ChemicalBook > CAS DataBase List > 3-CYANO-7-ETHOXYCOUMARIN

3-CYANO-7-ETHOXYCOUMARIN

Product Name
3-CYANO-7-ETHOXYCOUMARIN
CAS No.
117620-77-6
Chemical Name
3-CYANO-7-ETHOXYCOUMARIN
Synonyms
3-CETC;3-CYANO-7-ETHOXYCOUMARIN;CEC [3-Cyano-7-ethoxycoumarin;7-ETHOXYCOUMARIN-3-CARBONITRILE;7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile;3-CYANO-7-ETHOXYCOUMARIN ISO 9001：2015 REACH;7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile;2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-;CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6*;2H-1-Benzopyran-3-carbonitrile,7-ethoxy-2-oxo-(9CI)
CBNumber
CB2732282
Molecular Formula
C12H9NO3
Formula Weight
215.2
MOL File
117620-77-6.mol
More
Less

3-CYANO-7-ETHOXYCOUMARIN Property

Melting point:
210-212°C
Boiling point:
396.8±42.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble
form 
Solid
color 
yellow to orange
λmax
356 nm (Buffer pH7); 355 nm(MeOH)
Biological Applications
As a substrate for measuring cytochrome P450 enzymes activity; cytochrome P450 inhibition assays; drug design; drug metabolism; treating viral or parasite infections.
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
UC455
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥97% (HPLC)
Packaging
5mg
Price
$279
Updated
2023/06/20
Sigma-Aldrich
Product number
UC455
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥97% (HPLC)
Packaging
10mg
Price
$509
Updated
2023/06/20
Cayman Chemical
Product number
25441
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥95%
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
25441
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥95%
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
25441
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥95%
Packaging
25mg
Price
$193
Updated
2024/03/01
More
Less

3-CYANO-7-ETHOXYCOUMARIN Chemical Properties,Usage,Production

Uses

Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.

Uses

3-Cyano-7-ethoxycoumarin has been used as a substrate in cytochrome P (CYP) inhibition for fluorescence measurement.

General Description

3-Cyano-7-ethoxycoumarin is a fluorescent substrate for Cytochrome P450 1A1 (CYP1A1), Cytochrome P450 1A2 (CYP1A2), Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19).

Biochem/physiol Actions

Fluorescent probe useful in microsomal dealkylase studies. Typical drug-drug interactions resulting from enzyme inhibition.

3-CYANO-7-ETHOXYCOUMARIN Preparation Products And Raw materials

Raw materials

Malononitrile 4-Ethoxyphenol Chloroform Hydrochloric acid Sodium bicarbonate Methanol Sodium hydroxide

Preparation Products

More
Less

3-CYANO-7-ETHOXYCOUMARIN Suppliers

China 108 Europe 1 Germany 2 India 3 Switzerland 2 United Kingdom 4 United States 23 Global 143
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
EnliPharma Technology Co., Ltd
Tel
0551-66399836 18955197623
Email
sales@enlipharma.com
Country
China
ProdList
1874
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
1009
Advantage
55
Guangzhou Zhiya Chemdrugs Co.,Ltd
Tel
18122150900
Fax
QQ:2869377561
Email
sculk28@163.com
Country
China
ProdList
646
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
021-51619050 13301662590
Fax
+86-21-51619052
Email
mandy@atkchemical.com
Country
China
ProdList
8026
Advantage
55
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Grice Rand (Tianjin) Pharmaceutical Co., Ltd.
Tel
022-83705301 13752403750
Fax
022-83705301
Email
2966024760@qq.com
Country
China
ProdList
996
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7266
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Medi-tech Bioscientific Co., Ltd.
Tel
0519-83246372 13585352506
Fax
0519-83246372
Country
China
ProdList
1844
Advantage
58
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Heze Development Zone chuangli Chemical Co., Ltd.
Tel
+86-530-529 6766，+86-15666160102 15666160102
Fax
0530-529 6766
Email
info@chuangli-chem.com
Country
China
ProdList
894
Advantage
55
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
Advantage
58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3251
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12373
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22883
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
Amel Pharmatech Corporation
Tel
888-4366503
Fax
888-502-1736
Email
sales@amelpharmatech.com
Country
China
ProdList
4266
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58
Nanjing xiangrui technology co. LTD
Tel
021-021-00000000 15715199582
Email
njrich168@163.com
Country
China
ProdList
684
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ：63313187
Email
63313187@qq.com
Country
China
ProdList
1988
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988968278
Fax
QQ：3283937693
Email
sales@ubiochem.com
Country
China
ProdList
4297
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
Zhende Chemical Technology (Shanghai) Co., Ltd.
Tel
15601952568
Fax
3004479441
Email
sales4@myuchem.com
Country
China
ProdList
3105
Advantage
58
Shanghai Botuo Biotechnology Co., LTD
Tel
16621358918
Fax
QQ:402135374
Email
botuopharma888@163.com
Country
China
ProdList
9208
Advantage
58
Wuhan Chemstan Biotechnology Co., Ltd.
Tel
027-65317797 15926423062
Fax
QQ：422450190
Email
422450190@qq.com
Country
China
ProdList
10361
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15342225168
Email
yutianchun2007@126.com
Country
China
ProdList
10002
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Krain Pharmaceutical Technology CO.,Ltd
Tel
18252089365
Email
Krain_kerun@163.com
Country
China
ProdList
2618
Advantage
58
cjbscvictory
Tel
13348960310 13348960310
Email
3003867561@qq.com
Country
China
ProdList
10002
Advantage
58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
ProdList
4494
Advantage
58
Shanghai kadel chemical technology co., LTD
Tel
021-4007787-550 400-7787-550
Email
2850202386@qq.com
Country
China
ProdList
10594
Advantage
58
More
Less

View Lastest Price from 3-CYANO-7-ETHOXYCOUMARIN manufacturers

Dideu Industries Group Limited
Product
3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-01
Career Henan Chemical Co
Product
3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-09
Career Henan Chemical Co
Product
3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99
Supply Ability
1ton
Release date
2019-07-09

117620-77-6, 3-CYANO-7-ETHOXYCOUMARINRelated Search:

CoumarinDerivatives Coumarin-3-carboxylic acid Sodium cyanoborohydride 7-Ethoxycoumarin 3-(3-methoxyphenoxy)propanenitrile 7-METHOXY-2H-CHROMENE-3-CARBONITRILE 3-Cyano-7-hydroxycoumarin 4-METHOXYCINNAMONITRILE 3-CYANOCOUMARIN 2H-CHROMENE-3-CARBONITRILE 3-CYANO-7-ETHOXYCOUMARIN

  • 7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile
  • 7-ETHOXYCOUMARIN-3-CARBONITRILE
  • 3-CYANO-7-ETHOXYCOUMARIN
  • 2H-1-Benzopyran-3-carbonitrile,7-ethoxy-2-oxo-(9CI)
  • 7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
  • 3-Cyano-7-ethoxycoumarin [7-Ethoxycoumarin-3-carbonitrile] *Cytochrome P450 Substrate*
  • CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6*
  • CEC [3-Cyano-7-ethoxycoumarin
  • 2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-
  • 3-CYANO-7-ETHOXYCOUMARIN ISO 9001：2015 REACH
  • 3-CETC
  • 117620-77-6
  • 11620-77-6
  • BioChemical
  • Biochemicals and Reagents
  • Luminescent Compounds/Detection
  • Other luminescent compounds
  • ETHOXY
  • Coumarins
  • Detection and Quantitation
  • Reagents
  • Multi-Drug Resistance and Drug Metabolism
  • Drug and Xenobiotic Metabolism
  • Substrates, Inducers, Inhibitors