3-Cyano-7-hydroxycoumarin

Product Name: 3-Cyano-7-hydroxycoumarin
CAS No.: 19088-73-4
Chemical Name: 3-Cyano-7-hydroxycoumarin
Synonyms: 3-CYANOUMBELLIFERONE;3-Cyanoumbelliferone>3-CYANO-7-HYDROXYCOUMARIN;3-Cyano-7-hydroxycoumarin 95+%;7-Hydroxy-2-oxochromene-3-carbonitrile;3-CYANOUMBELLIFERONE, FOR FLUORESCENCE*;7-hydroxy-2-oxo-2H-chromene-3-carbonitrile;3-Cyano-7-hydroxycoumarin *CAS 19088-73-4*;7-hydroxy-2-oxo-1-benzopyran-3-carbonitrile;3-Cyano-7-hydroxycoumarin ISO 9001：2015 REACH
CBNumber: CB1344231
Molecular Formula: C10H5NO3
Formula Weight: 187.15
MOL File: 19088-73-4.mol

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3-Cyano-7-hydroxycoumarin Property

Melting point:: ≥250 °C(lit.)
Boiling point:: 436.6±45.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMF: soluble
pka: 7.03 ± 0.20, most acidic, temperature: 25 °C
form: powder to crystal
color: Yellow solid or powder
λmax: 408 nm (Buffer pH 9); 408 nm (MeOH)
BRN: 153271
Major Application: Electroluminescentdevice;laser dyes; modified polyester for foodcontainers/beverage bottles; monitoring of cationicphotopolymerization processes;textiles;thin films
Biological Applications: Detectingmicroorganisms,nucleic acids; inhibiting cellproliferation/tumor growth; reference standard foresters; ethers,phosphates substrates; asa substrate for measuring nucleic acid polymerasesactivity; treating viral or parasite infections
InChIKey: IJQYTHQDUDCJEQ-UHFFFAOYSA-N
CAS DataBase Reference: 19088-73-4

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 8
HS Code: 2932.20.4500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 28605
Product name: 3-Cyanoumbelliferone
Purity: BioReagent, suitable for fluorescence, ≥98.0% (TLC)
Packaging: 100mg
Price: $162
Updated: 2025/07/31

Sigma-Aldrich

Product number: 28605
Product name: 3-Cyanoumbelliferone
Purity: BioReagent, suitable for fluorescence, ≥98.0% (TLC)
Packaging: 500mg
Price: $619
Updated: 2025/07/31

TCI Chemical

Product number: C2834
Product name: 3-Cyanoumbelliferone
Purity: >98.0%(GC)
Packaging: 1g
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: C2834
Product name: 3-Cyanoumbelliferone
Purity: >98.0%(GC)
Packaging: 5g
Price: $259
Updated: 2025/07/31

TRC

Product number: C991925
Product name: 3-Cyanoumbelliferone
Packaging: 500mg
Price: $310
Updated: 2021/12/16

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3-Cyano-7-hydroxycoumarin Chemical Properties,Usage,Production

Uses

3-Cyanoumbelliferone is a calibration standard.

Uses

3-Cyano-7-hydroxycoumarin has been the most widely used fluorophores for preparing fluorogenic substrates.As a blue-fluorescent probe used as a reference standard.

Synthesis

105-56-6

95-01-2

19088-73-4

GENERAL METHOD: α-substituted ethyl acetate (1.0 mmol) and phenyl iododo diacetate (1.0 mmol) were dissolved in ethanol (5 mL) under continuous stirring conditions. After 10 min of reaction, benzaldehyde or salicylaldehyde (1.0 mmol) was added to the system and the reaction was continued with stirring until the appropriate time. The progress of the reaction was monitored by thin layer chromatography (TLC). After the TLC showed that the reaction was complete, the ethanol was evaporated under reduced pressure. Subsequently, the product was extracted with ethyl acetate and the organic phase was dried with anhydrous sodium sulfate (Na2SO4) and concentrated again under reduced pressure to remove the solvent. The resulting crude product was purified by recrystallization from a solvent mixture of ethyl acetate and hexane to finally obtain the target compound 7-hydroxy-2-oxochromene-3-carbonitrile (3a-3h and 4a-4r series derivatives).

References

[1] Synthetic Communications, 2005, vol. 35, # 6, p. 785 - 790
[2] Phosphorus, Sulfur and Silicon and the Related Elements, 2002, vol. 177, # 11, p. 2555 - 2559
[3] Tetrahedron Letters, 2017, vol. 58, # 32, p. 3183 - 3187
[4] Journal of Heterocyclic Chemistry, 2007, vol. 44, # 4, p. 867 - 870
[5] Journal of the Iranian Chemical Society, 2016, vol. 13, # 1, p. 149 - 153

3-Cyano-7-hydroxycoumarin Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Cyano-7-hydroxycoumarin Suppliers

Americas 1 Canada 1 China 89 Europe 1 Germany 2 India 9 Japan 1 Switzerland 3 United Kingdom 3 United States 14 Global 124

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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Capot Chemical Co., Ltd

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Tianjin heowns Biochemical Technology Co., Ltd.

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Tianjin Derchemist Science & Technology Co., Ltd.

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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TCI Europe

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TCI AMERICA

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View Lastest Price from 3-Cyano-7-hydroxycoumarin manufacturers

R&D Scientific Inc.

Product: 3-Cyano-7-hydroxycoumarin 19088-73-4
Price: US $2450.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-09-06

Dideu Industries Group Limited

Product: 3-Cyano-7-hydroxycoumarin 19088-73-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-01

Career Henan Chemical Co

Product: 3-Cyano-7-hydroxycoumarin 19088-73-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-09

19088-73-4, 3-Cyano-7-hydroxycoumarinRelated Search:

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3-CYANOUMBELLIFERONE

3-CYANO-7-HYDROXYCOUMARIN

3-CYANOUMBELLIFERONE, FOR FLUORESCENCE*

7-hydroxy-2-oxo-2H-chromene-3-carbonitrile

7-Hydroxy-2-oxochromene-3-carbonitrile

3-CyanouMbelliferone [3-Cyano-7-hydroxycouMarin]

3-Cyano-7-hydroxycoumarin *CAS 19088-73-4*

7-hydroxy-2-oxo-1-benzopyran-3-carbonitrile

3-Cyano-7-hydroxycoumarin 95+%

3-Cyanoumbelliferone&gt

2H-1-Benzopyran-3-carbonitrile, 7-hydroxy-2-oxo-

3-Cyano-7-hydroxycoumarin ISO 9001：2015 REACH

3-Cyanoumbelliferone (3-cyano-7-hydroxycoumarin), Fluorometric agent

19088-73-4

C10H5NO3

Alphabetical

Fluorescent Indicators and Probes

Fluorescent Probes, Labels, Particles and Stains

pH Sensitive Probes and Indicators

Biochemicals and Reagents

BioChemical

heterocyclic/Aliphatic series

AMCA