Propargyl-PEG5-CH2CO2tBu

Product Name: Propargyl-PEG5-CH2CO2tBu
CAS No.: 2098489-63-3
Chemical Name: Propargyl-PEG5-CH2CO2tBu
Synonyms: Propargyl-PEG4-O-C1-Boc;Propargyl-PEG5-CH2CO2tBu;Propargyl-PEG5-CH2COOtBu;Propargyl-PEG5-CH2COOH t-Bu Ester;3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 1,1-dimethylethyl ester;tert-butyl 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]acetate;Propargyl-PEG4-CH2COOtBu/3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 1,1-dimethylethyl ester
CBNumber: CB24849647
Molecular Formula: C17H30O7
Formula Weight: 346.42
MOL File: 2098489-63-3.mol

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Propargyl-PEG5-CH2CO2tBu Property

Boiling point:: 406.8±40.0 °C(Predicted)
Density: 1.055±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Liquid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23857
Product name: Propargyl-PEG5-CH2CO2tBu
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-23857
Product name: Propargyl-PEG5-CH2CO2tBu
Purity: 98%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-23857
Product name: Propargyl-PEG5-CH2CO2tBu
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

Acrotein

Product number: B-1487
Product name: Propargyl-PEG4-CH2COOtBu
Purity: 97%
Packaging: 1g
Price: $366.67
Updated: 2021/12/16

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Propargyl-PEG5-CH2CO2tBu Chemical Properties,Usage,Production

Description

Propargyl-PEG5-CH2CO2tBu enables the formation of triazole linkages with azide compounds or biomolecules in copper catalyzed Click Chemistry reactions. The t-butyl group can be hydrolyzed under acidic conditions.

Uses

Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-O-C1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461. DOI:10.1021/acs.jmedchem.6b01781

Propargyl-PEG5-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG5-CH2CO2tBu Suppliers

China 18 United States 5 Global 23

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

TargetMol Chemicals Inc.

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Email: support@targetmol.com
Country: United States
ProdList: 39035
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Aladdin Scientific

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ProdList: 52923
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Combi-Blocks Inc.

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Country: United States
ProdList: 6618
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2098489-63-3, Propargyl-PEG5-CH2CO2tBuRelated Search:

2-(prop-2-ynyloxy)acetic acid 2-(2-Propyn-1-yloxy)acetic acid tert-butyl ester Propargyl-PEG5-CH2CO2H Propargyl-PEG5-CH2CO2-NHS Propargyl-PEG5-beta-D-galactose Acetylene-PEG5-acid Propargyl-PEG5-amine Proparyl-PEG5-methane Propargyl-PEG5-tetra-Ac-beta-D-galactose Propargyl-PEG5-alcohol

Propargyl-PEG5-CH2CO2tBu

Propargyl-PEG4-O-C1-Boc

3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 1,1-dimethylethyl ester

Propargyl-PEG5-CH2COOtBu

Propargyl-PEG5-CH2COOH t-Bu Ester

Propargyl-PEG4-CH2COOtBu/3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 1,1-dimethylethyl ester

tert-butyl 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]acetate

2098489-63-3