Canakinumab

Product Name: Canakinumab
CAS No.: 914613-48-2
Chemical Name: Canakinumab
Synonyms: ACZ885;Ilaris;ACZ-885;ACZ 885;Canakinumab;ACZ 885|||Ilaris;Canakinumab (Anti-IL-1b);Research Grade Canakinumab;Anti-Human IL-1B(Canakinumab);Research Grade Canakinumab(DHB95601)
CBNumber: CB24845962
Formula Weight: 0
MOL File: Mol file

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Canakinumab Property

storage temp.: Store at -20°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: ATB0023417
Product name: CANAKINUMAB
Purity: 95.00%
Packaging: 5MG
Price: $500.46
Updated: 2021/12/16

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Canakinumab Chemical Properties,Usage,Production

Uses

Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2].

References

[1] Dhimolea E. Canakinumab. MAbs. Epub 2010 Jan 15. DOI:10.4161/mabs.2.1.10328
[2] Rondeau JM, et al. The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β. MAbs. 2015;7(6):1151-60. DOI:10.1080/19420862.2015.1081323

Canakinumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Canakinumab Suppliers

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914613-48-2, CanakinumabRelated Search:

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Canakinumab

Anti-Human IL-1B(Canakinumab)

Research Grade Canakinumab(DHB95601)

ACZ 885

ACZ885

ACZ-885

Ilaris

Canakinumab (Anti-IL-1b)

ACZ 885|||Ilaris

Research Grade Canakinumab

Canakinumab - in PBS buffer approx. 15mg/ml

914613-48-2