ChemicalBook > CAS DataBase List > 3-CYANO-7-ETHOXYCOUMARIN

3-CYANO-7-ETHOXYCOUMARIN

Product Name
3-CYANO-7-ETHOXYCOUMARIN
CAS No.
117620-77-6
Chemical Name
3-CYANO-7-ETHOXYCOUMARIN
Synonyms
3-CETC;3-CYANO-7-ETHOXYCOUMARIN;CEC [3-Cyano-7-ethoxycoumarin;7-ETHOXYCOUMARIN-3-CARBONITRILE;7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile;3-CYANO-7-ETHOXYCOUMARIN ISO 9001：2015 REACH;7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile;2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-;CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6*;2H-1-Benzopyran-3-carbonitrile,7-ethoxy-2-oxo-(9CI)
CBNumber
CB2732282
Molecular Formula
C12H9NO3
Formula Weight
215.2
MOL File
117620-77-6.mol
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3-CYANO-7-ETHOXYCOUMARIN Property

Melting point:
210-212°C
Boiling point:
396.8±42.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble
form 
Solid
color 
yellow to orange
λmax
356 nm (Buffer pH7); 355 nm(MeOH)
Biological Applications
As a substrate for measuring cytochrome P450 enzymes activity; cytochrome P450 inhibition assays; drug design; drug metabolism; treating viral or parasite infections.
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
UC455
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥97% (HPLC)
Packaging
5mg
Price
$279
Updated
2023/06/20
Sigma-Aldrich
Product number
UC455
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥97% (HPLC)
Packaging
10mg
Price
$509
Updated
2023/06/20
Cayman Chemical
Product number
25441
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥95%
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
25441
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥95%
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
25441
Product name
3-Cyano-7-ethoxycoumarin
Purity
≥95%
Packaging
25mg
Price
$193
Updated
2024/03/01
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3-CYANO-7-ETHOXYCOUMARIN Chemical Properties,Usage,Production

Uses

Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.

Uses

3-Cyano-7-ethoxycoumarin has been used as a substrate in cytochrome P (CYP) inhibition for fluorescence measurement.

General Description

3-Cyano-7-ethoxycoumarin is a fluorescent substrate for Cytochrome P450 1A1 (CYP1A1), Cytochrome P450 1A2 (CYP1A2), Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19).

Biochem/physiol Actions

Fluorescent probe useful in microsomal dealkylase studies. Typical drug-drug interactions resulting from enzyme inhibition.

3-CYANO-7-ETHOXYCOUMARIN Preparation Products And Raw materials

Raw materials

Malononitrile 4-Ethoxyphenol Chloroform Hydrochloric acid Sodium bicarbonate Methanol Sodium hydroxide

Preparation Products

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3-CYANO-7-ETHOXYCOUMARIN Suppliers

China 110 Europe 1 Germany 2 India 4 Switzerland 2 United Kingdom 4 United States 22 Global 145
Absin Bioscience Inc.
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View Lastest Price from 3-CYANO-7-ETHOXYCOUMARIN manufacturers

Dideu Industries Group Limited
Product
3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-01
Career Henan Chemical Co
Product
3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-09
Career Henan Chemical Co
Product
3-CYANO-7-ETHOXYCOUMARIN 117620-77-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99
Supply Ability
1ton
Release date
2019-07-09

117620-77-6, 3-CYANO-7-ETHOXYCOUMARINRelated Search:

CoumarinDerivatives Coumarin-3-carboxylic acid Sodium cyanoborohydride 7-Ethoxycoumarin 3-(3-methoxyphenoxy)propanenitrile 7-METHOXY-2H-CHROMENE-3-CARBONITRILE 3-Cyano-7-hydroxycoumarin 4-METHOXYCINNAMONITRILE 3-CYANOCOUMARIN 2H-CHROMENE-3-CARBONITRILE 3-CYANO-7-ETHOXYCOUMARIN

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  • 3-Cyano-7-ethoxycoumarin [7-Ethoxycoumarin-3-carbonitrile] *Cytochrome P450 Substrate*
  • CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6*
  • CEC [3-Cyano-7-ethoxycoumarin
  • 2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-
  • 3-CYANO-7-ETHOXYCOUMARIN ISO 9001：2015 REACH
  • 3-CETC
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  • 11620-77-6
  • BioChemical
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