ChemicalBook > CAS DataBase List > 4-Amino-6-bromoquinoline

4-Amino-6-bromoquinoline

Product Name
4-Amino-6-bromoquinoline
CAS No.
65340-73-0
Chemical Name
4-Amino-6-bromoquinoline
Synonyms
6-Bromoquinolin-4-amine;BUTTPARK 44\09-54;6-bromo-4-quinolinamine;4-AMINO-6-BROMOQUINOLINE;4-Quinolinamine, 6-bromo-;6-BROMO-QUINOLIN-4-YLAMINE;4-Amino-6-bromoquinoline ISO 9001：2015 REACH
CBNumber
CB2744087
Molecular Formula
C9H7BrN2
Formula Weight
223.07
MOL File
65340-73-0.mol
More
Less

4-Amino-6-bromoquinoline Property

Melting point:
228-230°C
Boiling point:
388.7±27.0 °C(Predicted)
Density 
1.649±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
solid
pka
8.21±0.50(Predicted)
Appearance
White to yellow Solid
More
Less

Safety

Hazard Codes 
T
Risk Statements 
25-36
Safety Statements 
26-45
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
2933499090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BBO000153
Product name
4-Amino-6-bromoquinoline
Purity
Aldrich
Packaging
1g
Price
$330
Updated
2025/07/31
TRC
Product number
A594840
Product name
4-Amino-6-bromoquinoline
Packaging
100mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA50975
Product name
4-Amino-6-bromoquinoline
Packaging
100mg
Price
$89
Updated
2021/12/16
AK Scientific
Product number
Z4998
Product name
4-Amino-6-bromoquinoline
Packaging
250mg
Price
$111
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA50975
Product name
4-Amino-6-bromoquinoline
Packaging
250mg
Price
$130
Updated
2021/12/16
More
Less

4-Amino-6-bromoquinoline Chemical Properties,Usage,Production

Synthesis

65340-70-7

65340-73-0

The general procedure for the synthesis of 4-amino-6-bromoquinoline from 6-bromo-4-chloroquinoline was as follows: 6-bromo-4-chloroquinoline (500 mg, 2.1 mmol), acetamide (2.438 g, 41.3 mmol), and potassium carbonate (1.449 g, 10.5 mmol) were added to a reaction flask fitted with a magnetic stirrer. The reaction mixture was heated to 180 °C and maintained at this temperature for 5 hours. After completion of the reaction, the mixture was cooled to room temperature and diluted with water (50 mL). The aqueous phase was extracted with ethyl acetate (20 mL × 3), the organic phases were combined and dried over anhydrous sodium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol = 20:1) to afford the target product 6-bromoquinolin-4-amine (198 mg, 43% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6) and LC-MS (ESI) to confirm its structure.1H NMR (400 MHz, DMSO-d6) δ 8.46 (d, J = 2.2 Hz, 1H), 8.25 (d, J = 7.2 Hz, 1H), 7.95 (dd, J = 8.9, 2.3 Hz, 1H), 7.69 (d, J = 8.9, 2.3 Hz, 1H), 7.69 (d, J = 8.9, 2.3 Hz, 1H), 7.95 (dd, J = 8.9, 2.3 Hz, 2.3 Hz, 1H) 7.69 (d, J = 8.9 Hz, 1H), 7.12 (d, J = 7.2 Hz, 1H), 5.64 (s, 2H). LC-MS (ESI) m/z = 223.1, 225.1 (M + H, M + 2 + H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 9, p. 1919 - 1922

4-Amino-6-bromoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Amino-6-bromoquinoline Suppliers

Canada 1 China 73 Germany 1 India 2 United Kingdom 6 United States 18 Global 101
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65

65340-73-0, 4-Amino-6-bromoquinolineRelated Search:

6-Hydroxy-2(1H)-3,4-dihydroquinolinone Isoquinoline 2-Bromoquinoline quinolinium hydrogen sulphate Quinhydrone 4-Aminoguinoline Bis(2-ethylhexyl)amine ALTRENOGEST 6-Bromoquinoline Quinclorac Glycine Ethoxyquin Triallylamine 8-Bromoquinoline 8-Hydroxyquinoline Tris(hydroxymethyl)aminomethane 4-AMINO-8-BROMOQUINOLINE 2-AMINO-4-BROMOQUINOLINE

  • 6-BROMO-QUINOLIN-4-YLAMINE
  • 4-AMINO-6-BROMOQUINOLINE
  • BUTTPARK 44\09-54
  • 6-Bromoquinolin-4-amine
  • 6-bromo-4-quinolinamine
  • 4-Quinolinamine, 6-bromo-
  • 4-Amino-6-bromoquinoline ISO 9001：2015 REACH
  • 65340-73-0