Piperazine-2-carboxylic acid

Product Name: Piperazine-2-carboxylic acid
CAS No.: 2762-32-5
Chemical Name: Piperazine-2-carboxylic acid
Synonyms: DS-1093;DS-1043;PRZCA-2HCL;TIMTEC-BB SBB003518;2-Piperazinecarboxyl;piperazine-2-carboxylicaci;PIPERAZINE-2-CARBOXYLIC ACID;(±)-Piperazine-2-carboxylic acid;PIPERAZINE-2-CARBOXYLIC ACID 2HCL;(^+)-Piperazine-2-carboxylic acid
CBNumber: CB2663395
Molecular Formula: C5H10N2O2
Formula Weight: 130.15
MOL File: 2762-32-5.mol

More

Less

Piperazine-2-carboxylic acid Property

Melting point:: 265 °C (dec.)(lit.)
Boiling point:: 313.6±37.0 °C(Predicted)
Density: 1.174
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 1.90±0.20(Predicted)
Appearance: White to yellow Solid
optical activity: Consistent with structure
InChI: InChI=1S/C5H10N2O2/c8-5(9)4-3-6-1-2-7-4/h4,6-7H,1-3H2,(H,8,9)
InChIKey: JSSXHAMIXJGYCS-UHFFFAOYSA-N
SMILES: N1CCNCC1C(O)=O
CAS DataBase Reference: 2762-32-5(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2933599590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P991853
Product name: Piperazine-2-carboxylicAcid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J98649
Product name: Piperazine-2-carboxylicacid
Packaging: 5g
Price: $10
Updated: 2021/12/16

AK Scientific

Product number: W5067
Product name: Piperazine-2-carboxylicacid
Packaging: 25g
Price: $34
Updated: 2021/12/16

ChemScene

Product number: CS-W002409
Product name: Piperazine-2-carboxylicacid
Purity: >98.0%
Packaging: 100g
Price: $61
Updated: 2021/12/16

Matrix Scientific

Product number: 074978
Product name: Piperazine-2-carboxylic acid
Purity: 95+%
Packaging: 5g
Price: $70
Updated: 2021/12/16

More

Less

Piperazine-2-carboxylic acid Chemical Properties,Usage,Production

Uses

Piperazine-2-carboxylic acid is an important organic compound used as a basic structural component of pharmaceutical intermediates. Studies have shown that Piperazine-2-carboxylic acid derivatives are a potential multi-targeted ligands (MTDLs) anti-Alzheimer's disease (AD) active ingredient.

Synthesis

98-97-5

2762-32-5

Step 1: Preparation of piperazine-2-carboxylic acid: pyrazine-2-carboxylic acid (102.7 g, 0.827 mol) was dissolved in water (600 mL), sodium hydroxide (66 g, 1.65 mol) and 20% palladium/carbon catalyst (5.0 g) were added. The hydrogenation reaction was carried out under hydrogen atmosphere for 15 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated. Concentrated hydrochloric acid was added to the concentrate and a white precipitate precipitated. The solid was washed with cold water, collected by filtration and dried under vacuum to give 137.2 g of piperazine-2-carboxylic acid hydrochloride (99.6% yield). Mass spectrum (MS): m/z 131 (corresponding to C5H10N2O2, [M+H]+).

References

[1] Tetrahedron Letters, 1989, vol. 30, # 39, p. 5193 - 5196
[2] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 8, p. 1121 - 1126
[3] Patent: US6251919, 2001, B1

Piperazine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Piperazine-2-carboxylic acid Suppliers

Belgium 1 China 147 Europe 2 Germany 5 India 6 Japan 1 The Netherlands 1 United Kingdom 7 United States 23 Global 193

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

Rintech, Inc.

Tel: --
Fax: --
Email: info@rintechinc.com
Country: United States
ProdList: 3416
Advantage: 60

Combi-Blocks, Inc.

Tel: --
Fax: --
Email: les@combi-blocks.com
Country: United States
ProdList: 2555
Advantage: 58

Fluorochem Ltd.

Tel: --
Fax: --
Email: enquiries@fluorochem.co.uk
Country: United States
ProdList: 4583
Advantage: 58

AstaTech, Inc.

Tel: --
Fax: --
Email: sales@astatechinc.com
Country: United States
ProdList: 904
Advantage: 58

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Accela ChemBio Inc.

Tel: --
Fax: --
Email: info@accelachem.com
Country: United States
ProdList: 1054
Advantage: 50

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

CNH Technologies, Inc.

Tel: --
Fax: --
Email: info@cnhtechnologies.com
Country: United States
ProdList: 353
Advantage: 42

Ring Specialty Chemicals Inc.

Tel: --
Fax: --
Email: info@ringchemicals.com
Country: United States
ProdList: 888
Advantage: 39

EJY Tech, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 448
Advantage: 30

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

AstaTech, Inc

Tel: --
Fax: --
Email: sales@astatechinc.com
Country: United States
ProdList: 6371
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Louston International

Tel: --
Fax: --
Email: sales@louston.com
Country: United States
ProdList: 525
Advantage: 58

ECA International Corporation

Tel: --
Fax: --
Email: services@ecacorporation.com
Country: United States
ProdList: 1062
Advantage: 52

More

Less

View Lastest Price from Piperazine-2-carboxylic acid manufacturers

Shanghai Xinchem Co., Ltd.

Product: Piperazine-2-carboxylic acid 2762-32-5
Price: US $0.00-0.00/drums
Min. Order: 1drums
Purity: 99%min.
Supply Ability: 10tons
Release date: 2023-10-22

Dideu Industries Group Limited

Product: 2-Piperazinecarboxylic acid dihydrochloride 2762-32-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-24

Career Henan Chemical Co

Product: 2-Piperazinecarboxylic acid dihydrochloride 2762-32-5
Price: US $8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-25

2762-32-5, Piperazine-2-carboxylic acidRelated Search:

2,6-piperidinedicarboxylic acid DL-Pipecolinic acid Piperazine-2-carboxylic acid dihydrochloride Piperacillin N-Aminoethylpiperazine Piperazine 2-Ethylhexyl ferulate Homopiperazine 1-Methylpiperazine (S)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE 98% (R)-(+)-2-Piperazinecarboxylic acid dihydrochloride PIPERAZINE-2-CARBOXYLIC ACID 2-PIPERAZINECARBOXYLIC ACID, DIHYDROCHLORIDE, (2S)-,(S)-(-)-2-PIPERAZINECARBOXYLIC ACID DIHYDROCHLORIDE (S)-Piperazine-2-carboxylic acid dihydrochloride 4-METHYL-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE 1-PHENYL-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE 2-Piperazinecarboxylic acid dihydrochloride Piperazinecarboxylic Acid Dihydrochloride

2-Piperazinecarboxyl

(^+)-Piperazine-2-carboxylicacid,98%

PRZCA-2HCL

(+/-)-PIPERAZINE-2-CARBOXYLIC ACID 2HCL

PIPERAZINE-2-CARBOXYLIC ACID 2HCL

PIPERAZIN-2-CARBOXYLIC ACID DIHYDROCHLORIDE

TIMTEC-BB SBB003518

Piperazine-2-carboxylic acid dihydrochloride

2-Piperazinecarboxylic acid dihydrochloride

piperazine-2-carboxylicaci

2-Piperazinecarboxylic acid dihydrochloride ISO 9001：2015 REACH

(^+)-Piperazine-2-carboxylic acid

PIPERAZINE-2-CARBOXYLIC ACID

Piperazine-2-carboxylic acid, 97%

(±)-Piperazine-2-carboxylic acid

DS-1093

DS-1043

2762-32-5