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PHORBOL 12,13-DIACETATE

Product Name
PHORBOL 12,13-DIACETATE
CAS No.
24928-15-2
Chemical Name
PHORBOL 12,13-DIACETATE
Synonyms
PDA;PHORBOL-DIACETATE;phorbol11,12-diacetate;phorbol10,11-diacetate;PHORBOL 12,13-DIACETATE;Phorbol 12,13-Diacetate >99%;PHORBOL 12,13-DIACETATE, 4BETA;l)-1,1,6,8-alpha-tetramethyl-,9,9a-diacetate,(+);8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethy;5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,16-beta,4,4a,7a-alpha,7b,
CBNumber
CB2702142
Molecular Formula
C24H32O8
Formula Weight
448.51
MOL File
24928-15-2.mol
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PHORBOL 12,13-DIACETATE Property

Boiling point:
477.23°C (rough estimate)
Density 
1.1793 (rough estimate)
refractive index 
1.4480 (estimate)
storage temp. 
−20°C
solubility 
H2O: soluble
form 
powder
color 
white
BRN 
2317312
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28-36/37/38
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
GZ0651000
F 
8-10
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
2915290000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AHH
Product number
MT-21404
Product name
Phorbol 12,13-diacetate
Purity
95%
Packaging
0.01g
Price
$298
Updated
2021/12/16
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PHORBOL 12,13-DIACETATE Chemical Properties,Usage,Production

Uses

Phorbol 12,13-diacetate may be used to stimulate protein kinase C (PKC) for phosphorylation of retinal proteins.

General Description

Phorbol ester with enhanced hydrophilicity.

Biochem/physiol Actions

Phorbol 12,13-diacetate (PDA) serves as a protein kinase C (PKC). It induces arrest in translocation in rod photoreceptors. PDA facilitates PKC in regulating airway contractility by inducing transient relaxation after a sustained contraction of the human isolated bronchus. PDA improves the synaptic transmission of nociceptive parabrachioamygdaloid (PBA) input onto neurons of the capsular central amygdaloid (CeAC) nucleus via activating PKC and extracellular-regulated kinase (ERK).

PHORBOL 12,13-DIACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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PHORBOL 12,13-DIACETATE Suppliers

China 8 Germany 1 Japan 1 South Korea 1 Switzerland 2 United Kingdom 1 United States 5 Global 19
SIGMA-RBI
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Switzerland
ProdList
6896
Advantage
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Alexis Corporation
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alexis-ch@alexis-corp.ch
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Switzerland
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24928-15-2, PHORBOL 12,13-DIACETATERelated Search:

PHORBOL 12-MYRISTATE 13-ACETATE ortho-phenylenediamine(o-pda POTATO DEXTROSE AGAR (PDA) 1,4-Di(acryloyl)piperazine, N,Nμ-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide,PDA,PDA, 1,4-Bis(acryloyl)piperazine meta-phenylenediamine(m-pda para-phenylenediamine(p-pda 2-N-p-PDA 4-n-o-pd 1-PYRENEDECANOIC ACID (PDA) PHORBOL PHORBOL 12,13-DIACETATE PDDHV PHORBOL 12,13,20-TRIACETATE, 4BETA PHORBOL 12,13-DIDECANOATE PHORBOL 12,13-DIBUTYRATE 3H-PMA PDNHV PHORBOL 12-N-METHYLANTHRANILATE

  • Phorbol 12,13-Diacetate >99%
  • (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl diacetate
  • PHORBOL 12,13-DIACETATE
  • PHORBOL 12,13-DIACETATE, 4BETA
  • PDA
  • 5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,16-beta,4,4a,7a-alpha,7b,
  • 8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethy
  • l)-1,1,6,8-alpha-tetramethyl-,9,9a-diacetate,(+)
  • phorbol10,11-diacetate
  • phorbol11,12-diacetate
  • PHORBOL-DIACETATE
  • (1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-5-oxo-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulene-4aβ,7bα,9β,9aα-tetrol 9,9a-diacetate
  • 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9,9a-bis(acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-
  • 24928-15-2
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Kinase/Phosphatase Biology
  • Protein Kinase C (PKC)
  • Serine/Threonine Kinase Activators
  • Activator