-HYDROXYETHYLAMMONIUM DIHYDROGEN PHOSPHATE
  • 2-HYDROXYETHYLAMINE ACID PHOSPHATE
  • 2-AMINOETHANOL DIHYDROGEN PHOSPHATE
  • 2-AMINOETHYL DIHYDROGEN PHOSPHATE
  • O-PHOSPHOETHANOLAMINE
  • O-PHOSPHORYLETHANOLAMINE
  • O-PHOSPHOCOLAMINE
  • PHOSPHOCOLAMINE
  • PHOSPHOETHANOLAMINE
  • PHOSPHORYL COLAMINE
  • PHOSPHORYLETHANOLAMINE
  • MONOETHANOLAMINE ACID PHOSPHATE
  • 2-amino-ethanodihydrogenphosphate(ester)
  • 2-amino-ethanophosphate
  • Colamine phosphate
  • Colaminphosphoric acid
  • Ethanol, 2-amino-, dihydrogen phosphate
  • Ethanol, 2-amino-, dihydrogen phosphate (ester)
  • Ethanol, 2-amino-, phosphate
  • Ethanolamine O-phosphate
  • Mono(2-aminoethyl) phosphate
  • Pe 104
  • Phosphonoethanolamine
  • phosphoricacid,2-aminoethylphenylester
  • Phosphoryethanolamine
  • O-Phosphorylethanolamine,Phosphoryl colamine
  • O-PHOSPHORYLETHANOLAMINE CRYSTALLINE
  • O-Phosphorylethanolamine>99%
  • Phsophorilcolamine
  • 2-AMINOETHYL DIHYDROGEN PHOSPHATE 98+%
  • O-PHOSPHOCHOLAMINE
  • 2-Aminoethyl dihydrogen phosphate, O-Phosphocolamine, O-Phosphoethanolamine, Colaminephosphoric acid
  • O-Phosphocolamine, O-Phosphoethanolamine, O-Phosphorylethanolamine, Colamine phosphoric acid
  • 2-AMinoethanol 1-(Dihydrogen Phosphate)
  • 2-AMinoethanol Dihydrogen Phosphate Ester
  • 2-AMinoethanol O-Phosphate
  • 2-AMinoethanol Phosphate
  • MonoaMinoethyl Phosphate
  • NSC 254167
  • Phosphoric Acid 2-AMinoethyl Ester
  • Phosphoric acid dihydrogen 2-aminoethyl ester
  • <i>O</i>-Phosphorylethanolamine
  • COLAMINE ACID PHOSPHATE
  • COLAMINE PHOSPHORIC ACID
  • ETHANOLAMINE ACID PHOSPHATE
  • ETHANOLAMINE DIHYDROGEN PHOSPHATE
  • 2-ammonioethyl phosphate
  • O-Phosphoethanolamine Reference Material
  • O-Phosphoethanolamine Standard
  • O-Phosphorylethanolamine&gt
  • 2-AMINOETHYL DIHYDROGEN PHOSPHATE FOR SY
  • Ethanol, 2-amino-, 1-(dihydrogen phosphate)
  • Fosforilcolamine
  • NSC 25416)
  • Phosphoethanolamine (Monoaminoethyl phosphate
  • O-PHOSPHORYLETHANOLAMINE，2-AMINOETHANOL DIHYDROGEN PHOSPHAT
  • O-Phosphorylethanolamine, ≥ 98.0%