Uses
ChemicalBook > CAS DataBase List > 2-Amino-3-bromo-5-chloropyridine

2-Amino-3-bromo-5-chloropyridine

Uses
Product Name
2-Amino-3-bromo-5-chloropyridine
CAS No.
26163-03-1
Chemical Name
2-Amino-3-bromo-5-chloropyridine
Synonyms
oro-2-pyridinamine;2-Amino-3-bromo-5-chlorop;3-Bromo-5-chloropyrid-2-ylamine;3-BROMO-5-CHLOROPYRIDIN-2-AMINE;3-BROMO-5-CHLORO-2-PYRIDINAMINE;2-AMINO-5-CHLORO-3-BROMOPYRIDINE;2-AMINO-3-BROMO-5-CHLOROPYRIDINE;2-Pyridinamine, 3-bromo-5-chloro-;2-Amino-3-bromo-5-chloropyridine98%;2-Amino-3-bromo-5-chloropyridine 98%
CBNumber
CB7495355
Molecular Formula
C5H4BrClN2
Formula Weight
207.46
MOL File
26163-03-1.mol
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2-Amino-3-bromo-5-chloropyridine Property

Melting point:
82-83°C
Boiling point:
256.2±35.0 °C(Predicted)
Density 
1.834±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Crystalline Powder
pka
1.91±0.49(Predicted)
color 
White to light brown
InChI
InChI=1S/C5H4BrClN2/c6-4-1-3(7)2-9-5(4)8/h1-2H,(H2,8,9)
InChIKey
UWGGGYYCKDCTGN-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Cl)C=C1Br
CAS DataBase Reference
26163-03-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22-21/22
Safety Statements 
26-36/37/39-39-36/37
RIDADR 
UN2811
HazardClass 
IRRITANT
PackingGroup 
III
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2402
Product name
2-Amino-3-bromo-5-chloropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$44
Updated
2025/07/31
TCI Chemical
Product number
A2402
Product name
2-Amino-3-bromo-5-chloropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$134
Updated
2025/07/31
TRC
Product number
A602028
Product name
2-Amino-3-bromo-5-chloropyridine
Packaging
100mg
Price
$45
Updated
2021/12/16
Oakwood
Product number
033564
Product name
2-Amino-3-bromo-5-chloropyridine
Purity
98%
Packaging
1g
Price
$9
Updated
2021/12/16
Oakwood
Product number
033564
Product name
2-Amino-3-bromo-5-chloropyridine
Purity
98%
Packaging
5g
Price
$10
Updated
2021/12/16
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2-Amino-3-bromo-5-chloropyridine Chemical Properties,Usage,Production

Uses

2-Amino-3-bromo-5-chloropyridine has a wide range of applications, including the synthesis of resins, surfactants, plastics, rubber, leather, papermaking, dyes, pharmaceuticals, pesticides, photographic film, explosives, building materials, and in disinfection, fumigation, and preservation processes. Furthermore, 2-amino-3-bromo-5-chloropyridine can be used as a basic organic chemical raw material and a high-quality fuel, primarily in the fields of fine chemicals and plastics.

Chemical Properties

Cream powder

Synthesis Reference(s)

Tetrahedron, 51, p. 8649, 1995 DOI: 10.1016/0040-4020(95)00478-Q

Synthesis

1072-98-6

26163-03-1

General procedure for the synthesis of 2-amino-3-bromo-5-chloropyridine from 2-amino-5-chloropyridine: In a 50L round bottom three-necked flask, a mixed solvent of DMF and ethanol (1:1.8 by volume, total 18.7L) was added, a thermometer and a reflux condenser were installed, and a magnetic stirrer was started. Sequentially, 4986.6 g of 2-amino-5-chloropyridine and 17336.3 g of N-bromosuccinimide were added, the temperature was raised to 85 °C and the reaction was stirred for 3.5 hours. The progress of the reaction was monitored by GC and TLC and after confirming the completion of the reaction, the solvent was removed using a rotary evaporator. The crude product obtained was recrystallized with hexane to give the pure 2-amino-3-bromo-5-chloropyridine. After drying, the calculated yield was 70.4% and purity was 99.15%.

References

[1] Patent: US2014/315888, 2014, A1. Location in patent: Paragraph 0620-0622
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 2949 - 2961
[3] Patent: US2009/156603, 2009, A1. Location in patent: Page/Page column 46
[4] Patent: EP1202994, 2004, B1. Location in patent: Page 18
[5] European Journal of Medicinal Chemistry, 2018, vol. 157, p. 115 - 126

2-Amino-3-bromo-5-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-3-bromo-5-chloropyridine manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-bromo-5-chloropyridin-2-amine 26163-03-1
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Dideu Industries Group Limited
Product
2-Amino-3-bromo-5-chloropyridine 26163-03-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-03
Career Henan Chemical Co
Product
2-Amino-3-bromo-5-chloropyridine 26163-03-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-100%
Supply Ability
1
Release date
2018-08-12

26163-03-1, 2-Amino-3-bromo-5-chloropyridineRelated Search:


  • 2-AMINO-3-BROMO-5-CHLOROPYRIDINE
  • 3-BROMO-5-CHLORO-2-PYRIDINAMINE
  • 3-BROMO-5-CHLOROPYRIDIN-2-AMINE
  • 2-AMINO-5-CHLORO-3-BROMOPYRIDINE
  • 2-Amino-3-bromo-5-chloropyridine 98%
  • 3-Bromo-5-chloropyrid-2-ylamine
  • 2- aMino-3-broMo -5-chlorine pyridine
  • 3-BroMo-5-chloro-2-pyridinaMine, >95%
  • 2-Amino-3-bromo-5-chloropyridine98%
  • 2-Amino-3-bromo-5-chloropyridine &gt
  • oro-2-pyridinamine
  • 2-Pyridinamine, 3-bromo-5-chloro-
  • 2-Amino-3-bromo-5-chloropyridine ISO 9001:2015 REACH
  • 2-Amino-3-bromo-5-chlorop
  • 26163-03-1
  • C5H4N2BrCl
  • C5H4N2BrF
  • Heterocycle-Pyridine series
  • amine | alkyl bromide| alkyl chloride
  • Amino-pyridine series
  • blocks
  • Bromides
  • Pyridines
  • Pyridine
  • Amines
  • Boronic Acid