H-D-PHG-OME HCL

Product Name: H-D-PHG-OME HCL
CAS No.: 19883-41-1
Chemical Name: H-D-PHG-OME HCL
Synonyms: 2-phenylglycine methyl ester hydrochloride;D-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE;(R)-Methyl 2-aMino-2-phenylacetate hydrochloride;Methyl (R)-2-Amino-2-Phenylacetate Hydrochloride;methyl (2R)-2-amino-2-phenylacetate hydrochloride;T0400-4069;D-Peg-Oe.H Cl;H-D-PHG-OME HCL;H-D-Phg · OCH3 · HCl;Cephalexin Impurity 1
CBNumber: CB2664271
Molecular Formula: C9H12ClNO2
Formula Weight: 201.65
MOL File: 19883-41-1.mol

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H-D-PHG-OME HCL Property

Melting point:: 189-191 °C(lit.)
alpha: -118o (C=1 IN H2O)
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder to crystal
color: White to Almost white
optical activity: [α]20/D 118°, c = 1 in H2O
BRN: 3915654
InChI: InChI=1/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/s3
InChIKey: DTHMTBUWTGVEFG-DDWIOCJRSA-N
SMILES: C(OC)(=O)[C@H](C1=CC=CC=C1)N.[H]Cl |&1:4,r|
CAS DataBase Reference: 19883-41-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26-36/37
WGK Germany: 3
HS Code: 29224999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 307882
Product name: (R)-(?)-2-Phenylglycine methyl ester hydrochloride
Purity: ≥95%
Packaging: 25g
Price: $53.9
Updated: 2023/01/07

Sigma-Aldrich

Product number: 307882
Product name: (R)-(?)-2-Phenylglycine methyl ester hydrochloride
Purity: ≥95%
Packaging: 100g
Price: $149
Updated: 2023/01/07

TCI Chemical

Product number: P2592
Product name: D-(-)-2-Phenylglycine Methyl Ester Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $33
Updated: 2025/07/31

TRC

Product number: P327235
Product name: (R)-(?)-2-Phenylglycine methyl ester hydrochloride
Packaging: 5g
Price: $60
Updated: 2021/12/16

Chem-Impex

Product number: 05997
Product name: D-Phenylglycinemethylesterhydrochloride,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 25G
Price: $42.56
Updated: 2021/12/16

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H-D-PHG-OME HCL Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

(R)-(-)-2-Phenylglycine Methyl Ester Hydrochloride is an intermediate in the synthesis of Cephradine, a cephalosporin antibiotic. It functions as an acyl donor in the enzymatic synthetic process for cephradine synthesis.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

67-56-1

875-74-1

19883-41-1

Methylation reaction of L-phenylglycine. L-phenylglycine (1 g, 6.05 mmol, 1.0 eq.) was suspended in methanol (25 mL) and cooled to 0°C. Thionyl chloride (475 μL, 6.66 mmol, 1.5 eq.) was slowly added. after 10 min, the reaction mixture was heated to 75 °C and refluxed for 2 h. The reaction was completed by TLC. After completion of the reaction (monitored by TLC), the solvent was removed under vacuum to give a white solid, L-phenylglycine methyl ester hydrochloride (1.23 g, quantitative yield).

References

[1] Tetrahedron, 1999, vol. 55, # 11, p. 3337 - 3354
[2] European Journal of Organic Chemistry, 2009, # 30, p. 5185 - 5191
[3] European Journal of Medicinal Chemistry, 2018, vol. 145, p. 649 - 660
[4] Tetrahedron, 2009, vol. 65, # 6, p. 1200 - 1206
[5] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992, # 8, p. 1279 - 1285

H-D-PHG-OME HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-D-PHG-OME HCL Suppliers

China 350 Germany 5 India 18 Japan 4 South Korea 1 Switzerland 1 United Kingdom 1 United States 24 Global 404

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View Lastest Price from H-D-PHG-OME HCL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-(-)-2-Phenylglycine methyl ester hydrochloride 19883-41-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-07

Hebei Chuanghai Biotechnology Co., Ltd

Product: H-D-PHG-OME HCL 19883-41-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-28

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: H-D-Phg-OMe·HCl 19883-41-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-04-03

19883-41-1, H-D-PHG-OME HCLRelated Search:

Di-tert-butyl peroxide Glycine ethyl ester hydrochloride Sodium iodide Glycine methyl ester hydrochloride ETHYL (R)-(-)-MANDELATE (R)-4-CHLORO PHENYLGLYCINE H-D-PHG-OTBU HCL D(-)-Phenylglycinamide H-D-Phg-Gly-OH METHYL (2R)-2-AMINO-3-(2-CHLORO(4-PYRIDYL))PROPANOATE METHYL (2R)-2-AMINO-3-(2,6-DICHLORO(3-PYRIDYL))PROPANOATE METHYL (2R)-2-AMINO-3-(2,6-DIFLUOROPYRIDIN-3-YL)PROPANOATE METHYL (2R)-2-AMINO-3-(2,6-DIMETHYL(3-PYRIDYL))PROPANOATE methyl (R)-aminophenylacetate methyl (2R)-2-amino-3-(2-fluorophenyl)propanoate hydrochloride METHYL (2R)-2-AMINO-3-(2-AMINO-4-FLUOROPHENYL)PROPANOATE (Z)-Cefdinir Cefdinir Impurity E

Methyl α-aMinophenylacetate HCl

(R)-Methyl 2-aMino-2-phenylacetate hydrochloride

(2-keto-2-methoxy-1-phenyl-ethyl)ammonium chloride

(2-methoxy-2-oxo-1-phenylethyl)ammonium chloride

(2-methoxy-2-oxo-1-phenyl-ethyl)ammonium chloride

(2-methoxy-2-oxo-1-phenylethyl)azanium chloride

(2-methoxy-2-oxo-1-phenyl-ethyl)azanium chloride

methyl amino(phenyl)acetate hydrochloride

T0400-4069

H-D-Phg · OCH3 · HCl

(R)-(-)-2-Phenylglycine Methyl ester hydrochloride >=95%

methyl 2-azanyl-2-phenyl-ethanoate

(R)-(-)-2-Phenylglycine methyl ester hydrochloride -()-2-Phenylglycine methyl ester hydrochloride ,98%

D-(-)-2-Phenylglycine Methyl ester hydrochloride, 96%

D-Peg-Oe.H Cl

Cephalexin Impurity 1

D-(-)-ALPHA-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE

D-ALPHA-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE

D-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE

D-PHENYLGLYCINE-OME HCL

H-D-PHG-OME HCL

(R)-(-)-2-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE

Cephalexin Impurity 1 (D-Phenylglycine Methyl Ester)

(R)-(-)-2-Aminophenylacetic acid methyl ester hydrochloride

D-Phenylglycine methyl ester hydrochloride≥ 99% (HPLC)

D-Phenylglycine Methyl Ester Hydrochloride,99%e.e.

R-Phenyl Glycine methyl ester HCL

methyl (R)-aminophenylacetate hydrochloride

R-phenylglycine methyl ester hydrochloride

D-Phenylglycine Methyl Ester HCl

(r)-(-)-à-aminophenylacetic acid methyl ester hydrochloride

d-(-)-à-phenylglycine methyl ester hydrochloride

D-(-)-A-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE

D-Phenylglycine methyl ester hydrochlorid

(R)-(-)-2-phenylglycine methyl ester Hydrochloride ,98%

D-Phenylycine methyl ester hydrichloride

D-Phenylglycine methyl·hydrochloric acid

D-Phenylglycine methyl·hydrochloride

2-phenylglycine methyl ester hydrochloride

D-(-)-ɑ-Phenylglycine methyl ester hydrochloride, 96%

D-(-)-alpha-Phenylglycine methyl ester hydrochloride, 98+%

(R)-(-)-alpha-Aminophenylacetic acid Methyl Ester Hydrochloride

D(-)-ALPA-PHENYL GLYCINE METHYL ESTER HYDROCHLORIDE

methyl (2R)-2-amino-2-phenylacetate hydrochloride

(R)-(-)-2-Phenylglycine methyl ester HCI

D-ALPHA-PHENYLGLYCINE METHYLESTER HCL

Methyl (R)-2-Amino-2-Phenylacetate Hydrochloride

2-(2-aminophenyl)acetic acid methyl ester

H-D-Phg-OMe·HCl H-D-Phenylglycine methyl ester hydrochloride

Cephalexin Impurity 1 HCl (D-Phenylglycine Methyl Ester HCl)

Benzeneacetic acid, a-amino-, methyl ester, hydrochloride, (aR)-

D-ALPHA-Phenylglycine Methylester HCL / H-D-PHG-OME HCL

Cephalexin Impurity 1 HCl

H-D-Phg-OMe hydrochloride

(R)-(-)-2-Amino-2-phenylacetic Acid Methyl Ester Hydrochloride

H-D-PHG-OME HCL USP/EP/BP

(R)-()-2-Phenylglycine methyl ester hydrochlorideQ: What is (R)-()-2-Phenylglycine methyl ester hydrochloride Q: What is the CAS Number of (R)-()-2-Phenylglycine methyl ester hydrochloride

D-(-)-ALPHA-PHENYLGLYCINE METHYL ESTER HYD