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AC-ESMD-CHO

Product Name
AC-ESMD-CHO
CAS No.
191338-87-1
Chemical Name
AC-ESMD-CHO
Synonyms
AC-ESMD-CHO;AC-ESMD-ALDEHYDE;AC-GLU-SER-MET-ASP-CHO;N-Acetyl-Glu-Ser-Met-Asp-al;AC-GLU-SER-MET-ASP-ALDEHYDE;ACETYL-GLU-SER-MET-ASPARTINAL;N-ACETYL-GLU-SER-MET-ASPARTINAL;GRANZYME B INHIBITOR (ALDEHYDE);AC-GLU-SER-MET-ASP-ALDEHYDE (PSEUDO ACID);Acetyl-glutamyl-serinyl-methionyl-aspartal
CBNumber
CB2729839
Molecular Formula
C19H30N4O10S
Formula Weight
506.53
MOL File
191338-87-1.mol
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AC-ESMD-CHO Property

Boiling point:
1049.7±65.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 1 mg/mL
pka
4.19±0.10(Predicted)
form 
powder
color 
white
Sequence
Ac-Glu-Ser-Met-Asp-CHO
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FA111075
Product name
Ac-Glu-Ser-Met-Asp-aldehyde (pseudo acid)
Packaging
2mg
Price
$132
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111075
Product name
Ac-Glu-Ser-Met-Asp-aldehyde (pseudo acid)
Packaging
5mg
Price
$263
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111075
Product name
Ac-Glu-Ser-Met-Asp-aldehyde (pseudo acid)
Packaging
10mg
Price
$457
Updated
2021/12/16
Chem-Impex
Product number
07693
Product name
Ac-Glu-Ser-Met-Asp-aldehyde(pseudoacid)
Packaging
25MG
Price
$672.09
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004281
Product name
N-ACETYL-GLU-SER-MET-ASP-AL
Purity
95.00%
Packaging
1MG
Price
$740.39
Updated
2021/12/16
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AC-ESMD-CHO Chemical Properties,Usage,Production

Uses

Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site[1][2].

References

[1] Hayashida M, et al. Cell death induction by CTL: perforin/granzyme B system dominantly acts for cell death induction in human hepatocellular carcinoma cells. Proc Soc Exp Biol Med. 2000 Nov;225(2):143-50. DOI:10.1046/j.1525-1373.2000.22518.x
[2] Agniswamy J, et al. Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. FEBS J. 2007 Sep;274(18):4752-65. DOI:10.1111/j.1742-4658.2007.05994.x

AC-ESMD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-ESMD-CHO Suppliers

China 38 Switzerland 2 United Kingdom 3 United States 8 Global 51
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74
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View Lastest Price from AC-ESMD-CHO manufacturers

Career Henan Chemica Co
Product
AC-ESMD-CHO 191338-87-1
Price
US $1.80/KG
Min. Order
1g
Purity
96%-99%
Supply Ability
1kg/10kg/100kg
Release date
2020-11-08

191338-87-1, AC-ESMD-CHORelated Search:

AC-WEHD-CHO AC-YVAD-CHO AC-WEHD-AMC AC-LYS(AC)-D-ALA-D-ALA-OH AC-DEVD-CHO AC-DMQD-CHO Ac-DEVD-CMK AC-GLU-SER-MET-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN AC-ESMD-CHO

  • AC-ESMD-ALDEHYDE
  • AC-ESMD-CHO
  • ACETYL-GLU-SER-MET-ASPARTINAL
  • AC-GLU-SER-MET-ASP-ALDEHYDE
  • AC-GLU-SER-MET-ASP-ALDEHYDE (PSEUDO ACID)
  • AC-GLU-SER-MET-ASP-CHO
  • N-Acetyl-Glu-Ser-Met-Asp-al
  • Acetyl-glutamyl-serinyl-methionyl-aspartal
  • N-ACETYL-GLU-SER-MET-ASPARTINAL
  • CASPASE-3 PROCESSING ENZYME INHIBITOR II (ALDEHYDE)
  • CASPASE-3 PROCESSING INHIBITOR II (ALDEHYDE)
  • GRANZYME B INHIBITOR (ALDEHYDE)
  • L-Methioninamide, N-acetyl-L-α-glutamyl-L-seryl-N-[(1S)-2-carboxy-1-formylethyl]-
  • 191338-87-1
  • C19H30N4O10S
  • Inhibitors
  • Cell Signaling and Neuroscience
  • Caspases
  • Caspase 3
  • Cell Biology
  • BioChemical
  • Apoptosis and Cell Cycle
  • Pepetides
  • peptides