Description
ChemicalBook > CAS DataBase List > Sulfamide

Sulfamide

Description
Product Name
Sulfamide
CAS No.
7803-58-9
Chemical Name
Sulfamide
Synonyms
SULFURIC DIAMIDE;SULPHAMIDE;SulfaMid;famide;NSC 252;SULFAMIDE;Suleamide;[S(NH2)2O2];Sulfamamide;Sulfamide >
CBNumber
CB2488651
Molecular Formula
H4N2O2S
Formula Weight
96.11
MOL File
7803-58-9.mol
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Sulfamide Property

Melting point:
90-92 °C(lit.)
Density 
1.611 g/mL at 25 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
water: soluble50mg/mL, clear, colorless to faintly yellow
form 
Crystalline Powder, Free From Visible Impurities
pka
10.87±0.60(Predicted)
color 
White to practically white , free from visible impurities
PH
5.67 at 21.7℃ and 10g/L
Water Solubility 
soluble
Sensitive 
Moisture Sensitive
Merck 
14,8922
InChIKey
NVBFHJWHLNUMCV-UHFFFAOYSA-N
CAS DataBase Reference
7803-58-9(CAS DataBase Reference)
NIST Chemistry Reference
Sulfamide(7803-58-9)
EPA Substance Registry System
Sulfamide (7803-58-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
F 
9
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
28530090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
211370
Product name
Sulfamide
Purity
99%
Packaging
5g
Price
$36.1
Updated
2024/03/01
Sigma-Aldrich
Product number
211370
Product name
Sulfamide
Purity
99%
Packaging
25g
Price
$85.8
Updated
2024/03/01
TCI Chemical
Product number
S0890
Product name
Sulfamide
Purity
>96.0%(N)
Packaging
25g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
S0890
Product name
Sulfamide
Purity
>96.0%(N)
Packaging
250g
Price
$141
Updated
2024/03/01
Alfa Aesar
Product number
A18680
Product name
Sulfamide
Purity
99%
Packaging
2.5g
Price
$45.65
Updated
2024/03/01
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Sulfamide Chemical Properties,Usage,Production

Description

Sulfamide is a white solid substance that is normally produced by reacting sulfuryl chloride with ammonia. Sulfamide is stable under normal conditions and soluble in acetone and DMSO. Sulfamide may also refer to the functional group in organic chemistry, and it consists of at least one group attached to a nitrogen atom of sulfamide.
It is a carbonic anhydrase inhibitor and is widely used as a pharmaceutical intermediate.
Sulfamide is sensitive to moisture, thus should be kept away from water and humidity. It should also be stored away from oxidizing agents. Sulfamide should be kept in a tightly closed container and placed in a cool, dry, and well-ventilated condition.

Chemical Properties

White Solid

Uses

Sulfamide and its derivatives can also be used to prepare fused thiadiazine systems, Reaction with 2-aminoacetophenones affords IH-2,1,3-benzothia- diazine 2,2-dioxides 77 (65JOC3960). The corresponding 3,4-dihydro deriv- atives are readily available from 2-aminobenzylamines with either sulfuryl chloride (70M1443) or sulfamide (66USP3278532; 71MI055). These kinds of compounds can also be obtained from N-aryl-N'-alkylsulfamides and s-trioxane in a reaction involving cyclization by intramolecular sulfamido- methylation (79JOC2032) (Scheme 30).

Uses

Similar to urea in many of its reactions, but is more acidic, and can act as a dibasic acid.

Uses

A carbonic anhydrase inhibitor; used for treatment of cancer.

Definition

ChEBI: The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to two amino groups and by double bonds to two oxygen atoms.

Purification Methods

Crystallise sulfamide from absolute EtOH. It decomposes at 250o. [Schenk in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I pp 482-483 1963.]

Sulfamide Preparation Products And Raw materials

Raw materials

Sulfuryl chloride Ammonia

Preparation Products

Famotidine N-SULPHAMYL-3-CHLOROPROPIONAMIDINE (5-CHLORO-1-BENZOTHIOPHEN-3-YL)METHYLAMINE
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Sulfamide Suppliers

Belgium 2 Canada 2 China 290 Europe 2 Germany 6 India 15 Japan 3 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 13 United States 45 Global 383
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View Lastest Price from Sulfamide manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Sulfamide 7803-58-9
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99% HPLC
Supply Ability
2000tons
Release date
2019-12-30
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Sulfamide 7803-58-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-13
Baoji Guokang Bio-Technology Co., Ltd.
Product
Sulfamide 7803-58-9
Price
US $825.00/KG
Min. Order
25KG
Purity
99%
Supply Ability
2000T
Release date
2021-06-07

7803-58-9, SulfamideRelated Search:

Famotidine p-Toluenesulfonamide Sulfamethazine [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) FAMOTIDINE RELATED COMPOUND B 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 3-Chloropropiononitrile 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoylpropanamidine FaMotidine Acid IMpurity 3-Hydroxypropionic acid N-DesaMinosulfonyl-N-cyano FaMotidine FaMotidine Acid IMpurity Methyl Ester 3-HYDROXYPROPIONAMIDE

  • Sulfamamide
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  • SulfaMide, 98+% 5GR
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  • SULFAMIDE(4-HYDROXY-2-METHYL-2H-1,2-BENZOISOTHIAZOL-2-ACETICETHER-1,1-DIOXIDE)
  • Sulfuryl amine
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  • NSC 252
  • Sulfonyl Diamide
  • Sulfuryl Diamide
  • SULFAMIDE ( SULFURYL AMIDE )
  • Sulfamide &gt
  • Sulfamide, 99%, for synthesis
  • Famotidine Impurity 15
  • Sulfamide ISO 9001：2015 REACH
  • Sulfamide (6CI, 8CI, 9CI, ACI)
  • C16998170 Sulfamide
  • 7803-58-9
  • SO2NH22
  • NH22SO2
  • H4N2O2S
  • Pharmaceutical intermediates
  • Inhibitors
  • Sulfur & Selenium Compounds
  • Electronic Chemicals
  • Micro/Nanoelectronics
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  • Starting Raw Materials & Intermediates
  • Chemical Amines
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