Tioxolone
- Product Name
- Tioxolone
- CAS No.
- 4991-65-5
- Chemical Name
- Tioxolone
- Synonyms
- 6-HYDROXY-1,3-BENZOXATHIOL-2-ONE;Trocinate;ol110;Camyna;Stepin;Acnosan;Thiphen;tioxolon;thidoxol;ioxolone
- CBNumber
- CB2696092
- Molecular Formula
- C7H4O3S
- Formula Weight
- 168.17
- MOL File
- 4991-65-5.mol
Tioxolone Property
- Melting point:
- 158-160 °C(lit.)
- Boiling point:
- 267.1°C (rough estimate)
- Density
- 1.4844 (rough estimate)
- refractive index
- 1.5151 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- 95% ethanol: soluble50mg/mL, clear to very slightly hazy, colorless to yellow
- form
- A solid
- pka
- 8.14±0.20(Predicted)
- Merck
- 9456
- LogP
- 1.770 (est)
- CAS DataBase Reference
- 4991-65-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Tioxolone(4991-65-5)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- DM2953750
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 217077
- Product name
- 6-Hydroxy-1,3-benzoxathiol-2-one
- Purity
- ≥98%
- Packaging
- 50g
- Price
- $166.2
- Updated
- 2024/03/01
- Product number
- OR937717
- Product name
- 6-Hydroxy-1,3-benzoxathiol-2-one
- Purity
- 95%
- Packaging
- 25g
- Price
- $261
- Updated
- 2021/12/16
- Product number
- 38111
- Product name
- 6-Hydroxybenzo[d][1,3]oxathiol-2-one
- Purity
- 95+%
- Packaging
- 10g
- Price
- $350
- Updated
- 2021/12/16
- Product number
- V1364
- Product name
- Tioxolone
- Packaging
- 25g
- Price
- $852
- Updated
- 2021/12/16
- Product number
- CHM0013052
- Product name
- 6-HYDROXY-1,3-BENZOXATHIOL-2-ONE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1270.5
- Updated
- 2021/12/16
Tioxolone Chemical Properties,Usage,Production
Chemical Properties
light yellow to beige powder
Originator
Acnosan,Unia
Uses
6-Hydroxy-1,3-benzoxathiol-2-one was used in the synthesis of heterocycle-phosphor esters having potential antimicrobial activity.
Uses
antiseborrhoic
Definition
ChEBI: A 1,3-benzoxathiole having a hydroxy substituent at the 6-position.
Manufacturing Process
40 g potassium thiocyanate in 50 ml of water are added, while stirring at
room temperature, to a solution of 11 g of resorcinol and 50 g of crystallized
copper sulfate in 250 ml of water. The black cupric thiocyanate formed
becomes colorless after a short time, which indicates that the introduction of
thiocyanogen is terminated. The cuprous thiocyanate is removed by filtering
with suction and then washed with water; the filtrate is mixed with 50 ml of a
2 N sodium carbonate solution, whereby the imino-thiocarbonate of resorcinol
separates in the form of a colorless crystalline body. The yield amounts to 16
g. The new compound which melts at 149°C dissolves very easily in many
organic solvents and in mineral acids.
A 10% solution of the imino-thiocarbonate of resorcinol in 10% hydrochloric
acid is heated for 15 min on the steam bath. The 6-hydroxy-1,3-benzoxathiol-
2-one (thiocarbonate free from) nitrogen separates, on cooling, in the form of
fine crystals melting at 158°C.
Therapeutic Function
Antiseborreic, Antifungal, Keratolytic
General Description
Antimicrobial and cytostatic properties of 6-hydroxy-1,3-benzoxathiol-2-one has been investigated. Supramolecular structure of 6-hydroxy-1,3-benzoxathiol-2-one has been studied.
Tioxolone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Tioxolone manufacturers
- Product
- Tioxolone 4991-65-5
- Price
- US $1.00/IU
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-12-27