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N-(2-Oxoethyl)phthalimide

Product Name
N-(2-Oxoethyl)phthalimide
CAS No.
2913-97-5
Chemical Name
N-(2-Oxoethyl)phthalimide
Synonyms
2-(1,3-DIOXOISOINDOLIN-2-YL)ACETALDEHYDE;NSC 30242;PHTHALIMIDOACETALDEHYDE;N-(2-Formyl)phthalimide;Rucaparib Intermediate 1;Phthalylglycine aldehyde;N-(2-OXOETHYL)PHTHALIMIDE;2-PHTHALIMIDOACETALDEHYDE;2-Phthalimidylacetaldehyde;Phthalimidoacetaldehyde>
CBNumber
CB2496913
Molecular Formula
C10H7NO3
Formula Weight
189.17
MOL File
2913-97-5.mol
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N-(2-Oxoethyl)phthalimide Property

Melting point:
116-118°C
Boiling point:
324.3±25.0 °C(Predicted)
Density 
1.376±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly, Heated, Sonicated), Ethyl Acetate (Slightly)
form 
Solid
pka
-2.45±0.20(Predicted)
color 
White to Pale Yellow
InChI
InChI=1S/C10H7NO3/c12-6-5-11-9(13)7-3-1-2-4-8(7)10(11)14/h1-4,6H,5H2
InChIKey
LMRDBJZQDUVCQH-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(=O)N1CC=O
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Safety

RTECS 
TI5125000
HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2010
Product name
Phthalimidoacetaldehyde
Purity
>98.0%(N)
Packaging
1g
Price
$65
Updated
2025/07/31
TCI Chemical
Product number
P2010
Product name
Phthalimidoacetaldehyde
Purity
>98.0%(N)
Packaging
5g
Price
$211
Updated
2025/07/31
TRC
Product number
P384500
Product name
Phthalimidoacetaldehyde
Packaging
5g
Price
$950
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0014840
Product name
PHTHALIMIDOACETALDEHYDE
Purity
95.00%
Packaging
1G
Price
$983.52
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0014840
Product name
PHTHALIMIDOACETALDEHYDE
Purity
95.00%
Packaging
2.5G
Price
$1473.14
Updated
2021/12/16
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N-(2-Oxoethyl)phthalimide Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Phthalimidoacetaldehyde (cas# 2913-97-5) is a compound useful in organic synthesis.

Synthesis

78902-09-7

2913-97-5

Example 5: Preparation of N-2-[4-(4-bromo-2-fluorophenylamino)-7-(1-methylpiperidin-4-ylmethoxy)-quinazolin-6-ylamino]-ethyl-propenamide Step 5-1: Synthesis of 1,3-dioxo-1,3-dihydroisoindol-2-yl acetaldehyde Phthalimidoacetaldehyde diethyl acetal (10 g, 0.0379 mol) was dissolved in 100 mL of aqueous 1N HCl, refluxed and stirred for 1 hour. Upon completion of the reaction, the reaction solution was extracted with 200 mL of dichloromethane, followed by washing the organic layer with 100 mL of saturated saline. The solvent was removed by distillation under reduced pressure to give N-(2-acetaldehyde-based) phthalimide 7.16 g (yield: 99%). 1H NMR (CDCl3) δ: 9.66 (s, 1H), 7.90-7.84 (m, 2H), 7.78-7.73 (m, 2H), 4.56 (s, 2H).

References

[1] Tetrahedron, 2002, vol. 58, # 9, p. 1719 - 1737
[2] Tetrahedron, 2008, vol. 64, # 28, p. 6794 - 6800
[3] Patent: WO2007/55513, 2007, A1. Location in patent: Page/Page column 29
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 33, p. 9668 - 9672
[5] Angew. Chem., 2015, vol. 127, # 33, p. 9804 - 9808,5

N-(2-Oxoethyl)phthalimide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-Oxoethyl)phthalimide Suppliers

Canada 1 China 193 Germany 4 India 4 Japan 1 Switzerland 1 United States 18 Global 222
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from N-(2-Oxoethyl)phthalimide manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N-(2-Oxoethyl)phthalimide 2913-97-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Shanghai UCHEM Inc.
Product
N-(2-Oxoethyl)phthalimide 2913-97-5
Price
US $349.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
25kg
Release date
2023-11-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-(2-oxoethyl)phthalimide 2913-97-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

2913-97-5, N-(2-Oxoethyl)phthalimideRelated Search:

Succinimide 4-Aminophthalimide Maleimide O-Phthalimide 3-Nitrophthalimide 4-Nitrophthalimide Potassium phthalimide Acetaldehyde Bismaleimide N-Hydroxyphthalimide N-Methylphthalimide N-(2-Hydroxy-2-oxoethyl)phthalimide DIALIFOS N-(2-Chloro-2-oxoethyl)phthalimide N-PHTHALOYLGLYCINEAMIDE PHT-LEU-OH 2-PHTHALIMIDOPROPIONIC ACID 2-PHTHALIMIDOGLUTARANILIC ACID

  • N-phthalimidyl-2-aminoacetaldehyde
  • (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetaldehyde
  • [(1,3-Dioxo-1,3-dihydro-2H-isoindole)-2-yl]acetaldehyde
  • 1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetaldehyde
  • 2-Phthalimidylacetaldehyde
  • 2-(1,3-Dioxoisoindol-2-yl)ethanal
  • 2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)acetaldehyde
  • NSC 30242
  • 2-(1,3-diketoisoindolin-2-yl)acetaldehyde
  • 2-(1,3-dioxoisoindol-2-yl)acetaldehyde
  • dimethyl acetal of phthalimidoacetaldehyde
  • (1,3-Dioxo-1,3-dihydroisoindol-2-yl)
  • 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetaldehyde
  • 2H-Isoindole-2-acetaldehyde,1,3-dihydro-1,3-dioxo-
  • 2-(1,3-Dioxo-2-isoindolinyl)acetaldehyde
  • Rucaparib Intermediate 1
  • (1,3-DIOXO-1,3-DIHYDROISOINDOL-2-YL)ACETALDEHYDE
  • 1,3-DIOXO-2-ISOINDOLINEACETALDEHYDE
  • 2-(1,3-DIOXOISOINDOLIN-2-YL)ACETALDEHYDE
  • N-(2-OXOETHYL)PHTHALIMIDE
  • N-(FORMYLMETHYL)PHTHALIMIDE
  • n-(formylmethyl)-phthalimid
  • PHTHALIMIDOACETALDEHYDE
  • 2-PHTHALIMIDOACETALDEHYDE
  • N - (2-acetaldehyde) phthalimide
  • Phthalimidoacetaldehyde&gt
  • Phthalylglycine aldehyde
  • PHTHALIMIDOACETALDEHYDE 98%
  • N-(2-Formyl)phthalimide
  • 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-acetaldehyde
  • 2913-97-5
  • Aromatics Compounds
  • Aromatics
  • Cross Linking Reagents
  • Heterocycles
  • Miscellaneous Reagents
  • 2913-97-5