RIFAMYCIN SV

Product Name: RIFAMYCIN SV
CAS No.: 6998-60-3
Chemical Name: RIFAMYCIN SV
Synonyms: rifocyn;rifocin;rifamicinesv;RIFAMYCIN SV;RIFAMYCIN INN;Rifamycin S-Na;Rifamycin (9CI);RIFAMYCIN SV USP/EP/BP;Rifaximin EP Impurity C;Rifaximin impurity C (EP)
CBNumber: CB2731058
Molecular Formula: C37H47NO12
Formula Weight: 697.77
MOL File: 6998-60-3.mol

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RIFAMYCIN SV Property

Melting point:: 300° (dec 140°)
alpha: D20 -4° (methanol)
Boiling point:: 701.9°C (rough estimate)
Density: 1.2275 (rough estimate)
refractive index: 1.5350 (estimate)
pka: 5.17±0.70(Predicted)

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Safety

Toxicity: LD50 in mice (mg/kg): 550 i.v.; 625 i.p.; 2120 orally (Bergamini, Fowst)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: R509625
Product name: Rifogal
Packaging: 50mg
Price: $95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0013235
Product name: RIFAMYCIN SV
Purity: 95.00%
Packaging: 5MG
Price: $497.32
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0013235
Product name: RIFAMYCIN SV
Purity: 95.00%
Packaging: 100MG
Price: $4960
Updated: 2021/12/16

AvaChem

Product number: 2841A
Product name: Rifamycin SV
Packaging: 10g
Price: $189
Updated: 2021/12/16

AvaChem

Product number: 2841A
Product name: Rifamycin SV
Packaging: 100mg
Price: $40
Updated: 2021/12/16

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RIFAMYCIN SV Chemical Properties,Usage,Production

Uses

Rifogal (Rifaximin EP Impurity C NA) is a antibacterial drug which functions by inhibiting bacterial RNA polymerase (RNAP), is an important part of the antibacteral armamentarium. Also, it is one of the few drugs in a multidrug regimens for treating lung disease (LD) due to Mycobacterium avium complex (MAC).

Definition

ChEBI: A member of the class of rifamycins that exhibits antibiotic and antitubercular properties.

Pharmaceutical Applications

The simplest rifamycin in clinical use, obtained by elimination of a glycolic moiety from rifamycin B. Formulated as sodium salt for parenteral administration. Also available for topical use. Its activity, general properties and pharmacokinetics are very similar to those of rifamide. It is orally absorbed and excreted mainly in the bile. Intramuscular doses of 250 mg produce mean plasma levels of about 2 mg/L. The plasma half-life is around 2 h.
In addition to uses similar to those of rifamide, it is administered topically in surgery and has been proposed for the treatment of synovitis by intra-articular injections. A topical preparation is used for application to wounds and bedsores. Cases of anaphylactic reactions have been reported after local administration of the drug.

Purification Methods

Rifamycin SV gives yellow-orange crystals from Et2O/pet ether or aqueous EtOH, is very soluble in MeOH, EtOH, Me2CO and EtOAc, and is less soluble in Et2O and HCO3-, but slightly soluble in H2O and pet ether. Its UV has max at 223, 314 and 445nm ( 1cm 586, 322 and 204) in phosphatebuffer pH 7. [NMR: Bergamini & Fowst Arzneim.-Forsch 15 951 1965.]

RIFAMYCIN SV Preparation Products And Raw materials

Raw materials

Preparation Products

Rifamycin Sodium

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RIFAMYCIN SV Suppliers

China 81 India 4 United Kingdom 2 United States 10 Global 97

Raw material medicin reagent co.,Ltd

Tel: 025-57798860
Email: sales@njromanme.com
Country: China
ProdList: 4534
Advantage: 58

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

3B Scientific (Wuhan) Corporation Limited

Tel: 0086-27-88063677 18186135292
Fax: 027-88063656
Email: sales@3bsc.com
Country: China
ProdList: 293
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Hubei widely chemical technology Co., Ltd.

Tel: 027-59402396 13419635609
Fax: 027-83989310
Email: 13419635609@163.com
Country: China
ProdList: 1993
Advantage: 55

Wuhan Wsem Biological Co., Ltd.

Tel: 027-83778876 13667159345
Fax: 027-83778876
Email: 13667159345@163.com
Country: China
ProdList: 1940
Advantage: 55

Wellman Pharmaceutical Group Limited

Tel: 027-027-83778875 15807197853
Fax: 027-83991220
Email: 15807197853@163.com
Country: China
ProdList: 3978
Advantage: 58

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View Lastest Price from RIFAMYCIN SV manufacturers

Hebei Duling International Trade Co. LTD

Product: RIFAMYCIN SV 6998-60-3
Price: US $17.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-01-06

Shaanxi Dideu Medichem Co. Ltd

Product: RIFAMYCIN SV 6998-60-3
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-05-07

Hebei Zhanyao Biotechnology Co. Ltd

Product: RIFAMYCIN 6998-60-3
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-18

6998-60-3, RIFAMYCIN SVRelated Search:

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RIFAMYCIN SV

17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-21-acetate

rifamicinesv

rifocin

rifocyn

Rifamycin S-Na

Rifaximin EP Impurity C

19,21,25(29),26-octaen-13-yl acetate

Rifaximin impurity C (EP)

Rifaximin Impurity 3 (Rifaximin EP Impurity C)

Rifampicin Impurit Ⅱ:rifamycin SV

Rifaximin EP Impurity C (Rifamycin SV)

Rifamycin (9CI)

RIFAMYCIN SV USP/EP/BP

(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-(Acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione

RifamycinQ: What is Rifamycin Q: What is the CAS Number of Rifamycin Q: What is the storage condition of Rifamycin Q: What are the applications of Rifamycin

RIFAMYCIN INN

Rifampicin Impurit Ⅱ:rifamycin SV

Rifaximin EP Impurity C (Rifamycin)

6998-60-3

C37H47NO12