2-Amino-3-bromo-5-chloropyridine
Uses- Product Name
- 2-Amino-3-bromo-5-chloropyridine
- CAS No.
- 26163-03-1
- Chemical Name
- 2-Amino-3-bromo-5-chloropyridine
- Synonyms
- oro-2-pyridinamine;2-Amino-3-bromo-5-chlorop;3-Bromo-5-chloropyrid-2-ylamine;3-BROMO-5-CHLOROPYRIDIN-2-AMINE;3-BROMO-5-CHLORO-2-PYRIDINAMINE;2-AMINO-5-CHLORO-3-BROMOPYRIDINE;2-AMINO-3-BROMO-5-CHLOROPYRIDINE;2-Pyridinamine, 3-bromo-5-chloro-;2-Amino-3-bromo-5-chloropyridine98%;2-Amino-3-bromo-5-chloropyridine 98%
- CBNumber
- CB7495355
- Molecular Formula
- C5H4BrClN2
- Formula Weight
- 207.46
- MOL File
- 26163-03-1.mol
2-Amino-3-bromo-5-chloropyridine Property
- Melting point:
- 82-83°C
- Boiling point:
- 256.2±35.0 °C(Predicted)
- Density
- 1.834±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Crystalline Powder
- pka
- 1.91±0.49(Predicted)
- color
- White to light brown
- InChI
- InChI=1S/C5H4BrClN2/c6-4-1-3(7)2-9-5(4)8/h1-2H,(H2,8,9)
- InChIKey
- UWGGGYYCKDCTGN-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(Cl)C=C1Br
- CAS DataBase Reference
- 26163-03-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-41-37/38-22-21/22
- Safety Statements
- 26-36/37/39-39-36/37
- RIDADR
- UN2811
- HazardClass
- IRRITANT
- PackingGroup
- III
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A2402
- Product name
- 2-Amino-3-bromo-5-chloropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- A2402
- Product name
- 2-Amino-3-bromo-5-chloropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $134
- Updated
- 2025/07/31
- Product number
- A602028
- Product name
- 2-Amino-3-bromo-5-chloropyridine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 033564
- Product name
- 2-Amino-3-bromo-5-chloropyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $9
- Updated
- 2021/12/16
- Product number
- 033564
- Product name
- 2-Amino-3-bromo-5-chloropyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
2-Amino-3-bromo-5-chloropyridine Chemical Properties,Usage,Production
Uses
2-Amino-3-bromo-5-chloropyridine has a wide range of applications, including the synthesis of resins, surfactants, plastics, rubber, leather, papermaking, dyes, pharmaceuticals, pesticides, photographic film, explosives, building materials, and in disinfection, fumigation, and preservation processes. Furthermore, 2-amino-3-bromo-5-chloropyridine can be used as a basic organic chemical raw material and a high-quality fuel, primarily in the fields of fine chemicals and plastics.
Chemical Properties
Cream powder
Synthesis Reference(s)
Tetrahedron, 51, p. 8649, 1995 DOI: 10.1016/0040-4020(95)00478-Q
Synthesis
1072-98-6
26163-03-1
General procedure for the synthesis of 2-amino-3-bromo-5-chloropyridine from 2-amino-5-chloropyridine: In a 50L round bottom three-necked flask, a mixed solvent of DMF and ethanol (1:1.8 by volume, total 18.7L) was added, a thermometer and a reflux condenser were installed, and a magnetic stirrer was started. Sequentially, 4986.6 g of 2-amino-5-chloropyridine and 17336.3 g of N-bromosuccinimide were added, the temperature was raised to 85 °C and the reaction was stirred for 3.5 hours. The progress of the reaction was monitored by GC and TLC and after confirming the completion of the reaction, the solvent was removed using a rotary evaporator. The crude product obtained was recrystallized with hexane to give the pure 2-amino-3-bromo-5-chloropyridine. After drying, the calculated yield was 70.4% and purity was 99.15%.
References
[1] Patent: US2014/315888, 2014, A1. Location in patent: Paragraph 0620-0622
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 2949 - 2961
[3] Patent: US2009/156603, 2009, A1. Location in patent: Page/Page column 46
[4] Patent: EP1202994, 2004, B1. Location in patent: Page 18
[5] European Journal of Medicinal Chemistry, 2018, vol. 157, p. 115 - 126
2-Amino-3-bromo-5-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-3-bromo-5-chloropyridine Suppliers
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View Lastest Price from 2-Amino-3-bromo-5-chloropyridine manufacturers
- Product
- 3-bromo-5-chloropyridin-2-amine 26163-03-1
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 2-Amino-3-bromo-5-chloropyridine 26163-03-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-03
- Product
- 2-Amino-3-bromo-5-chloropyridine 26163-03-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-100%
- Supply Ability
- 1
- Release date
- 2018-08-12