Brompheniramine hydrogen maleate

ChemicalBook > CAS DataBase List > Brompheniramine hydrogen maleate

Brompheniramine hydrogen maleate

Product Name: Brompheniramine hydrogen maleate
CAS No.: 980-71-2
Chemical Name: Brompheniramine hydrogen maleate
Synonyms: dimegan;dimetane;dimotane;ilvinmaleate;Rolabromophen;dimetanemaleate;Brompheniramine MaL;BroMpheniraMine hydr;parabromdylaminemaleate;BROMPHENIRAMINE MALEATE
CBNumber: CB2736194
Molecular Formula: C20H23BrN2O4
Formula Weight: 435.31
MOL File: 980-71-2.mol

Less

Brompheniramine hydrogen maleate Property

Melting point:: 134-135°C
Flash point:: 9℃
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in water, freely soluble in ethanol (96 per cent), in methanol and in methylene chloride.
color: White to Off-White
λmax: 261nm(lit.)
Merck: 14,1443
Stability:: Hygroscopic
InChIKey: SRGKFVAASLQVBO-BTJKTKAUSA-N
LogP: 3.565 (est)
CAS DataBase Reference: 980-71-2(CAS DataBase Reference)
EPA Substance Registry System: 2-Pyridinepropanamine, .gamma.-(4-bromophenyl)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1) (980-71-2)

Less

Safety

Hazard Codes: Xn,Xi,T,F
Risk Statements: 22-39/23/24/25-23/24/25-11
Safety Statements: 36-45-36/37-16-7
RIDADR: 3249
WGK Germany: 3
RTECS: US4025000
TSCA: Yes
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 38220090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B-043
Product name: Brompheniramine maleate solution
Purity: 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $50
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1078008
Product name: (±)-Brompheniramine maleate salt
Packaging: 125mg
Price: $358
Updated: 2024/03/01

TCI Chemical

Product number: B5167
Product name: Brompheniramine Maleate
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $91
Updated: 2024/03/01

Alfa Aesar

Product number: J63922
Product name: Brompheniramine maleate
Packaging: 25mg
Price: $85.65
Updated: 2024/03/01

Alfa Aesar

Product number: J63922
Product name: Brompheniramine maleate
Packaging: 100mg
Price: $249
Updated: 2021/12/16

Less

Brompheniramine hydrogen maleate Chemical Properties,Usage,Production

Description

Brompheniramine is a first generation antihistamine of the propylamine class. It antagonizes histamine H₁ receptors (K_i = 6.06 nM) and also inhibits the reuptake of serotonin and norepinephrine.

Chemical Properties

White Solid

Originator

Dimetane,Robins,US,1957

Uses

This drug is only available in combination with other medications: Bromfed, Dimetane, Dimetapp, Drixomed, Histatab, Nasahist. The only difference between this agent and chlorpheniramine is the substitution of a bromine for a chlorine atom in brompheniramine.

Uses

Antihistaminic;H1 Antagonist

Uses

An antihistamine and also an inhibitor of serotonin reuptake

Definition

ChEBI: The maleic acid salt of brompheniramine. A histamine H1 receptor antagonist, it is used for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.

Manufacturing Process

Initially, 4-bromobenzyl-cyanide is reacted with sodium amide and 2- chloropyridine to give bromophenyl-pyridyl acetonitrile. This is then reacted with sodium amide then dimethyl amino ethyl chloride to give 4-bromophenyldimethylaminoethyl- pyridyl acetonitrile. This intermediate is then hydrolyzed and decarboxylated to bromphenirame using 80% H2SO4 at 140°-150°C for 24 hours. The brompheniramine maleate may be made by reaction with maleic acid in ethanol followed by recrystallization from pentanol.

brand name

Dimetane (Wyeth).

Therapeutic Function

Antihistaminic

General Description

Brompheniraminemaleate, (+)2-[p-bromo-α-[2-(dimethylamino)ethyl]benzyl]pyridine bimaleate (Dimetane), differs fromchlorpheniramine by the substitution of a bromine atom forthe chlorine atom. Its actions and uses are like those of chlorpheniramine.It has a half-life of 25 hours, which is almosttwice that of chlorpheniramine.

Side effects

The side effects of this medication are similar to other classes of sedative antihistamines. Some medications include parabens. Patients sensitive to parabens may develop a sensitivity reaction.

Brompheniramine hydrogen maleate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Brompheniramine hydrogen maleate Suppliers

Americas 1 Austria 1 Belgium 1 Canada 2 China 127 Europe 2 France 1 Germany 7 India 56 Japan 1 Malaysia 1 Philippines 1 Poland 1 Slovakia 1 South Korea 1 Spain 1 Switzerland 2 Turkey 1 United Arab Emirates 1 United Kingdom 12 United States 44 Venezuela 1 Global 266

Shenyang Syndy Chemistry Institute

Tel: 86 24 25521318
Fax: +86 24 25510806
Country: China
ProdList: 16
Advantage: 42

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9664
Advantage: 60

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4505
Advantage: 50

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1958
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13358
Advantage: 58

Shanghai CanSpecsci Instrument Co., Ltd.

Tel: 400-6087598 15021221957
Fax: 4006087598-8012
Email: order@canspecsci.com
Country: China
ProdList: 2071
Advantage: 56

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9972
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4515
Advantage: 55

Zhengzhou Alfachem Co.,Ltd.

Tel: 0371-53778726 18003825608
Fax: QQ：2885354392
Email: liuxiaoyan@alfachem.cn
Country: China
ProdList: 1946
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

Raw material medicin reagent co.,Ltd

Tel: 025-57798860
Email: sales@njromanme.com
Country: China
ProdList: 4534
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Wuhan Magic Biological Technology Co., Ltd.

Tel: 18872289958、027-52304252、3400508168
Fax: 027-52304252
Email: 3400508168@qq.com
Country: China
ProdList: 1910
Advantage: 55

Guangzhou Kafen Biotech Co.,Ltd

Tel: 18029243487 2355327168
Fax: 020-31121510
Email: gy@yccreate.com
Country: China
ProdList: 4753
Advantage: 55

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9506
Advantage: 60

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28822
Advantage: 58

Zhuhai JiaYi Biological Technology Co., Ltd.

Tel: 18578209868 2355327026
Fax: 18578209868 QQ：2355327026
Email: steroidbest@hotmail.com
Country: China
ProdList: 6504
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15085
Advantage: 58

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15495
Advantage: 58

Conier Chem & Pharma Limited

Tel: 13368167990
Email: sales@conier.com
Country: China
ProdList: 2809
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17997
Advantage: 58

Foshan DaoQi Biological Co., Ltd.

Tel: 18062666947
Fax: 18062666959
Email: 2355880548@qq.com
Country: China
ProdList: 4229
Advantage: 58

Hubei Hengluyuan Technology Co., Ltd.

Tel: 027-88188016 18986219475
Fax: +86-02788188026
Email: 1764683941@qq.com
Country: China
ProdList: 576
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10305
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20569
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4392
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

Guangzhou Tomums Life Science Co., Ltd.

Tel: 020-31155029 18902330969
Fax: 020-31155029
Email: sales@tomums.cn
Country: China
ProdList: 4698
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: 0551-65418671
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34572
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: CHINA
ProdList: 52867
Advantage: 58

Less

View Lastest Price from Brompheniramine hydrogen maleate manufacturers

Hebei Duling International Trade Co. LTD

Product: Brompheniramine hydrogen maleate 980-71-2
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 30 tons
Release date: 2023-04-17

Shaanxi Dideu Medichem Co. Ltd

Product: Brompheniramine hydrogen maleate 980-71-2
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-05-08

Wuhan Han Sheng New Material Technology Co.，Ltd

Product: Brompheniramine Maleate 980-71-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.76%
Supply Ability: 20tons
Release date: 2023-04-19

980-71-2, Brompheniramine hydrogen maleateRelated Search:

Chlorodimethylphenylsilane Chlorphenamine maleate Diethylstilbestrol Hydrogen Enalapril maleate DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Maleic acid Polybutene 2,6-Lutidine Trimebutine maleate Cinepazide maleate CIS-BUTENEDIOIC ANHYDRIDE Rosiglitazone maleate Disodium fumarate Propane HYDROGEN CYANIDE (-)-2-[METHYLAMINO]-1-PHENYLPROPANE D/L-AMPHETAMINE HYDROCHLORIDE

2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate(1:1)

2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)-pyridinmaleate(1:1)

dimegan

dimetane

dimetanemaleate

RS-brompheniramine maleate

dimotane

g-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanaminemaleate

gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(z)-2-butenedioate

gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(z)-butenedioate

ilvinmaleate

parabromdylaminemaleate

parabromodylaminemaleate

γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanaminemaleate

1-(n,n-dimethylamino)-3-(p-bromophenyl)-3-(alpha-pyridyl)propane maleate

1-p-bromophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate

BROMOPHENIRAMINE MALEATE

(+/-)-BROMPHENIRAMINE MALEATE SALT

BROMPHENIRAMINE MALEATE SALT

brompheniramine hydrogen maleate

BROMPHENIRAMINE MALEATE

BROMPHENIRAMINEMALEATE,USP

BROMPHENIRAMINE MALEATE, PHARMA

Bromopheniramine Maleate Salt

Brompheniramine Maleate (125 mg)

BroMpheniraMine hydr

γ-(4-BroMophenyl)-N,N-diMethyl-

γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanamine,(2Z)-2-butenedioate (1:1)

Brompheniramine maleate solution

Brompheniramine maleate CRS

Rolabromophen

Brompheniramine MaL

3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate

Brompheniramine hydrogen maleate USP/EP/BP

Brompheniramine maleateQ: What is Brompheniramine maleate Q: What is the CAS Number of Brompheniramine maleate Q: What is the storage condition of Brompheniramine maleate Q: What are the applications of Brompheniramine maleate

TIANFU-CHEM 980-71-2 Brompheniramine hydrogen maleate

Brompheniramine Maleate (1078008)

β-Phenyl-γ-aminobutyric acid

980-71-2

80-71-2

C4H4O4C16H19BrN2

C20H23BrN204

C20H23BrN2O4

C16H19BrN2C4H4O4C20H23BrN2O4

C16H19BrN2C4H4O4

C16H19BrN2C4H4O4C20H

C16H19BrN2C4H4

Amines

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals