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2,3-DIAMINOTOLUENE

Product Name
2,3-DIAMINOTOLUENE
CAS No.
2687-25-4
Chemical Name
2,3-DIAMINOTOLUENE
Synonyms
Toluene-2,3-diamine;2,3-DAT;25KGS/DRUM;2.3-DiaMinotol;2,3-Dhamphetamine;2,3-Diaminotoluone;2,3-Diaminetoluene;2,3-TOLUENEDIAMINE;2,3-DIAMINOTOLUENE;2,3-Tolylenediamine
CBNumber
CB2736932
Molecular Formula
C7H10N2
Formula Weight
122.17
MOL File
2687-25-4.mol
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2,3-DIAMINOTOLUENE Property

Melting point:
59-65 °C (lit.)
Boiling point:
225°C
Density 
1.0343 (rough estimate)
refractive index 
1.5103 (estimate)
Flash point:
225°C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Dichloromethane
pka
4.28±0.10(Predicted)
form 
Powder or Crystals
color 
Brown to dark brown
BRN 
907184
InChI
InChI=1S/C7H10N2/c1-5-3-2-4-6(8)7(5)9/h2-4H,8-9H2,1H3
InChIKey
AXNUJYHFQHQZBE-UHFFFAOYSA-N
SMILES
C1(N)=CC=CC(C)=C1N
CAS DataBase Reference
2687-25-4(CAS DataBase Reference)
EPA Substance Registry System
1,2-Benzenediamine, 3-methyl- (2687-25-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36-36/37/39
RIDADR 
2811
WGK Germany 
3
RTECS 
XS9550000
Hazard Note 
Harmful/Irritant
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29214990
Hazardous Substances Data
2687-25-4(Hazardous Substances Data)
Toxicity
mouse,LD50,intraperitoneal,286mg/kg (286mg/kg),Genetica Polonica. Vol. 26, Pg. 109, 1985.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
272361
Product name
2,3-Diaminotoluene
Purity
97%
Packaging
5g
Price
$99.8
Updated
2025/07/31
TCI Chemical
Product number
D3788
Product name
2,3-Diaminotoluene
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$177
Updated
2025/07/31
TCI Chemical
Product number
D3788
Product name
2,3-Diaminotoluene
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$654
Updated
2025/07/31
TRC
Product number
D416825
Product name
2,3-Diaminotoluene
Packaging
5g
Price
$75
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK419555
Product name
2,3-Diaminotoluene
Purity
97%
Packaging
5g
Price
$88
Updated
2021/12/16
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2,3-DIAMINOTOLUENE Chemical Properties,Usage,Production

Chemical Properties

brown powder

Uses

Inducer of CYP1A activity, and possible mutagenic carcinogen.

General Description

The antitumour activity of Pd(II) and Pt(II) new complexes with 2,3-diaminotoluene was studied. 2,3-Diaminotoluene induced CYP1A activity.

Synthesis

570-24-1

2687-25-4

General procedure for the synthesis of 2,3-diaminotoluene from 2-methyl-6-nitroaniline: 4.0 g of 10% palladium-carbon catalyst (51.5% in water) was added to 200 ml of ethanol solution containing 8.50 g (55.9 mmol) of 2-methyl-6-nitroaniline. The reaction mixture was stirred at room temperature and atmospheric pressure in a hydrogen atmosphere for 4 hours. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was subsequently removed by evaporation from the filtrate to afford 6.64 g (97% yield) of 2,3-diaminotoluene crude product in the form of black crystals. The product could be used directly in the subsequent reaction without further purification.1H-NMR (CDCl3) δ: 2.22 (3H, s), 3.35-3.40 (4H, m), 6.62-6.68 (3H, m).

References

[1] Patent: EP1479681, 2004, A1. Location in patent: Page 110
[2] Polyhedron, 2016, vol. 105, p. 137 - 149
[3] Patent: US2012/130078, 2012, A1. Location in patent: Page/Page column 6
[4] Heterocycles, 1997, vol. 45, # 5, p. 955 - 962
[5] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 5, p. 543 - 548

2,3-DIAMINOTOLUENE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DIAMINOTOLUENE Suppliers

Americas 1 Belgium 3 Canada 2 China 215 Europe 1 France 2 Germany 6 Hungary 1 India 22 Japan 3 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 3 United Kingdom 18 United States 40 Global 323
Acros Organics (Part of Thermo Fisher Scientific )
Tel
--
Fax
--
Email
fo@acros.com
Country
Belgium
ProdList
3824
Advantage
58
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
Maybridge Chemical Co., Ltd.
Tel
--
Fax
--
Country
Belgium
ProdList
6293
Advantage
73
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View Lastest Price from 2,3-DIAMINOTOLUENE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2,3-DIAMINOTOLUENE 2687-25-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-26
Shijiazhuang tongyang Import and Export Co., LTD
Product
2,3-DIAMINOTOLUENE 2687-25-4
Price
US $22.00/KG
Min. Order
1g
Purity
99.9%
Supply Ability
500000kgs
Release date
2021-08-13
Career Henan Chemical Co
Product
2,3-DIAMINOTOLUENE 2687-25-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

2687-25-4, 2,3-DIAMINOTOLUENERelated Search:

2,5-DIAMINOTOLUENE Diaminomaleonitrile BIS-2,6-N,N-(2-HYDROXYETHYL)DIAMINOTOLUENE 2,5-Diaminotoluene 2HCL,3,4-DIAMINOTOLUENE DIHYDROCHLORIDE,2,5-DIAMINOTOLUENE DIHYDROCHLORIDE,2,5-DIAMINOTOLUENE DI HCL 2-Methyl-6-nitroaniline Vat Blue 4 Vat Blue 6 3,4-DIMETHYL-O-PHENYLENEDIAMINE 2-NITRO-3-AMINOBENZOIC ACID 2,3-DINITROTOLUENE 1,2-DIAMINOANTHRAQUINONE 2,3-DIMETHYL-6-NITROANILINE 4,6-DIMETHYL-2-NITROANILINE 3,5-Dimethylthio-2,6-diaminotoluene 2,5-DIAMINOTOLUENE SULFATE,2,5-DIAMINOTOLUENE SULPHATE 2,6-diaminotoluene-4-sulphonic acid 2,4-DIAMINOTOLUENE OEKANAL, 250 MG,2,4-DIAMINOTOLUENE, 1000MG, NEAT,2,4-Diaminotoluene,98%,META-DIAMINOTOLUENE,2,4-toluenediamine(2,4-diaminotoluene 3,4-Diaminotoluene,97%,3,4-Diaminotoluene, sublimed, 99%,3,4-DIAMINOTOLUENE

  • 2,3-Diaminotoluene(3-Methyl-o-phenylenediamine)
  • 2.3-DiaMinotol
  • 2,3-Diaminetoluene
  • 2,3-Diaminotoluone
  • 3-Methylbenzene-1,2-diamine98%
  • 2-Benzenediamine,3-methyl-1
  • 3-Methyl-1,2-benzenediamine
  • 3-methyl-1,2-phenylenediamine[qr]
  • 3-methyl-2-benzenediamine
  • 3-methyl-o-phenylenediamine[qr]
  • toluene,2,3-diamino-[qr]
  • Toluene-2,3-diamine
  • toluene-2,3-diamine[qr]
  • 2,3-DiaMinotoluene, 97% 1GR
  • 2,3-DiaMinotoluene, 97% 5GR
  • 1-Methyl-2,3-phenylenediaMine
  • 2-AMino-3-Methylaniline
  • 3-Methyl-1,2-diaMinobenzene
  • 3-Methyl-1,2-phenylenediamine Tolylene-2,3-diamine
  • 2-Amino-3-methylphenylamine
  • 2,3-Diaminotoluene, 1,2-Diamino-3-methylbenzene
  • 3-Methylbenzene-1,2-diamine 98%
  • 3-METHYL-BENZENE-1,2-DIAMINE
  • 2,3-Diaminotoluene 98%
  • ORTHO-DIAMINOTOLUENE
  • 2,3-DIAMINOTOLUENE OEKANAL, 250 MG
  • 1,2-diamino-3-methylbenzene
  • 2,3-Toluilenediamine
  • 2,3-Diaminotoluene,97%
  • VIC-O-TOLYLENEDIAMINE
  • 1,2-benzenediamine,3-methyl-
  • 1,2-benzenediamine,3-methyl-[qr]
  • 1,2-diamino-3-methylbenzene[qr]
  • 1-methyl-2,3-phenylenediamine[qr]
  • 2,3-Toluylenediamine
  • 2,3-toluylenediamine[qr]
  • 2,3-Tolylenediamine
  • 2,3-tolylenediamine[qr]
  • 3-METHYL-1,2-PHENYLENEDIAMINE
  • 3-METHYL-O-PHENYLENEDIAMINE
  • 2,3-TOLUENEDIAMINE
  • 2,3-DIAMINOTOLUENE
  • 2,3-Diamino Toluene,(2,3-DAT)
  • 25KGS/DRUM
  • 2,3-DAT
  • 2,3-Diaminotoluene&gt
  • Tolylene-2,3-diamine
  • 2,3-DIAMINOTOLUENE ISO 9001：2015 REACH
  • 2,3-Dhamphetamine
  • C12197500 2,3-Diaminotoluene
  • 2,3-Diaminotoluene, 95%
  • 2687-25-4
  • 10020-79-5
  • 5687-25-4
  • CH3C6H3NH22
  • AMINE
  • Nitrogen Compounds
  • Amines