3-CYANO-7-ETHOXYCOUMARIN

Product Name: 3-CYANO-7-ETHOXYCOUMARIN
CAS No.: 117620-77-6
Chemical Name: 3-CYANO-7-ETHOXYCOUMARIN
Synonyms: 3-CETC;CAS:117620-77-6;3-CYANO-7-ETHOXYCOUMARIN;CEC [3-Cyano-7-ethoxycoumarin;7-ETHOXYCOUMARIN-3-CARBONITRILE;7-ethoxy-2-oxochromene-3-carbonitrile;3-Cyano-7-ethoxycoumarin, 10 mM in DMSO;7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile;3-CYANO-7-ETHOXYCOUMARIN ISO 9001：2015 REACH;7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
CBNumber: CB2732282
Molecular Formula: C12H9NO3
Formula Weight: 215.2
MOL File: 117620-77-6.mol

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3-CYANO-7-ETHOXYCOUMARIN Property

Melting point:: 210-212°C
Boiling point:: 396.8±42.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble
form: Solid
color: yellow to orange
λmax: 356 nm (Buffer pH7); 355 nm(MeOH)
Biological Applications: As a substrate for measuring cytochrome P450 enzymes activity; cytochrome P450 inhibition assays; drug design; drug metabolism; treating viral or parasite infections.
InChI: InChI=1S/C12H9NO3/c1-2-15-10-4-3-8-5-9(7-13)12(14)16-11(8)6-10/h3-6H,2H2,1H3
InChIKey: YAFGHMIAFYQSCF-UHFFFAOYSA-N
SMILES: C1(=O)OC2=CC(OCC)=CC=C2C=C1C#N

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: UC455
Product name: 3-Cyano-7-ethoxycoumarin
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $279
Updated: 2023/06/20

Sigma-Aldrich

Product number: UC455
Product name: 3-Cyano-7-ethoxycoumarin
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $509
Updated: 2023/06/20

Cayman Chemical

Product number: 25441
Product name: 3-Cyano-7-ethoxycoumarin
Purity: ≥95%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 25441
Product name: 3-Cyano-7-ethoxycoumarin
Purity: ≥95%
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 25441
Product name: 3-Cyano-7-ethoxycoumarin
Purity: ≥95%
Packaging: 25mg
Price: $193
Updated: 2024/03/01

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3-CYANO-7-ETHOXYCOUMARIN Chemical Properties,Usage,Production

Uses

Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.

Uses

3-Cyano-7-ethoxycoumarin has been used as a substrate in cytochrome P (CYP) inhibition for fluorescence measurement.

General Description

3-Cyano-7-ethoxycoumarin is a fluorescent substrate for Cytochrome P450 1A1 (CYP1A1), Cytochrome P450 1A2 (CYP1A2), Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19).

Biochem/physiol Actions

Fluorescent probe useful in microsomal dealkylase studies. Typical drug-drug interactions resulting from enzyme inhibition.

3-CYANO-7-ETHOXYCOUMARIN Preparation Products And Raw materials

Raw materials

Malononitrile 4-Ethoxyphenol Chloroform Hydrochloric acid Sodium bicarbonate Methanol Sodium hydroxide

Preparation Products

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3-CYANO-7-ETHOXYCOUMARIN Suppliers

China 140 Europe 1 Germany 2 India 3 Switzerland 2 United Kingdom 4 United States 24 Global 176

Absin Bioscience Inc.

Tel: 021-38015121 18438616290
Email: lanwu@univ-bio.com
Country: China
ProdList: 24731
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1876
Advantage: 55

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Synchem OHG

Tel: +49 5662 408730
Fax: +49 5662 4087320
Email: info@synchem.de
Country: Germany
ProdList: 4705
Advantage: 70

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View Lastest Price from 3-CYANO-7-ETHOXYCOUMARIN manufacturers

Dideu Industries Group Limited

Product: 3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-01

Career Henan Chemical Co

Product: 3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-09

Career Henan Chemical Co

Product: 3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 1ton
Release date: 2019-07-09

117620-77-6, 3-CYANO-7-ETHOXYCOUMARINRelated Search:

CoumarinDerivatives Coumarin-3-carboxylic acid Sodium cyanoborohydride 7-Ethoxycoumarin 3-(3-methoxyphenoxy)propanenitrile 7-METHOXY-2H-CHROMENE-3-CARBONITRILE 3-Cyano-7-hydroxycoumarin 4-METHOXYCINNAMONITRILE 3-CYANOCOUMARIN 2H-CHROMENE-3-CARBONITRILE 3-CYANO-7-ETHOXYCOUMARIN

7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile

7-ETHOXYCOUMARIN-3-CARBONITRILE

3-CYANO-7-ETHOXYCOUMARIN

2H-1-Benzopyran-3-carbonitrile,7-ethoxy-2-oxo-(9CI)

7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile

3-Cyano-7-ethoxycoumarin [7-Ethoxycoumarin-3-carbonitrile] *Cytochrome P450 Substrate*

CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6*

CEC [3-Cyano-7-ethoxycoumarin

2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-

3-CYANO-7-ETHOXYCOUMARIN ISO 9001：2015 REACH

3-CETC

3-Cyano-7-ethoxycoumarin, Fluorogenic cytochrome P450 monooxygenase substrate

3-Cyano-7-ethoxycoumarin, 10 mM in DMSO

CAS:117620-77-6

7-ethoxy-2-oxochromene-3-carbonitrile

117620-77-6

11620-77-6

BioChemical

Biochemicals and Reagents

Luminescent Compounds/Detection

Other luminescent compounds

ETHOXY

Coumarins

Detection and Quantitation

Reagents

Multi-Drug Resistance and Drug Metabolism

Drug and Xenobiotic Metabolism

Substrates, Inducers, Inhibitors