2-BROMO-5-METHOXYBENZYL BROMIDE 97
- Product Name
- 2-BROMO-5-METHOXYBENZYL BROMIDE 97
- CAS No.
- 19614-12-1
- Chemical Name
- 2-BROMO-5-METHOXYBENZYL BROMIDE 97
- Synonyms
- Atogepant Impurity 33;2-bromo-5-methoxybromobenzyl;4-Bromo-3-bromomethyl anisole;2-Bromo-5-methyoxybenzyl bromide;5-BroMo-2-Methoxy Benzyl BroMide;2-BROMO-5-METHOXYBENZYL BROMIDE 97;2-Bromo-5-methoxybenzyl Bromide >2-Bromo-5-methoxybenzyl bromide 97%;Benzene, 1-bromo-2-(bromomethyl)-4-methoxy-
- CBNumber
- CB2499808
- Molecular Formula
- C8H8Br2O
- Formula Weight
- 279.96
- MOL File
- 19614-12-1.mol
2-BROMO-5-METHOXYBENZYL BROMIDE 97 Property
- Melting point:
- 90-94 °C (lit.)
- Boiling point:
- 299.6±25.0 °C(Predicted)
- Density
- 1.759±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Solid
- color
- White to beige
- Water Solubility
- Soluble in hot methanol. Slightly soluble in water.
- InChI
- InChI=1S/C8H8Br2O/c1-11-7-2-3-8(10)6(4-7)5-9/h2-4H,5H2,1H3
- InChIKey
- MURVUTUZSUEIGI-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=C(OC)C=C1CBr
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- Ⅱ
- HS Code
- 2909303890
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 553387
- Product name
- 2-Bromo-5-methoxybenzyl bromide
- Purity
- 97%
- Packaging
- 25g
- Price
- $143
- Updated
- 2023/06/20
- Product number
- B4423
- Product name
- 2-Bromo-5-methoxybenzyl Bromide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $56
- Updated
- 2025/07/31
- Product number
- B4423
- Product name
- 2-Bromo-5-methoxybenzyl Bromide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $221
- Updated
- 2025/07/31
- Product number
- B696633
- Product name
- 2-Bromo-5-methoxybenzyl bromide
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- B696633
- Product name
- 2-Bromo-5-methoxybenzyl bromide
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
2-BROMO-5-METHOXYBENZYL BROMIDE 97 Chemical Properties,Usage,Production
Uses
Employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field
Synthesis
27060-75-9
19614-12-1
The general procedure for the synthesis of 2-bromo-5-methoxybenzyl bromide from 2-bromo-5-methoxytoluene was as follows: 2-bromo-5-methoxytoluene (0.050 mol) and N-bromosuccinimide (NBS, 0.055 mol) were dissolved in carbon tetrachloride (125 mL), and azobisisobutyronitrile (AIBN, 0.001 mol) was added as initiator. The reaction mixture was stirred at 80 °C for 18 hours. Upon completion of the reaction, the mixture was diluted with hexane and subsequently filtered through a diatomaceous earth pad to remove insoluble impurities. The filtrate was concentrated under reduced pressure to remove the solvent and the residue was washed with ethyl acetate to give the final target product 4-bromo-3-(bromomethyl)anisole.
References
[1] Tetrahedron, 2004, vol. 60, # 49, p. 11075 - 11087
[2] Journal of the American Chemical Society, 2005, vol. 127, # 29, p. 10124 - 10125
[3] Journal of Organic Chemistry, 2014, vol. 79, # 11, p. 4973 - 4983
[4] Synlett, 2011, # 17, p. 2525 - 2528
[5] Journal of Medicinal Chemistry, 2000, vol. 43, # 1, p. 22 - 26
2-BROMO-5-METHOXYBENZYL BROMIDE 97 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-5-METHOXYBENZYL BROMIDE 97 manufacturers
- Product
- 2-BROMO-5-METHOXYBENZYL BROMIDE 97 19614-12-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-13
- Product
- 2-BROMO-5-METHOXYBENZYL BROMIDE 19614-12-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-22
- Product
- 2-BROMO-5-METHOXYBENZYL BROMIDE 97 19614-12-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-26