ChemicalBook > CAS DataBase List > Terminolic acid
Terminolic acid
- Product Name
- Terminolic acid
- CAS No.
- 564-13-6
- Chemical Name
- Terminolic acid
- Synonyms
- Terminolic acid;Terminolic acid, 10 mM in DMSO;2α,6β,23-trihydroxyl oleanolic acid;2α,6β,23-trihydroxyl oleanolic acid;Olean-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2a,3b,4a,6b)-;Olean-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-;racemosum,glucoside,Terminolic acid,Inhibitor,IL-1β,antibacterial,Bacterial,IL-6,triterpenoid,IL-4,inhibit,cytokines,inflammatory,pentacyclic,Combretum;(4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
- CBNumber
- CB25832286
- Molecular Formula
- C30H48O6
- Formula Weight
- 504.7
- MOL File
- 564-13-6.mol
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Terminolic acid Property
- Melting point:
- 332-334 °C
- Boiling point:
- 638.1±55.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 4.59±0.70(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0134972
- Product name
- Terminolicacid
- Packaging
- 1mg
- Price
- $200
- Updated
- 2021/12/16
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Terminolic acid Chemical Properties,Usage,Production
Uses
Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity[1][1].
References
[1] Gossan DPA, et, al. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95. DOI:10.1016/j.fitote.2016.03.002
[2] Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147.
Terminolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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