4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE

Product Name: 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
CAS No.: 6345-27-3
Chemical Name: 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
Synonyms: 4-AmidinopyridiniumHCl;Pyridin-4-carboximidamide HCl;IsonicotiniMidaMide hydrochloride;4-Amidinopyridinium chloride, 98+%;4-pyridin-carbamidine hydrochloride;4-pyridinecarboxamidine hydrochloride;4-AMIDINOPYRIDINE HYDROCHLORIDE, 98+%;4-Amidinopyridine hydrochloride ydrochloride;4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE;Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochlo
CBNumber: CB2500438
Molecular Formula: C12H16Cl2N6
Formula Weight: 315.20164
MOL File: 6345-27-3.mol

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4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Property

Melting point:: 240-242°C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: White to off-white Solid
Sensitive: Hygroscopic
BRN: 3562678
InChI: InChI=1S/2C6H7N3.2ClH/c2*7-6(8)5-1-3-9-4-2-5;;/h2*1-4H,(H3,7,8);2*1H
InChIKey: YXRVCYDHRUUPFU-UHFFFAOYSA-N
SMILES: C1N=CC=C(C(=N)N)C=1.[H]Cl.C1N=CC=C(C(N)=N)C=1.[H]Cl
CAS DataBase Reference: 6345-27-3

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37
Hazard Note: Irritant
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: P840418
Product name: Pyridine-4-carboximidamideHydrochloride
Packaging: 100mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: C182
Product name: 4-Amidinopyridiniumhydrochloride
Packaging: 100g
Price: $427
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK621783
Product name: 4-Amidinopyridinehydrochloride
Purity: 98%
Packaging: 1g
Price: $28
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H41-5-X1
Product name: Pyridine-4-carboxamidine hydrochloride
Packaging: 5G
Price: $44
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H41-5-X1
Product name: Pyridine-4-carboxamidine hydrochloride
Packaging: 1g
Price: $16
Updated: 2021/12/16

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4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis

100-48-1

6345-27-3

The general procedure for the synthesis of 4-formamidopyridine hydrochloride from 4-cyanopyridine was as follows: 4-cyanopyridine (20.0 g, 0.2 mol) was dissolved in anhydrous methanol (200 mL), followed by a one-time addition of powdered sodium methanol (1.1 g, 20 mmol). The reaction mixture was stirred at room temperature overnight. Next, ammonium chloride (16.5 g, 0.31 mol) was added and the reaction mixture was heated to reflux for 4 hours, after which it was cooled to room temperature. The solvent was removed by evaporation, anhydrous ethanol (300 mL) was added, and the mixture was subsequently heated to reflux. after 15 min, the solid insoluble material was removed by filtration, and the filtrate was cooled to room temperature and allowed to stand overnight. The filtrate was filtered again to remove additional inorganic salts and finally the reaction mixture was concentrated to about one-third of the original volume, which was filtered to give 24.0 g of 4-formamidinopyridine hydrochloride in 76% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 15, p. 3487 - 3490
[2] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 11, p. 3347 - 3356
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 12, p. 2990 - 2993
[4] Journal of Medicinal Chemistry, 1990, vol. 33, # 4, p. 1230 - 1241
[5] Patent: US5294612, 1994, A

4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Suppliers

China 75 France 1 Germany 4 India 3 Switzerland 1 United Kingdom 7 United States 16 Global 107

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View Lastest Price from 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE 6345-27-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-08

6345-27-3, 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDERelated Search:

Benzamidine hydrochloride PYRIDINE-2-CARBOXAMIDE 3-(2-PYRIDYL)ACRYLIC ACID Pyridine hydrofluoride 2,4-Pyridinedicarboxylic acid, 2-Methyl ester 4-METHYLPHTHALIMIDE Formamidine hydrochloride 4-PYRIDINECARBOXAMIDINE 4-AMIDINOPYRIDINIUM CHLORIDE Pyridine-2-carboximidamide hydrochloride 3-AMIDINOPYRIDINIUM CHLORIDE

4-AMIDINOPYRIDINE HYDROCHLORIDE, 98+%

4-pyridin-carbamidine hydrochloride

IsonicotiniMidaMide hydrochloride

Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochloride, Pyridine-4-carboxamidine hydrochloride

4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE

4-Amidinopyridinium chloride, 98+%

4-AmidinopyridiniumHCl

4-pyridinecarboxamidine hydrochloride

Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochlo

4-Amidinopyridine hydrochloride ydrochloride

Pyridin-4-carboximidamide HCl

6345-27-3

C6H10ClN3O