ChemicalBook > CAS DataBase List > 6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE

6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE

Product Name
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
CAS No.
885275-59-2
Chemical Name
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
Synonyms
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE;Imidazo[1,2-a]pyridine, 6-chloro-3-iodo-;6-Chloro-3-iodoimidazo[1,2-a]pyridine,95%
CBNumber
CB2686549
Molecular Formula
C7H4ClIN2
Formula Weight
278.48
MOL File
885275-59-2.mol
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6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE Property

storage temp. 
2-8°C, protect from light
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
C381678
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridine
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
4222AC
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridine
Packaging
1g
Price
$211
Updated
2021/12/16
Matrix Scientific
Product number
070529
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridine
Purity
95%
Packaging
1g
Price
$794
Updated
2021/12/16
AK Scientific
Product number
4222AC
Product name
6-Chloro-3-iodoimidazo[1,2-a]pyridine
Packaging
10g
Price
$851
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0030405
Product name
IMIDAZO[1,2-A]PYRIDINE, 6-CHLORO-3-IODO-
Purity
95.00%
Packaging
1G
Price
$1450.68
Updated
2021/12/16
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6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE Chemical Properties,Usage,Production

Uses

It is used as an intermediate in organic syntheses

Synthesis

6188-25-6

885275-59-2

General procedure for the synthesis of 6-chloro-3-iodoimidazo[1,2-a]pyridine from 6-chloroimidazo[1,2-A]pyridine: To a solution of 6-chloroimidazo[1,2-A]pyridine (500.00 mg, 3.28 mmol) in N,N-dimethylformamide (DMF, 10 mL) at 0 °C was added N-iodosuccinimide (NIS, 884.70 mg, 3.94 mmol). The reaction mixture was slowly warmed to 20 °C and stirred continuously for 16 hours. Upon completion of the reaction, the reaction was quenched by the addition of saturated sodium bicarbonate solution (20 mL) and stirring was continued for 1 hour. The resulting solid product was collected by filtration and dried in an oven to afford the target compound 6-chloro-3-iodoimidazo[1,2-a]pyridine (900.00 mg, 3.23 mmol). The product was characterized by 1H NMR (400 MHz, CDCl3) with chemical shifts of δH 8.20 (s, 1H), 7.72 (s, 1H), 7.57 (d, 1H), 7.21 (dd, 1H).

References

[1] Patent: WO2018/98500, 2018, A1. Location in patent: Page/Page column 80; 81

6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE Suppliers

Alchem Pharmtech,Inc.
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Synthonix Inc
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Matrix Scientific
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Anichem LLC
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