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Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate

Product Name
Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate
CAS No.
680-15-9
Chemical Name
Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate
Synonyms
METHYL FLUOROSULFONYLDIFLUOROACETATE;METHYL DIFLUORO(FLUOROSULFONYL)ACETATE;2,2-DifL;METHYL FLUOROSULPHONYLDIFLUOROACETATE;METHYL 2-(FLUOROSULFONYL)DIFLUOROACETATE;uorosuL;FLUOROSULFONYL(DIFLUORO)ACETIC ACID METHYL ESTER;uoro-2-(fL;RSSYY(Iberdomide)-2;Methyldifluor(fluorsulfonyl)acetat
CBNumber
CB2685744
Molecular Formula
C3H3F3O4S
Formula Weight
192.11
MOL File
680-15-9.mol
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Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate Property

Boiling point:
117-118 °C(lit.)
Density 
1.509 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.351(lit.)
Flash point:
118 °F
storage temp. 
2-8°C(protect from light)
form 
liquid
Specific Gravity
1.52
color 
colorless to yellow
BRN 
1812896
InChI
InChI=1S/C3H3F3O4S/c1-10-2(7)3(4,5)11(6,8)9/h1H3
InChIKey
GQJCAQADCPTHKN-UHFFFAOYSA-N
SMILES
C(OC)(=O)C(F)(F)S(F)(=O)=O
CAS DataBase Reference
680-15-9(CAS DataBase Reference)
EPA Substance Registry System
Acetic acid, 2,2-difluoro-2-(fluorosulfonyl)-, methyl ester (680-15-9)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
10-34
Safety Statements 
26-36/37/39-45-16
RIDADR 
UN 2920 8/PG 2
WGK Germany 
3
10-21
Hazard Note 
Irritant
TSCA 
No
HazardClass 
3.2
PackingGroup 
III
HS Code 
29159000
Storage Class
3 - Flammable liquids
Hazard Classifications
Flam. Liq. 3
Skin Corr. 1B
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
390755
Product name
Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate
Purity
97%
Packaging
5g
Price
$38.3
Updated
2026/04/30
TCI Chemical
Product number
F0311
Product name
Methyl Difluoro(fluorosulfonyl)acetate
Purity
>97.0%(GC)
Packaging
5g
Price
$29
Updated
2026/04/30
TCI Chemical
Product number
F0311
Product name
Methyl Difluoro(fluorosulfonyl)acetate
Purity
>97.0%(GC)
Packaging
25g
Price
$95
Updated
2026/04/30
TRC
Product number
M301835
Product name
Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate
Packaging
1g
Price
$55
Updated
2021/12/16
Oakwood
Product number
006805
Product name
Methyl fluorosulfonyldifluoroacetate
Packaging
25g
Price
$30
Updated
2021/12/16
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Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

Efficient reagent for the trifluoromethylation of aryls and difluorocyclopropanation of alkenes.

Uses

Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate is a useful reagent for the trifluoromethylation of alkyl halides. It is also broadly applicable reagent for perfluoroalkylations for aryl iodides and bromides.

reaction suitability

reaction type: click chemistry

Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate Suppliers

Ningbo Fuhe Chemical Co., Ltd.
Tel
0574-1806900 18069001216
Email
nbfjj@126.com
Country
China
ProdList
99
Advantage
58
HANGZHOU HETE CHEMICAL TECHNOLOGY CO.,LTD
Tel
571-89189769 15168342188
Fax
0571-86205065
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China
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Yangzhou modier Electronic Materials Co., Ltd
Tel
13918702962 13761402923
Email
market@modeltemol.com
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China
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Shanghai F.R. Chemical Technology Co.,Ltd
Tel
021-52230662 13795399395
Email
seaman79@126.com
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China
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288
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SHANG FLUORO
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021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
399
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Shandong Ruihua Fluoride Industry Co., Ltd
Tel
530-6233885-001 05306238006
Email
ruihuafluoride@rhfuye.com
Country
China
ProdList
20
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58
Shanghai Jinghui Industrial Co., Ltd.
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021-60125035 18019281355
Email
vlchemjh@126.com
Country
China
ProdList
294
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Hubei Keji Biomedical Technology Co., Ltd.
Tel
13971512665 13971512665
Email
hbkjsw@foxmail.com
Country
China
ProdList
1000
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate manufacturers

R&D Scientific Inc.
Product
Methyl 2-(fluorosulfonyl)difluoroacetate 680-15-9
Price
US $890.00/Kg
Min. Order
0.100Kg
Purity
98
Supply Ability
5000 Kg
Release date
2025-04-29
Henan Aochuang Chemical Co.,Ltd.
Product
Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate 680-15-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09
Hebei Chuanghai Biotechnology Co., Ltd
Product
Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate 680-15-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2025-03-13

680-15-9, Methyl 2,2-difluoro-2-(fluorosulfonyl)acetateRelated Search:


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