2-Amino-3-bromo-5-chloropyridine

Uses

Product Name: 2-Amino-3-bromo-5-chloropyridine
CAS No.: 26163-03-1
Chemical Name: 2-Amino-3-bromo-5-chloropyridine
Synonyms: oro-2-pyridinamine;2-Amino-3-bromo-5-chlorop;3-Bromo-5-chloropyrid-2-ylamine;3-BROMO-5-CHLOROPYRIDIN-2-AMINE;3-BROMO-5-CHLORO-2-PYRIDINAMINE;2-AMINO-5-CHLORO-3-BROMOPYRIDINE;2-AMINO-3-BROMO-5-CHLOROPYRIDINE;2-Pyridinamine, 3-bromo-5-chloro-;2-Amino-3-bromo-5-chloropyridine98%;2-Amino-3-bromo-5-chloropyridine 98%
CBNumber: CB7495355
Molecular Formula: C5H4BrClN2
Formula Weight: 207.46
MOL File: 26163-03-1.mol

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2-Amino-3-bromo-5-chloropyridine Property

Melting point:: 82-83°C
Boiling point:: 256.2±35.0 °C(Predicted)
Density: 1.834±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Crystalline Powder
pka: 1.91±0.49(Predicted)
color: White to light brown
InChI: InChI=1S/C5H4BrClN2/c6-4-1-3(7)2-9-5(4)8/h1-2H,(H2,8,9)
InChIKey: UWGGGYYCKDCTGN-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Cl)C=C1Br
CAS DataBase Reference: 26163-03-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-41-37/38-22-21/22
Safety Statements: 26-36/37/39-39-36/37
RIDADR: UN2811
HazardClass: IRRITANT
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2402
Product name: 2-Amino-3-bromo-5-chloropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: A2402
Product name: 2-Amino-3-bromo-5-chloropyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $134
Updated: 2025/07/31

TRC

Product number: A602028
Product name: 2-Amino-3-bromo-5-chloropyridine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: E545
Product name: 2-Amino-3-bromo-5-chloropyridine
Packaging: 25g
Price: $22
Updated: 2021/12/16

Matrix Scientific

Product number: 044600
Product name: 3-Bromo-5-chloro-2-pyridinamine
Purity: >95%
Packaging: 25g
Price: $29
Updated: 2021/12/16

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2-Amino-3-bromo-5-chloropyridine Chemical Properties,Usage,Production

Uses

2-Amino-3-bromo-5-chloropyridine has a wide range of applications, including the synthesis of resins, surfactants, plastics, rubber, leather, papermaking, dyes, pharmaceuticals, pesticides, photographic film, explosives, building materials, and in disinfection, fumigation, and preservation processes. Furthermore, 2-amino-3-bromo-5-chloropyridine can be used as a basic organic chemical raw material and a high-quality fuel, primarily in the fields of fine chemicals and plastics.

Chemical Properties

Cream powder

Synthesis Reference(s)

Tetrahedron, 51, p. 8649, 1995 DOI: 10.1016/0040-4020(95)00478-Q

Synthesis

1072-98-6

26163-03-1

General procedure for the synthesis of 2-amino-3-bromo-5-chloropyridine from 2-amino-5-chloropyridine: In a 50L round bottom three-necked flask, a mixed solvent of DMF and ethanol (1:1.8 by volume, total 18.7L) was added, a thermometer and a reflux condenser were installed, and a magnetic stirrer was started. Sequentially, 4986.6 g of 2-amino-5-chloropyridine and 17336.3 g of N-bromosuccinimide were added, the temperature was raised to 85 °C and the reaction was stirred for 3.5 hours. The progress of the reaction was monitored by GC and TLC and after confirming the completion of the reaction, the solvent was removed using a rotary evaporator. The crude product obtained was recrystallized with hexane to give the pure 2-amino-3-bromo-5-chloropyridine. After drying, the calculated yield was 70.4% and purity was 99.15%.

References

[1] Patent: US2014/315888, 2014, A1. Location in patent: Paragraph 0620-0622
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 2949 - 2961
[3] Patent: US2009/156603, 2009, A1. Location in patent: Page/Page column 46
[4] Patent: EP1202994, 2004, B1. Location in patent: Page 18
[5] European Journal of Medicinal Chemistry, 2018, vol. 157, p. 115 - 126

2-Amino-3-bromo-5-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3-bromo-5-chloropyridine Suppliers

Americas 1 China 276 Europe 3 France 2 Germany 7 India 32 Japan 1 United Kingdom 16 United States 44 Global 382

Changzhou Yuxiang Chemical Co., Ltd

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Energy Chemical

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View Lastest Price from 2-Amino-3-bromo-5-chloropyridine manufacturers

Henan Fengda Chemical Co., Ltd

Product: 3-bromo-5-chloropyridin-2-amine 26163-03-1
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

Dideu Industries Group Limited

Product: 2-Amino-3-bromo-5-chloropyridine 26163-03-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-03

Career Henan Chemical Co

Product: 2-Amino-3-bromo-5-chloropyridine 26163-03-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%-100%
Supply Ability: 1
Release date: 2018-08-12

26163-03-1, 2-Amino-3-bromo-5-chloropyridineRelated Search:

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2-Amino-3-bromo-5-chloropyridine ISO 9001：2015 REACH

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26163-03-1

C5H4N2BrCl

C5H4N2BrF

Heterocycle-Pyridine series

amine | alkyl bromide| alkyl chloride

Amino-pyridine series

blocks

Bromides

Pyridines

Pyridine

Amines

Boronic Acid