ISOBUTYLAMINE HYDROCHLORIDE
Uses- Product Name
- ISOBUTYLAMINE HYDROCHLORIDE
- CAS No.
- 5041-09-8
- Chemical Name
- ISOBUTYLAMINE HYDROCHLORIDE
- Synonyms
- i-BACl;isobutylamineHCl;ISOBUTYLAMMONIUM CHLORIDE;ISOBUTYLAMINE HYDROCHLORIDE;IsobutylamineHydrochloride>2-methylpropylazanium chloride;2-Methylpropan-1-amine hydrochloride;2-Methyl-1-propanamine hydrochloride;1-AMINO-2-METHYLPROPANE HYDROCHLORIDE;1-Propanamine,2-methyl-, hydrochloride (9CI)
- CBNumber
- CB2687278
- Molecular Formula
- C4H12ClN
- Formula Weight
- 109.6
- MOL File
- 5041-09-8.mol
ISOBUTYLAMINE HYDROCHLORIDE Property
- Melting point:
- 176.0 to 180.0 °C
- storage temp.
- Inert atmosphere,Room Temperature
- Water Solubility
- almost transparency in Water
- form
- powder to crystal
- color
- White to Almost white
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-41-37/38-22
- Safety Statements
- 26-36/37/39-39
- HS Code
- 2921199990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- I0096
- Product name
- Isobutylamine Hydrochloride
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $47
- Updated
- 2025/07/31
- Product number
- I0096
- Product name
- Isobutylamine Hydrochloride
- Purity
- >99.0%(T)
- Packaging
- 500g
- Price
- $386
- Updated
- 2025/07/31
- Product number
- M322118
- Product name
- 2-Methylpropan-1-amineHydrochloride
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M322118
- Product name
- 2-Methylpropan-1-amineHydrochloride
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 8085AL
- Product name
- Isobutylamine Hydrochloride
- Packaging
- 25g
- Price
- $110
- Updated
- 2021/12/16
ISOBUTYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Isobutylamine hydrochloride is an organic amine hydrochloride, and it has been reported in the literature that it can be used to prepare methyl 3-(2-amino-2-thioethyl)benzoate. Methyl 3-(2-amino-2-thioethyl)benzoate is an important fine chemical raw material and pharmaceutical intermediate. It is a key intermediate for the preparation of a novel phosphate transport inhibitor, 2-[[3-[[4-(2-hydroxyethyl)-2-thiazolyl]methyl]benzoyl]amino]-5-(1-piperidinyl)-,(2E)-2-[[4-chloro-3-(trifluoromethyl)phenyl]methylene]benzoylhydrazine.
Synthesis
72-18-4
5041-09-8
The general procedure for the synthesis of isobutylamine hydrochloride from L-valine is as follows: a magnetic stirring bar, 3 mL of n-propanol (n-PrOH), 10 mmol of R-carvone and 5 mmol of L-valine were added to a pressure vessel. The vessel was heated from room temperature to 190 °C in 5 min under stirring conditions. If the reaction mixture was slurry-like, it was continued at 190°C until the solution became clear. After the vessel was cooled below the boiling point of the solvent, it was carefully vented to release the generated CO2. Subsequently, 10 mL of 2M hydrochloric acid (HCl) was added to the vessel and the vessel was again heated to 190 °C in 5 min under stirring and then cooled. The aqueous reaction mixture was washed three times with 25 mL of ether and the aqueous solvent was removed by distillation to give the hydrochloride product. The hydrochloride was transferred to a vacuum oven and dried overnight at 150 °C and 10 Torr pressure. Finally, the hydrochloride product was weighed and analyzed by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR).The NMR data of 2-methylpropan-1-amine hydrochloride were as follows: δH 0.83 (6H, d, J = 4 Hz), 1.79 (1H, m, J = 8 Hz), 2.69 (2H, d, J = 8 Hz); δC 18.8, 26.2, 46.3.
References
[1] Patent: US2014/275569, 2014, A1. Location in patent: Page/Page column 0045; 0048; 0066; 0067
ISOBUTYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ISOBUTYLAMINE HYDROCHLORIDE manufacturers
- Product
- ISOBUTYLAMINE HYDROCHLORIDE 5041-09-8
- Price
- US $80.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-07-25