ChemicalBook > CAS DataBase List > Ethyl 4-aminocinnamate
Ethyl 4-aminocinnamate
- Product Name
- Ethyl 4-aminocinnamate
- CAS No.
- 5048-82-8
- Chemical Name
- Ethyl 4-aminocinnamate
- Synonyms
- Ethyl 4-aminocinnama;Ethyl 4-aminocinmate;4-AMINOETHYLCINNAMATE;ETHYL P-AMINOCINNAMATE;ETHYL 4-AMINOCINNAMATE;Ethyl 3-(4-aminophenyl);Ethyl4-aminocinnamate,97%;Ethyl 4-aminocinnamate 97%;Ethyl 3-(4-aMinophenyl)acrylate;4-AMINOCINNAMIC ACID ETHYL ESTER
- CBNumber
- CB2486905
- Molecular Formula
- C11H13NO2
- Formula Weight
- 191.23
- MOL File
- 5048-82-8.mol
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Ethyl 4-aminocinnamate Property
- Melting point:
- 70-74 °C (lit.)
- Boiling point:
- 347.0±25.0 °C(Predicted)
- Density
- 1.130±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 2.89±0.10(Predicted)
- Appearance
- Yellow to orange Solid
- BRN
- 2803541
- CAS DataBase Reference
- 5048-82-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethyl p-aminocinnamate(5048-82-8)
- EPA Substance Registry System
- 2-Propenoic acid, 3-(4-aminophenyl)-, ethyl ester (5048-82-8)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- E937873
- Product name
- Ethyl 4-aminocinnamate
- Packaging
- 5g
- Price
- $175
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0025373
- Product name
- ETHYL 4-AMINOCINNAMATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $648.81
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0025373
- Product name
- ETHYL 4-AMINOCINNAMATE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $852.21
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0025373
- Product name
- ETHYL 4-AMINOCINNAMATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1005.43
- Updated
- 2021/12/16
Crysdot
- Product number
- CD12067316
- Product name
- Ethyl3-(4-aminophenyl)acrylate
- Purity
- 97%
- Packaging
- 10g
- Price
- $135
- Updated
- 2021/12/16
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Ethyl 4-aminocinnamate Chemical Properties,Usage,Production
Synthesis
24393-61-1
5048-82-8
General procedure for the synthesis of ethyl 4-aminocinnamate from ethyl (E)-3-(4-nitrophenyl)acrylate: to an 8 mL glass vial (14 mm diameter, 50 mm height) equipped with a PTFE-coated oval magnetic stirring bar (8.5 mm) and a plastic screw cap was added ethyl (E)-3-(4-nitrophenyl)acrylate (0.5 mmol, 1.0 equivalents), Fe2O3/NGr(at)C catalyst (50 mg, 4.0 mol% Fe), triethylamine (Et3N, 70 μL, 0.5 mmol, 1.0 equivalents), tetrahydrofuran (THF, 2 mL) and deionized water (H2O, 0.2 mL). The silicone septum was punctured with a 26-gauge syringe needle (0.45 × 12 mm), and the vial was placed in an aluminum plate and transferred to a 300-mL autoclave. After sealing the autoclave, it was placed in an aluminum block and purged with carbon monoxide (CO, 5-10 bar) three times. This was followed by pressurization with CO to 30 bar and addition of nitrogen (N2) at 20 bar. The aluminum block was heated to 125°C with sufficient stirring (700 rpm). After 24 hours of reaction, the autoclave was removed from the aluminum block and cooled to room temperature. After releasing the remaining gas in a water bath, the vial containing the reaction mixture was removed. The reaction mixture was filtered through a diatomaceous earth pad (about 1 cm thick), the filtrate was concentrated and finally analyzed by gas chromatography (GC) and nuclear magnetic resonance (NMR) spectroscopy (Table 2).
References
[1] Advanced Synthesis and Catalysis, 2012, vol. 354, # 2-3, p. 321 - 327
[2] Synthesis (Germany), 2018, vol. 50, # 22, p. 4369 - 4376
[3] Journal of Organic Chemistry, 1999, vol. 64, # 7, p. 2301 - 2303
[4] Organic Letters, 2017, vol. 19, # 24, p. 6518 - 6521
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 19, p. 8967 - 9004
Ethyl 4-aminocinnamate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl 4-aminocinnamate manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- Ethyl 4-aminocinnamate 5048-82-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-25
Henan Fengda Chemical Co., Ltd
- Product
- Ethyl 4-aminocinnamate 5048-82-8
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-24
Career Henan Chemical Co
- Product
- Ethyl 4-aminocinnamate 5048-82-8
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10MT
- Release date
- 2018-12-21
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